92 research outputs found
DISTRIBUTED GENERATION IMPACT ON DISTRIBUTION NETWORKS: A REVIEW
The concept of traditional distribution networks with unidirectional power flow is weakening due to large penetration of Distributed Generation (DG). The penetration of DG may impact the operation of a distribution network in both beneficial and detrimental ways. Some of the positive impacts of DG are voltage support, power loss reduction, support of ancillary services and improved reliability, whereas negative ones include protection coordination, dynamic stability and islanding. Therefore, proper planning methods that evaluate the composite impacts, i.e. technical, economical and environmental impacts of DG integration to existing distribution networks are very much essential. This paper presents a critical review of various impacts of DG on power distribution system. For ease of reference and to facilitate better understanding this literature is categorized and discussed under five major headings
UK survey of occupational therapist’s and physiotherapist’s experiences and attitudes towards hip replacement precautions and equipment
Background: Total hip replacement (THR) is one of the most common orthopaedic procedures in the United Kingdom (UK). Historically, people following THR have been provided with hip precautions and equipment such as: raised toilet seats and furniture rises, in order to reduce the risks of dislocation post-operation. The purpose of this study was to determine current practices in the provision of these interventions in the UK for people following primary THR. Methods: A 27-question, self-administered online survey was developed and distributed to UK physiotherapists and occupational therapists involved in the management of people following primary THR (target respondents). The survey included questions regarding the current practices in the provision of equipment and hip precautions for THR patients, and physiotherapist’s and occupational therapist’s attitudes towards these practices. The survey was disseminated through print and web-based/social media channels. Results: 170 health professionals (87 physiotherapists and 83 occupational therapists), responded to the survey. Commonly prescribed equipment in respondent’s health trusts were raised toilet seats (95%), toilet frames and rails (88%), furniture raises (79%), helping hands/grabbers (77%), perching stools (75%) and long-handled shoe horns (75%). Hip precautions were routinely prescribed by 97% of respondents. Hip precautions were most frequently taught in a pre-operative group (52% of respondents). Similarly equipment was most frequently provided pre-operatively (61% respondents), and most commonly by occupational therapists (74% respondents). There was variability in the advice provided on the duration of hip precautions and equipment from up to six weeks post-operatively to life-time usage. Conclusions: Current practice on hip precautions and provision of equipment is not full representative of clinician’s perceptions of best care after THR. Future research is warranted to determine whether and to whom hip precautions and equipment should be prescribed post-THR as opposed to the current ‘blanket’ provision of equipment and movement restriction provided in UK practice
Temporal Effects of Cyclic Stretching on Distribution and Gene Expression of Integrin and Cytoskeleton by Ligament Fibroblasts In Vitro
Cyclic stretching is pivotal to maintenance of the ligaments. However, it is still not clear when ligament fibroblasts switch on expression of genes related to the mechanotransduction pathway in response to cyclic stretching. This in vitro study investigated, using ligament fibroblasts, the time-dependent changes in distribution and gene expression of β1 integrin, the cytoskeleton, and collagens after the application of 6% cyclic stretching at a frequency of 0.1 Hz for 3 hr on silicon membranes. We carried out confocal laser scanning microscopy to demonstrate changes in distribution of these components as well as quantitative real-time RT-PCR to quantify levels of these gene expression both during application of cyclic stretching and at 0, 2, 6, 12, and 18 hr after the termination of stretching. Control (unstretched) cells were used at each time point. Within 1 hr of the application of stretching, the fibroblasts and their actin stress fibers became aligned in a direction perpendicular to the major axis of stretch, whereas control (unstretched) cells were randomly distributed. In response to cyclic stretching, upregulation of actin at the mRNA level was first observed within 1 hr after the onset of stretching, while upregulation of β1 integrin and type I and type III collagens was observed between 2 and 12 hr after the termination of stretching. These results indicate that the fibroblasts quickly modify their morphology in response to cyclic stretching, and subsequently they upregulate the expression of genes related to the mechanotransduction pathway mainly during the resting period after the termination of stretching
Fluid lavage in patients with open fracture wounds (FLOW): an international survey of 984 surgeons
<p>Abstract</p> <p>Background</p> <p>Although surgeons acknowledge the importance of irrigating open fracture wounds, the choice of irrigating fluid and delivery pressure remains controversial. Our objective was to clarify current opinion with regard to the irrigation of open fracture wounds.</p> <p>Methods</p> <p>We used a cross-sectional survey and a sample-to-redundancy strategy to examine surgeons' preferences in the initial management of open fracture wounds. We mailed this survey to members of the Canadian Orthopaedic Association and delivered it to attendees of an international fracture course (AO, Davos, Switzerland).</p> <p>Results</p> <p>Of the 1,764 surgeons who received the questionnaire, 984 (55.8%) responded. In the management of open wounds, the majority of surgeons surveyed, 676 (70.5%), favoured normal saline alone. Bacitracin solution was used routinely by only 161 surgeons (16.8%). The majority of surgeons, 695 (71%) used low pressures when delivering the irrigating solution to the wound. There was, however considerable variation in what pressures constituted high versus low pressure lavage. The overwhelming majority of surgeons, 889 (94.2%), reported they would change their practice if a large randomized controlled trial showed a clear benefit of an irrigating solution – especially if it was different from the solution they used.</p> <p>Conclusion</p> <p>The majority of surgeons favour both normal saline and low pressure lavage for the initial management of open fracture wounds. However, opinions varied as regards the comparative efficacy of different solutions, the use of additives and high versus low pressure. Surgeons have expressed considerable support for a trial evaluating both irrigating solutions and pressures.</p
G × E interactions in QTL introgression lines of Spanish-type groundnut (Arachis hypogaea L.)
Multi-environment testing at five locations
for rust and late leaf spot (LLS) resistance with
41 introgressed lines (ILs) bred using marker-assisted
backcross breeding in the genetic background Spanish-
type groundnut varieties identified significant
genotype, and genotype 9 environment interactions
(GEI) for LLS disease resistance and yield parameters.
Significant GEI effects suggest the need to identify location specific breeding lines to achieve gains in pod
yield and LLS resistance. The observed variable LLS
disease reaction among the ILs in part suggests
influence of background genotype on the level of
resistance. A breeding scheme with early generation
selection using molecular markers followed by phenotyping
for LLS, and multi-location testing of fixed
breeding lines was optimized to enhance selection
intensity and accuracy in groundnut breeding. The ILs,
ICGVs 14431, 14436 and 14438 with pooled LLS
score at 90 DAS of 3.5–3.7 were superior to respective
recurrent parent for pod yield, with early maturing
similar to recurrent parents. The pod yield advantage in ILs is attributed by more number of pods, besides
resistance to LLS that contributes to better filling
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