Voltammetric Determination of 5‐Aminoquinoline at Carbon Film Electrode and Carbon and Gold Screen Printed Electrodes – A Comparative Study

Aminoquinolines are widely used as antimalarial drugs and thus there is an ever increasing demand for their determination. In this paper, non-traditional carbon film electrode developed in our laboratory (CFE) with easily replaceable carbon film was used for the determination of 5-aminoquinoline (5-AQ) and compared with well-established commercially available carbon screen printed electrode (CSPE) and gold screen printed electrode (AuSPE). Electrochemical behavior of 5-AQ was characterized by cyclic and differential pulse voltammetry. Differences in electrochemical behavior of 5-AQ at different electrodes were evaluated. Determination of 5-AQ was carried out by differential pulse, square wave, and direct current voltammetry. Practical applicability of the method was verified by direct determination of 5-AQ in model samples of drinking and river water. Achieved limits of quantitation were in submicromolar concentrations. It was found out that novel CFE in terms of overall performance is in most aspects superior to routinely used commercially available CSPE and AuSPE