Maternal Cardiovascular Impairment in Pregnancies Complicated by Severe Fetal Growth Restriction

Abstract—Fetal growth restriction and preeclampsia are both conditions of placental etiology and associated to increased risk for the long-term development of cardiovascular disease in the mother. At presentation, preeclampsia is associated with maternal global diastolic dysfunction, which is determined, at least in part, by increased afterload and myocardial stiffness. The aim of this study is to test the hypothesis that women with normotensive fetal growth-restricted pregnancies also exhibit global diastolic dysfunction. This was a prospective case-control study conducted over a 3-year period involving 29 preterm fetal growth-restricted pregnancies, 25 preeclamptic with fetal growth restriction pregnancies, and 58 matched control pregnancies. Women were assessed by conventional echocardiography and tissue Doppler imaging at diagnosis of the complication and followed-up at 12 weeks postpartum. Fetal growth-restricted pregnancies are characterized by a lower cardiac index and higher total vascular resistance index than expected for gestation. Compared with controls, fetal growth-restricted pregnancy was associated with significantly increased prevalence (P�0.001) of asymptomatic left ventricular diastolic dysfunction (28% versus 4%) and widespread impaired myocardial relaxation (59% versus 21%). Unlike preeclampsia, cardiac geometry and intrinsic myocardial contractility were preserved in fetal growth-restricted pregnancy. Fetal growth-restricted pregnancies are characterized by a low output, high resistance circulatory state, as well as a higher prevalence of asymptomatic global diastolic dysfunction and poor cardiac reserve. These findings may explain the increased long-term cardiovascular risk in these women who have had fetal growth-restricted pregnancies. Further studies are needed to clarify the postnatal natural history of cardiac dysfunction in these women

Crossover from Fermi Liquid to Non-Fermi Liquid Behavior in a Solvable One-Dimensional Model

We consider a quantum moany-body problem in one-dimension described by a Jastrow type, characterized by an exponent $\lambda$ and a parameter $\gamma$. We show that with increasing $\gamma$, the Fermi Liquid state ($\gamma=0)$ crosses over to non-Fermi liquid states, characterized by effective "temperature".Comment: 8pp. late

Thermalization of acoustic excitations in a strongly interacting one-dimensional quantum liquid

We study inelastic decay of bosonic excitations in a Luttinger liquid. In a model with linear excitation spectrum the decay rate diverges. We show that this difficulty is resolved when the interaction between constituent particles is strong, and the excitation spectrum is nonlinear. Although at low energies the nonlinearity is weak, it regularizes the divergence in the decay rate. We develop a theoretical description of the approach of the system to thermal equilibrium. The typical relaxation rate scales as the fifth power of temperature

The thermodynamic limit for fractional exclusion statistics

I discuss Haldane's concept of generalised exclusion statistics (Phys. Rev. Lett. {\bf 67}, 937, 1991) and I show that it leads to inconsistencies in the calculation of the particle distribution that maximizes the partition function. These inconsistencies appear when mutual exclusion statistics is manifested between different subspecies of particles in the system. In order to eliminate these inconsistencies, I introduce new mutual exclusion statistics parameters, which are proportional to the dimension of the Hilbert sub-space on which they act. These new definitions lead to properly defined particle distributions and thermodynamic properties. In another paper (arXiv:0710.0728) I show that fractional exclusion statistics manifested in general systems with interaction have these, physically consistent, statistics parameters.Comment: 8 page

Supersymmetry, Shape Invariance and Solvability of AN−1A_{N-1} and BCNBC_{N} Calogero-Sutherland Model

Using the ideas of supersymmetry and shape invariance we re-derive the spectrum of the $A_{N-1}$ and $BC_N$ Calogero-Sutherland model. We briefly discuss as to how to obtain the corresponding eigenfunctions. We also discuss the difficulties involved in extending this approach to the trigonometric models.Comment: 15 pages, REVTeX,No figure

Exact Solution of Heisenberg-liquid models with long-range coupling

We present the exact solution of two Heisenberg-liquid models of particles with arbitrary spin $S$ interacting via a hyperbolic long-range potential. In one model the spin-spin coupling has the simple antiferromagnetic Heisenberg exchange form, while for the other model the interaction is of the ferromagnetic Babujian-Takhatajan type. It is found that the Bethe ansatz equations of these models have a similar structure to that of the Babujian-Takhatajan spin chain. We also conjecture the integrability of a third new spin-lattice model with long-range interaction.Comment: 7pages Revte

Some Properties of the Calogero-Sutherland Model with Reflections

We prove that the Calogero-Sutherland Model with reflections (the BC_N model) possesses a property of duality relating the eigenfunctions of two Hamiltonians with different coupling constants. We obtain a generating function for their polynomial eigenfunctions, the generalized Jacobi polynomials. The symmetry of the wave-functions for certain particular cases (associated to the root systems of the classical Lie groups B_N, C_N and D_N) is also discussed.Comment: 16 pages, harvmac.te

Lower limb cellulitis: low diagnostic accuracy and underdiagnosis of risk factors

Accurate diagnosis and recognition of predisposing factors has been shown to be challenging in lower limb cellulitis. Assessment of 1746 consecutive cellulitis patients presenting to a UK university hospital showed increasing overdiagnosis with only 31.9% of referred patients with confirmed lower-limb cellulitis between 2015-2018. Recognition of at least one predisposing factor increased from 61% to 89% following introduction of more specific screening questions. This identified a need for better primary care dermatology education and the benefit of a proforma with specific screening questions for reversible predisposing factors for lower limb cellulitis. This article is protected by copyright. All rights reserved

Self-similarity and novel sample-length-dependence of conductance in quasiperiodic lateral magnetic superlattices

We study the transport of electrons in a Fibonacci magnetic superlattice produced on a two-dimensional electron gas modulated by parallel magnetic field stripes arranged in a Fibonacci sequence. Both the transmission coefficient and conductance exhibit self-similarity and the six-circle property. The presence of extended states yields a finite conductivity at infinite length, that may be detected as an abrupt change in the conductance as the Fermi energy is varied, much as a metal-insulator transition. This is a unique feature of transport in this new kind of structure, arising from its inherent two-dimensional nature.Comment: 9 pages, 5 figures, revtex, important revisions made. to be published in Phys. Rev.