17,983 research outputs found
A platform for glycoengineering a polyvalent pneumococcal bioconjugate vaccine using E. coli as a host
The Fourth Positive System of Carbon Monoxide in the Hubble Space Telescope Spectra of Comets
The rich structure of the Fourth Positive System (A-X) of carbon monoxide
accounts for many of the spectral features seen in long slit HST-STIS
observations of comets 153P/Ikeya-Zhang, C/2001 Q4 (NEAT), and C/2000 WM1
(LINEAR), as well as in the HST-GHRS spectrum of comet C/1996 B2 Hyakutake. A
detailed CO fluorescence model is developed to derive the CO abundances in
these comets by simultaneously fitting all of the observed A-X bands. The model
includes the latest values for the oscillator strengths and state parameters,
and accounts for optical depth effects due to line overlap and self-absorption.
The model fits yield radial profiles of CO column density that are consistent
with a predominantly native source for all the comets observed by STIS. The
derived CO abundances relative to water in these comets span a wide range, from
0.44% for C/2000 WM1 (LINEAR), 7.2% for 153P/Ikeya-Zhang, 8.8% for C/2001 Q4
(NEAT) to 20.9% for C/1996 B2 (Hyakutake). The subtraction of the CO spectral
features using this model leads to the first identification of a molecular
hydrogen line pumped by solar HI Lyman-beta longward of 1200A in the spectrum
of comet 153P/Ikeya-Zhang. (Abridged)Comment: 12 pages, 11 figures, ApJ accepte
Manned Venus Flyby
This study is one of several being conducted at Bellcomm and in Manned Space Flight whose purpose is to give guidance to the Apollo Applications Program's technical objectives by focusing on a longer range goal. The assumed mission in this case is a three-man flyby of Venus launched in November, 1973 on a single standard Saturn V. The selected flight configuration includes a Command and Service Module similar in some respects to Apollo, an Environmental Support Module which occupies the adapter area and a spent S-IVB stage which is utilized for habitable volume and structural support of a solar cell electrical power system. The total injected weight, 106,775 lbs., is within the capability of a single Saturn V of the early 1970's. The study is focused on the selection of subsystem technologies appropriate to long duration flight. The conclusions are reported in terms of the technical characteristics to be achieved as part of the Apollo Applications Program's long duration objectives
Vortex Plasma in a Superconducting Film with Magnetic Dots
We consider a superconducting film, placed upon a magnetic dot array.
Magnetic moments of the dots are normal to the film and randomly oriented. We
determine how the concentration of the vortices in the film depends on the
magnetic moment of a dot at low temperatures. The concentration of the
vortices, bound to the dots, is proportional to the density of the dots and
depends on the magnetization of a dot in a step-like way. The concentration of
the unbound vortices oscillates about a value, proportional to the magnetic
moment of the dots. The period of the oscillations is equal to the width of a
step in the concentration of the bound vortices.Comment: RevTeX, 4 page
Can Drug Screening Lead to Candidate Therapies for Testing in Diabetic Neuropathy?
A key mechanism of dorsal root ganglia (DRG) neuron injury in high glucose is mitochondrial overload leading to oxidative stress. We screened selected compounds for the ability to prevent hyperglycemia-induced mitochondrial superoxide in primary sensory DRG neurons. Twenty five out of 1,040 compounds decreased both mitochondrial superoxide and subsequent neuronal injury. These data both validate our screening strategy and indicate further mechanistic evaluation of drug hits and related compounds. Such studies may lead to the design of rational therapeutic approaches for this severe complication of diabetes.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/63408/1/ars.2007.1815.pd
Reversibility of Serum Removal Effects on IGF-II mRNA in Human Neuroblastoma Cells
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73527/1/j.1749-6632.1993.tb26227.x.pd
Superoperator Analysis of Entanglement in a Four-Qubit Cluster State
In this paper we utilize superoperator formalism to explore the entanglement
evolution of four-qubit cluster states in a number of decohering environments.
A four-qubit cluster state is a resource for the performance of an arbitrary
single logical qubit rotation via measurement based cluster state quantum
computation. We are specifically interested in the relationship between
entanglement evolution and the fidelity with which the arbitrary single logical
qubit rotation can be implemented in the presence of decoherence as this will
have important experimental ramifications. We also note the exhibition of
entanglement sudden death (ESD) and ask how severely its onset affects the
utilization of the cluster state as a means of implementing an arbitrary single
logical qubit rotation.Comment: 9 pages, 9 composite figures, presentation of results completely
rewritte
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