ARTIFICIAL INTELLIGENCE AND PARTICLE SWARM OPTIMIZATION ALGORITHM FOR OPTIMIZATION PROBLEM IN MICROGRIDS

The modern heuristic techniques mainly include the application of the artificial intelligence approaches such as genetic algorithm, particle swarmoptimization algorithm, ant colony optimization, stochastic diffusion search, differential evolution, etc. The main aspect of these techniques is theirflexibility for solving the optimization problems that have different mathematical constraints. In a power system area, the competition between theelectric utilities is gradually increased due to the deregulation of the electrical markets. For this reason, the generation expansion problem presentsitself as an important issue that needs to be considered in order to achieve reasonable economic decisions.Keywords: Genetic algorithm, Particle swarm optimization, Artificial intelligence

Comparative observational study between Atorvastatin and Rosuvastatin based on HbA1c levels of patients diagnosed with acute coronary syndrome and heart failure

Background: Our study aims to compare HbA1c levels in hospitalized acute coronary syndrome and heart failure patients treated with atorvastatin versus rosuvastatin Methods: This is a retrospective, prospective  observational study in which the study population includes ACS and HF Hospitalized patients, the study subjects are divided based on patients prescribed  with Atorvastatin and Rosuvastatin based on the medication chart, and those patients' previous history of statin use is collected from history chart, patient case notes, doctors notes, laboratory data is collected and documented in data collection form, lab data includes HbA1c, finally compared Atorvastatin and Rosuvastatin using excel and JASP descriptive analysis. Results: Overall, we collected data for 132 cases, of which 55% are males and 45% females, 59.10% are above 61 years of age, 39.39% are diagnosed with ACS and 23.48% are diagnosed with HF, among 67 patients who are using Atorvastatin, there was a significant mean decrease in HbA1c% from 8.359% to 7.901%, and among 65 Rosuvastatin users there was an increase in mean HbA1c% from 8.386%  to 8.389%. Additionally for non-diabetic individuals, there was an increase in Hba1c% from 6.339% to 6.387%. Conclusions: We concluded that Atorvastatin is a more effective statin than Rosuvastatin which will reduce the risk of new-onset Diabetes Mellitus in non- diabetic individuals and reduce the risk of increasing complications of diabetes mellitus in patients who are Diabetic

A study on drug utilization pattern of anticoagulants in post-cardiac surgeries at a tertiary care hospital

Background: The study is being carried out mainly to understand the prevention of coagulation of blood after a patient undergoing various types of cardiac surgeries, using different anticoagulation therapies suitable to particular types of cardiac surgery. This study was conducted to know the types of anticoagulants prescribed to patients who have undergone different types of cardiac surgeries along with the prescribed anticoagulants. Methods: The study method used was a retrospective and prospective observational study carried out on 50 patients who underwent cardiac surgeries in the department of cardiology and medicine. Results: A total of 50 patients were enrolled for this study who satisfied the inclusion criteria, out of which 64% of patients were males, and 36% were females. The highest number of patients were found to be in between the age group of 61-70 yrs (34%), whereas age group between 51-60 yrs (28%), age group 71 and above (18%), 41-50 (14%), 21-30 yrs (4%) and 18-20 yrs (2%) respectively. Most of the patients had undergone Coronary Artery bypass grafting. It was seen that the highest Anticoagulant being prescribed was Heparin in most of the post-cardiac surgeries. Whereas drugs like dalteparin, acenocoumarol, and warfarin were prescribed the majority in valvular heart surgeries. Conclusions: Various cardiac surgeries were taken into consideration for the study. The most common anticoagulants prescribed were heparin, dalteparin, acenocoumarol, and warfarin in coronary artery bypass surgery and valvular heart surgeries respectively

Seroma: an interesting case report

A seroma is defined as a sterile accumulation of serum in a circumscribed location in the tissue. Seromas can occur after surgeries, especially those that are extensive or involve significant tissue disruption viz. hernia repairs, plastic surgeries such as breast augmentation or reconstruction, abdominoplasties (tummy tucks)and removal of large intra-abdominal space occupying lesions like huge fibroids/ovarian masses. The literature citing the exact incidence of seromas following removal of large intra-abdominal masses is scant. Seromas at times become severely symptomatic. The best way to prevent a seroma is not to give it any place to form. It's easier said than done. Here is an interesting case report of postoperative seroma following removal of a large broad ligament fibroid

Intrauterine insemination: a retrospective review on determinants of success

Background: To determine the prognostic factors such as female patient’s characteristics and of semen parameters on the pregnancy rate following intrauterine inseminationMethods: This study was done at Assisted Reproduction Centre, KLE’s Hospital and Medical Research Centre, Belgaum, India between June 2011 to May 2012. A total of 264 IUI cycles in which clomiphene citrate with or without human menopausal gonadotropin was used for ovarian stimulation were analysed retrospectively to identify prognostic factors regarding treatment outcome.Results: In this study the pregnancy rate was 17.25%. The logistic regression analysis of variables showed that number of follicles and total IUI cycles were significantly associated with success rate but age of the couple, duration of infertility, endometrial thickness, size of the follicles, sperm count and sperm motility did not show significant differences between pregnant and non pregnant women.Conclusions: The findings of this study showed that age of the couple, duration of infertility, endometrial thickness, size of the follicles, sperm count and sperm motility did not correlate with pregnancy occurrence in an IUI cycle but number of follicles and total IUI cycles correlated with the occurrence of pregnancy.

