Integrating topographic, photogrammetric and laser scanning techniques for a scan-to-bim process

The preservation of historic buildings can often be particularly difficult due to the lack of detailed information about architectural features, construction details, etc.. However, in recent years considerable technological innovation in the field of Architecture, Engineering, and Construction (AEC) has been achieved by the Building Information Modeling (BIM) process. BIM was developed as a methodology used mainly for new construction but, given its considerable potential, this approach can also be successfully used for existing buildings, especially for buildings of historical and architectural value. In this case, it is more properly referred to as Historic - or Heritage - Building Information Modeling (HBIM). In the HBIM process, it is essential to precede the parametric modeling phase of the building with a detailed 3D survey that allows the acquisition of all geometric information. This methodology, called Scan-to-BIM, involves the use of 3D survey techniques for the production of point clouds as a geometric "database"for parametric modeling. The Scan-to-BIM approach can have several issues relating to the complexity of the survey. The work aims to apply the Scan-to-BIM approach to the survey and modeling of a historical and architectural valuable building to test a survey method, based on integrating different techniques (topography, photogrammetry and laser scanning), that improves the data acquisition phase. The "Real Cantina Borbonica"(Cellar of Royal House of Bourbon) in Partinico (Sicily, Italy) was chosen as a case study. The work has allowed achieving the HBIM of the "Real Cantina Borbonica"and testing an approach based exclusively on a topographic constraint to merge in the same reference system all the survey data (laser scanner and photogrammetric point clouds)

COVID-19 and the impact on the cranio-oro-facial trauma care in Italy: An epidemiological retrospective cohort study

The coronavirus disease 2019 (COVID-19) has deeply modified the organization of hospitals, health care centers, and the patient’s behavior. The aim of this epidemiological retrospective cohort study is to evaluate if and how the COVID-19 pandemic has determined a modification in cranio-oro-facial traumatology service. Methods: The dataset included hospital emergency room access of a six-month pre-pandemic period and six months into pandemic outbreak. The variables collected were: patient age, gender, type of emergency access with relative color code, Glasgow Coma Scale Score, type of discharge. Results: 537 vs 237 (pre-pandemic vs pandemic) patients accessed the hospital emergency room and the mean age decreased from 60.79 ± 25.34 to 56.75 ± 24.50 year. Yellow and green code access went from 28.9% and 66.1% to 37.5% and 57.7% (pre-pandemic vs pandemic). Glasgow Coma Scale (GCS) shows an increase of 16.6% vs 27.8% of 15 grade score, a 28.7% vs 28.5% of the 14 grade score and reduction of 13 and 12 grade 40.2% and 14.5% vs 37.1 and 9.7% (pre-pandemic vs pandemic). Conclusions: Since the COVID-19 outbreak continues, epidemiological data are still necessary to perform public health intervention strategies and to appropriately predict the population needs, in order to properly manage the COVID-19 related to oral pathologies as well as the most common health problems

Life Cycle Inventory (LCI) analysis of the Sicilian artistic and traditional ceramics as a tool for sustainable manufacturing

In the last few decades, greater attention is being paid by the Italian industrial ceramics sector to the environmental impacts related to ceramics production cycle and many companies have acquired voluntary environmental certifications (ISO 14001 or EMAS) or labeling (Ecolabel or EPD). This is not the case with the artistic ceramics sector in which few companies are certified. One of the most common and used tool for evaluating the environmental impact of products is the Life Cycle Assessment (LCA) methodology. This paper presents the preliminary results from a Life Cycle Inventory (LCI) analysis of the artistic ceramics sector in Caltagirone (Italy). Representative life cycle inventories are essential for any good quality LCA. They represent the fundamental blocks for compiling the full LCA of the ceramics production process, hence promoting environmental sustainability

Ecophysiological characterization of cultivable Antarctic psychrotolerant marine bacteria able to degrade hydrocarbons

The basic understanding of both the physiology and ecology of psychrotolerant Antarctic bacteria is a crucial step for the optimization of their biodegradative activity in cold environments. The detection of cold-adapted hydrocarbon-degrading bacteria in Antarctic seawaters is certainly of great interest for bioremediative purpose in oil polluted marine Antarctic systems, where the introduction of non native species is not allowed. This study focused on psychrotolerant marine bacteria inhabiting an Antarctic coastal area directly influenced by the human activity at the Italian Research Station (Terra Nova Bay). Fifty bacterial strains were isolated from hydrocarbon-degrading enrichment cultures obtained from seawater samples collected in the inlet Road Bay (Ross Sea). A preliminary Restriction Fragment Length Polymorphism (RFLP) analysis, carried out on 16S rDNA amplified via PCR using RSAI and AluI restriction enzymes, was applied to cluster the isolates according to the restriction profile they showed. One representative isolate per cluster was selected for further characterization; to elucidate their taxonomic position, conventional phenotypic and phylogenetic analyses were performed. Results led to the identification of the isolates as members of ten genera belonging to four phylogenetic groups: the alfa- and gamma-proteobacteria subdivisions, the gram-positive branch and the Cytophaga-Flexibacter-Bacteroides (CFB) phylum. Results indicate a high degree of biodiversity within the peculiar ecophysiological group of the hydrocarbon-degrading marine bacteria

