A Review of the Potential Benefits of Plants Producing Berries in Skin Disorders

During the last 30 years, berries have gained great attention as functional food against several risk factors in chronic diseases. The number of related publications on Pubmed rose from 1000 items in 1990 to more than 11,000 in 2019. Despite the fact that a common and clear definition of "berries" is not shared among different scientific areas, the phytochemical pattern of these fruits is mainly characterized by anthocyanins, flavanols, flavonols, and tannins, which showed antioxidant and anti-inflammatory properties in humans. Skin insults, like wounds, UV rays, and excessive inflammatory responses, may lead to chronic dermatological disorders, conditions often characterized by long-term treatments. The application of berries for skin protection is sustained by long traditional use, but many observations still require a clear pharmacological validation. This review summarizes the scientific evidence, published on EMBASE, MEDLINE, and Scholar, to identify extraction methods, way of administration, dose, and mechanism of action of berries for potential dermatological treatments. Promising in vitro and in vivo evidence of Punica granatum L. and Vitis vinifera L. supports wound healing and photoprotection, while Schisandra chinensis (Turcz.) Baill. and Vaccinium spp. showed clear immunomodulatory effects. Oral or topical administrations of these berries justify the evaluation of new translational studies to validate their efficacy in humans

Rhus coriaria l. Fruit extract prevents UV-A-induced genotoxicity and oxidative injury in human microvascular endothelial cells

Rhus coriaria L. (sumac) is a small plant widely diffused in the Mediterranean region. Its fruit are often consumed as a spice but are also present in traditional medicine of several countries. Recently, interest in this plant has increased and many scientific works reported its beneficial effects including antioxidant and anti-inflammatory properties. Plant extracts can be successfully used against ultraviolet rays, which are able to reach and damage the human skin; however, sumac extracts were never applied to this usage. Thus, in this study, we used a macerated ethanol extract of Rhus coriaria L. dried fruit (mERC) to demonstrate its preventive role against the damage induced by ultraviolet-A rays (UV-A) on microvascular endothelial cells (HMEC-1). In vitro effects of the extract pre-treatment and UV-A exposure were evaluated in detail. The antioxidant capacity was assessed by reactive oxygen species (ROS) formation and cellular antioxidant activity measurement. Genoprotective effects of mERC were investigated as well. Our findings indicate that the extract acts as a cell cycle inhibitor or apoptosis inducer, according to the level of damage. The present work provides new insights into the usage of Rhus coriaria extracts against skin injuries

Guest editorial: Application of cloud energy storage systems in power systems

Cloud energy storage system (CESS) technology is a novel idea to eliminate the distributed energy storage systems from the consumers into a cloud service centre, where CESS acts as a virtual energy storage capacity instead of the actual devices. The power and energy of several distributed energy storages are combined using a CESS to assure providing storage services for small consumers. A CESS is a shared pool of grid-scale energy storage systems to reduce the cost of energy storage services in the power system which can increase the penetration level of onsite distributed renewable energy sources, reduce the electricity bills of consumers, and provide flexibility to the power grid by reducing the peak loads. The current Special Issue aims to explore technologies, methodologies, and solutions to develop CESSs with an efficient, secure, and stable operation of power systems.Scopu

Neuroprotective and anti-inflammatory effects of Rhus coriaria extract in a mouse model of ischemic optic neuropathy

Modulating oxidative stresses and inflammation can potentially prevent or alleviate the pathological conditions of diseases associated with the nervous system, including ischemic optic neuropathy. In this study we evaluated the anti-neuroinflammatory and neuroprotective activities of Rhus coriaria (R. coriaria) extract in vivo. The half maximal inhibitory concentration (IC50) for DPPH, ABTS and \u3b2-carotene were 6.79 \ub1 0.009 \u3bcg/mL, 10.94 \ub1 0.09 \u3bcg/mL, and 6.25 \ub1 0.06 \u3bcg/mL, respectively. Retinal ischemia was induced by optic nerve crush injury in albino Balb/c mice. The anti-inflammatory activity of ethanolic extract of R. coriaria (ERC) and linoleic acid (LA) on ocular ischemia was monitored using Fluorescence Molecular Tomography (FMT). Following optic nerve crush injury, the mice treated with 400 mg/kg of ERC and LA exhibited an 84.87% and 86.71% reduction of fluorescent signal (cathepsin activity) respectively. The results of this study provide strong scientific evidence for the neuroprotective activity of the ERC, identifying LA as one of the main components responsible for the effect. ERC may be useful and worthy of further development for its adjunctive utilization in the treatment of optic neuropathy

Multi-criteria location identification for wind/solar based hydrogen generation: The case of capital cities of a developing country

© 2020 Hydrogen Energy Publications LLC The identification of site location is one of the critical tasks in developing or expanding any supply chain system including the construction of renewable power generation plants. The accurate identification of a plant site can considerably reduce unforeseen risks and costs and also raise productivity and efficacy. As such, this study sought to thoroughly evaluate all capital cities of a developing country for the establishment of a hybrid wind/solar power plant to produce hydrogen while considering the most influential and conflicting criteria. For this, 14 criteria including daily solar radiation, wind power density, clearness index, altitude, population, average sunny hours in a year, unemployment rate, average air temperature, average air humidity, average yearly precipitation, natural disasters, the distance between the site and the main road, average dusty days per year, and land price constituted the set of vital factors. To prioritize alternatives, a Fuzzy Multi-Criteria Decision Making approach named FVIKOR (Fuzzy Multi-Criteria Optimization and Compromise Solution) was used. The results indicated that among 31 capital cities, the city of Yazd with a wind power density of 309.5 W/m2 and daily solar radiation of 5.4 kWh/m2 would be the best location for the purpose of this study. To validate the findings, FTOPSIS (Fuzzy Technique for Order Preference by Similarity to Ideal Solution) method was utilized and it also ranked Yazd as the first option. Then, a sensitivity analysis was conducted to discern the behavior of each criterion and their impact on the ranking of the cities. Finally, for hydrogen generation, an autonomous hybrid wind/solar system was techno-economically assessed using HOMER software. According to the analysis outcome, the proposed system showed a payback period of 7 years with levelized cost of 4.75 $/kg for hydrogen