Studies on the Energy Band Discontinuities in SnS/ZnMgO Thin Film Heterojunction

AbstractTin sulfide (SnS), with a direct energy band gap of 1.3eV and high absorption coefficient >104cm-1 is a promising candidate for application as an absorber material for solar cell fabrication. Although several research groups have fabricated SnS-related solar cells, the reported efficiencies were low (< 3.0%). One of the reasons for this low efficiency is the mismatch at the band edges in the heterojunction. In the present work, SnS films have been synthesized by sulfurization of Sn layers deposited by evaporation and RF sputtering onto SnO2 coated glass. The structural properties of the layers were discussed. All RF sputtered Zn0.8Mg0.2O (ZMO) and ZnO:Ga were coated on SnS as buffer and window layers respectively. The band offsets at the SnO2/SnS and ZMO/SnS heterojunctions were evaluated using X-ray photoelectron spectroscopy measurements. The conduction band (ΔEc) and valence band (ΔEv) discontinuities were determined as approximately 1.0eV and 3.5eV for SnO2/SnS and 0.4eV and 1.7eV for ZMO/SnS junction. The related energy band diagram was constructed and the results discussed

EVALUATION OF THE PROPHYLACTIC ROLE OF INDIAN SHRIMP IN ALUMINUM CHLORIDE-INDUCED ALZHEIMER’S DISEASE ON EXPERIMENTAL RATS

Objective: This work was aimed to investigate the prophylactic and therapeutic role of Indian shrimp in aluminum chloride-induced Alzheimer’s disease (AD) in rats. Methods: The male Wistar rats were selected and divided into six groups. Group I received distilled water, Group II received AlCl3 ( 100 mg/kg, p.o.), Group III received rivastigmine (1 mg/kg, p.o.), Group IV received AlCl3 + shrimp powder (200 mg/kg, p.o), and Group V received AlCl3 + shrimp powder (400 mg/kg, p.o) for 60 days. At the end of the study, various parameters such as behavioral and biochemical investigations were assessed. Results: The result of the study shows that the shrimp (400 mg/kg) has better effect on the treatment of aluminum chloride-induced AD in rats. It showed a remarkable improvement in the behavioral and biochemical parameters, and the result of histopathology study shows that the hippocampus region of brain tissue recovered as compared with control. Conclusion: From this study, it is evident that dietary intake of shrimp can help to inhibit oxidative stress produced due to the accumulation of AlCl3 in the brain and used as a prophylactic for AD

Plasmepsin inhibitors: design, synthesis, inhibitory studies and crystal structure analysis

Plasmepsin group of enzymes are key enzymes in the life cycle of malarial parasites. As inhibition of plasmepsins leads to the parasite's death, these enzymes can be utilized as potential drug targets. Although many drugs are available, it has been observed that Plasmodium falciparum, the species that causes most of the malarial infections and subsequent death, has developed resistance against most of the drugs. Based on the cleavage sites of hemglobin, the substrate for plasmepsins, we have designed two compounds (p-nitrobenzoyl-leucine-β -alanine and p-nitrobenzoyl-leucine-isonipecotic acid), synthesized them, solved their crystal structures and studied their inhibitory effect using experimental and theoretical (docking) methods. In this paper, we discuss the synthesis, crystal structures and inhibitory nature of these two compounds which have a potential to inhibit plasmepsins

Acanthopagrus berda - a potential species for mariculture in India

Sea breams belonging to the sparidae familyare excellent food fishes and important candidate species for aquaculture. Globally, the river bream, Acanthopagrus berda is highly valued in commercial fisheries and aquaculture due to their excellent meat quality, market demand, easy adaptability to captivity and ability to tolerate wide variations in both salinity and temperature. A. berda is distributed in the estuarine and shallow coastal waters of Kerala, Tamil Nadu, Andhra Pradesh, Maharashtra and Gujarat coasts (Fig.1). Locally known as “Karuthaeri” along Kerala coast they are fished by artisanal fishers using cast nets and hook & line and fetch ` 400-500 per kg in the domestic markets. At present, India is looking for native food fishes for mariculture development and A. berda is considered as a priority species due to their high market demand