381 research outputs found

    The Intercultural Skills Graduates and Businesses in Europe Need Today

    Get PDF
    It was the aim of the two surveys with European graduates and employers respectively to investigate the importance of intercultural competencies and skills for student employability and business success for European enterprise, now and in the future. The two surveys gave important insights into key factors that support the development of intercultural skills and competencies for graduates and employers across four countries and five different European regions, as well as five distinct universities. Our analysis shows clearly that one of the most important factors is the key role of experience with, and exposure to, people from different cultural backgrounds. Both students and employers scored much higher on important intercultural competencies such as cultural empathy, cognitive flexibility, open-mindedness, and tolerance for ambiguity, if they had frequent interactions with people from other cultures. This was also true for speaking at least one or more foreign languages at an intermediate or advanced level. Foreign language competence is an important intercultural skill not only for communication but also an important way in which cultural empathy and cognitive flexibility are learned and trained. In line with these results, both students and employers who had more exposure to different cultures also felt there was more need to pay attention to intercultural issues and support the development of intercultural skills than those with less experience of different cultures. Furthermore, our results from both the student and the employer surveys seem to reflect differences between more urban/metropolitan centres and more rural areas with smaller towns. London and Bursa are the two largest cities and the most metropolitan areas in our sample with a more multicultural population, whereas Worcester and Leuven are both smaller cities and the regions with the least ethnic diversity. Halmstad falls somewhere in between with a similar size and ethnic composition of the city and region as Worcester and Leuven, but the university itself has a very multicultural and mature student body that is very similar to LSBU in central London. While we cannot directly influence these regional differences in urbanisation and multiculturalism it is certainly important to be aware of them

    Definition of two agonist types at the mammalian cold-activated channel TRPM8.

    Get PDF
    Various TRP channels act as polymodal sensors of thermal and chemical stimuli, but the mechanisms whereby chemical ligands impact on TRP channel gating are poorly understood. Here we show that AITC (allyl isothiocyanate; mustard oil) and menthol represent two distinct types of ligands at the mammalian cold sensor TRPM8. Kinetic analysis of channel gating revealed that AITC acts by destabilizing the closed channel, whereas menthol stabilizes the open channel, relative to the transition state. Based on these differences, we classify agonists as either type I (menthol-like) or type II (AITC-like), and provide a kinetic model that faithfully reproduces their differential effects. We further demonstrate that type I and type II agonists have a distinct impact on TRPM8 currents and TRPM8-mediated calcium signals in excitable cells. These findings provide a theoretical framework for understanding the differential actions of TRP channel ligands, with important ramifications for TRP channel structure-function analysis and pharmacology

    The Intercultural Skills Graduates and Businesses in Europe Need Today

    Get PDF
    This ERASMUS+ funded project, “Developing the cross-cultural skills of graduates in response to the needs of European enterprise”, is developed in response to recent research highlighting the importance of intercultural competencies for graduates wanting to work in Europe, the employers’ needs, and the intercultural competencies and skills higher education institutions provide. This project aims to develop the intercultural competencies of graduates in the EU by enhancing the quality and relevance of their knowledge and skills to enable them to be active professionals in the European working environment. Five Higher Education Institutions have participated in this study: University of Worcester (Project lead, UK), London South Bank University (UK), UC Leuven-Limburg (Belgium), Halmstad University (Sweden), and Bursa Uludağ University (Turkey). The diversity of these partners, their respective regional and national contexts, and their experience in working together with regional businesses are central to achieve the project aims. As the first output of the project, this report presents results based on two types of analysis methods and data collected from four European countries (UK, Sweden, Belgium, and Turkey). Firstly, two surveys and the quantitative analysis of data collected from 585 student surveys responses and 403 employer survey responses and secondly, on an analysis of qualitative data collected through 50 interviews with employees in European organizations and 50 interviews with students studying in European universities

    Pedobarographic analysis and quality of life after lisfranc fracture dislocation

    Get PDF
    Background: Few studies on tarsometatarsal fracture dislocations report on plantar pressure analysis and quality of life. The primary aim of this study was to determine the added value of plantar pressure analysis. The secondary aim was to determine quality of life and functional outcome. Materials and Methods: With a median followup of 76 months, 26 patients with an isolated Lisfranc injury participated. The Short Form 36 (SF-36) was used to determine the health related

    Ideal versus corrected body weight for dosage of sugammadex in morbidly obese patients

    Get PDF
    Summary To date, the dosing of sugammadex is based on real body weight without taking fat content into account. We compared the reversal of profound rocuronium-induced neuromuscular blockade in morbidly obese patients using doses of sugammadex based on four different weight corrections. One hundred morbidly obese patients, scheduled for laparoscopic bariatric surgery under propofolsufentanil anaesthesia, were randomly assigned four groups: ideal body weight; ideal body weight + 20%; ideal body weight + 40%; and real body weight. Patients received sugammadex 2 mg.k
    • …
    corecore