Hereditary spastic paraplegia: Clinical-genetic characteristics and evolving molecular mechanisms

AbstractHereditary spastic paraplegia (HSP) is a group of clinically and genetically heterogeneous neurological disorders characterized by pathophysiologic hallmark of length-dependent distal axonal degeneration of the corticospinal tracts. The prominent features of this pathological condition are progressive spasticity and weakness of the lower limbs. To date, 72 spastic gait disease-loci and 55 spastic paraplegia genes (SPGs) have been identified. All modes of inheritance (autosomal dominant, autosomal recessive, and X-linked) have been described. Recently, a late onset spastic gait disorder with maternal trait of inheritance has been reported, as well as mutations in genes not yet classified as spastic gait disease. Several cellular processes are involved in its pathogenesis, such as membrane and axonal transport, endoplasmic reticulum membrane modeling and shaping, mitochondrial function, DNA repair, autophagy, and abnormalities in lipid metabolism and myelination processes. Moreover, recent evidences have been found about the impairment of endosome membrane trafficking in vesicle formation and about the involvement of oxidative stress and mtDNA polymorphisms in the onset of the disease. Interactome networks have been postulated by bioinformatics and biological analyses of spastic paraplegia genes, which would contribute to the development of new therapeutic approaches

Antarctic Salt-Cones: An Oasis of Microbial Life? The Example of Boulder Clay Glacier (Northern Victoria Land)

The evaporation of a localized, highly saline water body of the Boulder Clay debris-covered glacier, in the Northern Victoria Land, probably generated the accumulation of mirabilite (Na2SO4 × 10H2O) and thenardite (Na2SO4) in a glacier salt-cone. Such an extremely cold and salty environment resembles the conditions on Mars, so it can be considered a terrestrial analog. The study was aimed at gaining a first glimpse at the prokaryotic community associated with Antarctic mirabilite and thenardite minerals and also to find clues about the origin of the salts. For this purpose, samples were analyzed by a next generation approach to investigate the prokaryotic (Bacteria and Archaea) diversity. Phylogenetic analysis allowed the identification of Bacteroidota, Actinobacteriota, Firmicutes, and Gammaproteobacteria as the main bacterial lineages, in addition to Archaea in the phylum Halobacterota. The genera Arthrobacter, Rhodoglobus, Gillisia, Marinobacter and Psychrobacter were particularly abundant. Interestingly, several bacterial and archaeal sequences were related to halotolerant and halophilic genera, previously reported in a variety of marine environments and saline habitats, also in Antarctica. The analyzed salt community also included members that are believed to play a major role in the sulfur cycle

Italian immunization calendar implementation: Time to optimize number of vaccination appointments?

In the Italian vaccination schedule, at least six vaccination appointments are scheduled in the first year of life. This implies more discomfort for both the patient and the parents. This was particularly evident during the COVID-19 pandemic, during which several appointments were missed. A UK experience with three injectable vaccines and an oral one co-administered at the same appointment (4-in-1) at 2 and 4 months of age showed interesting results. The vaccination coverage was high, consistent with previous practice, and no relevant increase in adverse events was reported. Translating the UK experience into the Italian context would not be immediate, due to several organizational and social issues. Nevertheless, this option warrants some further considerations, which are discussed in this manuscript

First insights into the microbiology of three antarctic briny systems of the northern Victoria land

Different polar environments (lakes and glaciers), also in Antarctica, encapsulate brine pools characterized by a unique combination of extreme conditions, mainly in terms of high salinity and low temperature. Since 2014, we have been focusing our attention on the microbiology of brine pockets from three lakes in the Northern Victoria Land (NVL), lying in the Tarn Flat (TF) and Boulder Clay (BC) areas. The microbial communities have been analyzed for community structure by next generation sequencing, extracellular enzyme activities, metabolic potentials, and microbial abundances. In this study, we aim at reconsidering all available data to analyze the influence exerted by environmental parameters on the community composition and activities. Additionally, the prediction of metabolic functions was attempted by the phylogenetic investigation of communities by reconstruction of unobserved states (PICRUSt2) tool, highlighting that prokaryotic communities were presumably involved in methane metabolism, aromatic compound biodegradation, and organic compound (proteins, polysaccharides, and phosphates) decomposition. The analyzed cryoenvironments were different in terms of prokaryotic diversity, abundance, and retrieved metabolic pathways. By the analysis of DNA sequences, common operational taxonomic units ranged from 2.2% to 22.0%. The bacterial community was dominated by Bacteroidetes. In both BC and TF brines, sequences of the most thermally tolerant and methanogenic Archaea were detected, some of them related to hyperthermophiles