Seroepidemiology of group A rotavirus in suburban São Paulo, Brazil

Age-specifc patterns of rotavirus infection were investigated using a randomly selected and representative sample of sera from a suburban community of São Paulo, Brazil screened for class-specifc antibodies to group A rotavirus. Age-serology of anti-rotavirus IgG showed primary infection predominant in young infants with a median age of around 18 months consistent with IgM serology suggesting highest rates of recent infection between ages 4 and 48 months. Anti-rotavirus serum IgA prevalence increased gradually with age. Paired samples from infants, collected 1 month apart, indicated high exposure rates with seroconversion occurring in several infants during the reported low transmission season. Between 5 and 10% of adults had elevated IgM levels indicative of recent infection and, potentially, of an important contribution adults may play to rotavirus transmission. Further understanding of the dynamics of rotavirus transmission within populations, at group and serotype level, would benefit the design and monitoring of future immunization programmes

Budget 2002: business taxation measures

Following the 2002 Budget, this Briefing Note examines some of the Chancellor's changes to business taxation. A number of Budget measures, including the research and development tax credit for large companies and the exemption of capital gains on the sale of subsidiaries, are welcome and should improve the efficiency of the UK's tax system. All of these measures were subject to extensive prior consultation. A number of other measures were not foreshadowed in the Pre-Budget Report. Three of these are examined here - the new 0% rate of corporation tax, the changes to North Sea taxation and the new anti-avoidance measures for stamp duty

Using Defence Engagement (Health) to progress the Women Peace and Security agenda

Since the unanimous passing of United Nations Security Council Resolution 1325, which calls on member states to address gender inequality, many countries and the wider North Atlantic Treaty Organisation community have championed the Women Peace and Security agenda to empower women and reduce violence within fragile states. When women are empowered and actively involved in decision-making, there is less violence, and more peace and stability in that society, which benefits all members.Defence Medical Services are uniquely positioned to progress this agenda, particularly through its Defence Engagement activities. The UK’s military medical community has more women in leadership than the wider military community. Our personnel can and should be used to model and empower military healthcare workers in partner nations. This paper forms part of a special issue of BMJ Military Health dedicated to Defence Engagement

Standardization of the NEO-PI-3 in the Greek general population

BACKGROUND: The revised NEO Personality Inventory (NEO-PI-3) includes 240 items corresponding to the Big Five personality traits (Extraversion, Agreeableness, Conscientiousness, Neuroticism, and Openness to Experience) and subordinate dimensions (facets). It is suitable for use with adolescents and adults (12 years or older). The aim of the current study was to validate the Greek translation of the NEO-PI-3 in the general Greek population. MATERIAL AND METHODS: The study sample included 734 subjects from the general Greek population of whom 59.4% were females and 40.6% males aged 40.80 +/- 11.48. The NEO-PI-3 was translated into Greek and back-translated into English, and the accuracy of the translation was confirmed and established. The statistical analysis included descriptive statistics, confirmatory factorial analysis (CFA), the calculation of Cronbach's alpha, and the calculation of Pearson product-moment correlations. Sociodemographics groups were compared by ANOVA. RESULTS: Most facets had Cronbach's alpha above 0.60. Confirmatory factor analysis showed acceptable loading of the facets on their own hypothesized factors and very good estimations of Cronbach's alphas for the hypothesized factors, so it was partially supportive of the five-factor structure of the NEO-PI-3.The factors extracted with Procrustes rotation analysis can be considered reasonably homologous to the factors of the American normative sample. Correlations between dimensions were as expected and similar to those reported in the literature. DISCUSSION: The literature suggests that overall, the psychometric properties of NEO-PI-3 scales have been found to generalize across ages, cultures, and methods of measurement. In accord with this, the results of the current study confirm the reliability of the Greek translation and adaptation of the NEO-PI-3. The inventory has comparable psychometric properties in its Greek version in comparison to the original and other national translations, and it is suitable for clinical as well as research use

Implications of Polarized Pupil Degradation Due to Focal Shifts in Dynamically Ranged Rayleigh Beacons

A dynamically ranged pulsed Rayleigh beacon using sensed wavefronts across a system’s pupil plane is proposed for tomographic quantification of the atmospheric turbulence strength. This method relies on relaying light from a telescope system’s pupil plane to a wavefront sensor and having precise control of the light-blocking mechanisms to filter out scattered light from the unwanted scattering regions along the propagation path. To accomplish this, we tested and incorporated design features into the sensing system that we believe, to the best of our knowledge, are unique. Dynamically changing the range of the beacon source created focal shifts along the optical axis in the telescope sensing system. This effect induced polarization degradation in the optical pupil. As a result, polarization nonuniformity within the Pockels cell resulted in light leakages that corrupted the sensed data signals. To mitigate this unwanted effect, an analysis of the polarization pupil had to be completed for the range of possible Rayleigh beacon source distances, relating the change in polarization to the ability of a Pockels cell to function as an optical shutter. Based on the resultant polarization pupil analysis, careful design of the light relay architecture of the sensing system was necessary to properly capture sensed wavefront data from a series of intended ranges. Results are presented for the engineering design of the Turbulence and Aerosol Research Dynamic Interrogation System sensing system showing the choices made within the trade space and how those choices were made based on an analysis of the polarization pupil. Based on what we learned, recommendations are made to effectively implement a polarization-based Pockels cell shutter system as part of a dynamically ranged Rayleigh beacon system

An exploration of individual personality types in software development

Previous research - using conventional psychometric questionnaires - has highlighted the importance of aligning compatible personality types in software development teams. However, there does not exist a dedicated, robust questionnaire instrument for revealing the pertinent personality types for software development practitioners. This study analyzes the validity and reliability of a 70-item (context dependent) personality-profiling questionnaire particularly developed to assess personality types of software practitioners. A systematic process of validation, using an iterative approach to questionnaire development, was employed. The questions were developed both with a qualitative analysis of interview data, and based on the opinions of expert reviewers who revised the items through a set of examination. To investigate how stable the questions and reproducible the results, we measured test-retest reliability of the instrument, yielding satisfactory results. The present study provided evidence for the construct validity of the instrument. Ultimately, an initial comparison of the results delivered by the instrument demonstrated positive correlations with the findings acquired with well- known personality assessment instrument, i.e. the big five personality questionnaire