Soluble CD40 ligand and prolactin levels in migraine patients during interictal period

The relationship of migraine with cardiovascular diseases has been clarified by many studies, and currently, migraine is suggested to be a systematic vasculopathy. Inflammation, thrombosis and impaired vascular reactivity are the underlying pathophysiological mechanisms of the vasculopathy. In the present study, we aimed to investigate the relationship between prolactin levels and subclinical atherosclerosis risk factors such as soluble CD40 ligand (sCD40L) and high-sensitivity CRP (hsCRP) in migraine patients during interictal period. Fifty female migraine patients and age-matched 25 female control cases were enrolled in the study. Migraine diagnosis was settled according to the ICHD-II diagnostic criteria. A questionnaire was completed about the existence of vascular risk factors. Serum samples were used to measure sCD40L, hsCRP and prolactin levels. No difference was found between the prolactin levels of the migraine patients and the controls. The sCD40L levels were significantly higher in migraine patients (p < 0.001). High-sensitivity CRP levels showed no difference between the groups. There was no correlation between prolactin, sCD40L, and hs-CRP levels in migraine patients. We consider that the migraine patients are prone to subclinical atherosclerosis, but this tendency is independent of prolactin levels

Fatty Acids, alpha-Tocopherol and Proximate Composition of Four Red Macroalgae in the Sinop Bay (Turkey)

WOS: 000321389100006The present investigation was to study the nutritional value, fatty acid composition and a-tocopherol of the red macroalgae Rhodophyta (Antithamnion, Ceramium, Corallina and Laurencia sp.) in the Sinop Bay from Black Sea. The highest level of 20:5 (n-3) was 27.18% of Dry Weight (DW) for Antithamnion sp., however, the lowest level was 11.90% DW for Ceramium sp. The alpha-tocopherol content in samples showed marked variation among the four types of algae and it was max; 21.2 +/- 0.2 and min; 8.5 +/- 0.3 mu g g(-1) DW. The highest level of total carotenoids was determined in the Antithamnion sp., contained as 1.69 +/- 0.46 mu g g(-1) DW. Nevertheless, the highest level of chlorophyll a was observed in the Laurencia sp. (0.26 +/- 0.01 mu g g(-1)). The crude protein content of the Antithamnion sp. (28.1 +/- 0.3%) and Ceramium sp. (28.5 +/- 0.5%) was higher than the Corallina and Laurencia sp. As a result, Antithamnion sp., is a good source of lipids with a good level of EPA, total carotenoids and alpha-tocopherol and Ceramum sp., evidenced to be an excellent protein source. In Europe, the development of novel foods, such as functional foods could be a new possibility for the use of these macroalgae, especially for the protein, fatty acids and alpha-tocopherol-rich species in human nutrition This present study results showed that these red macroalgae in the Sinop Bay could be utilized as functional ingredients for the valuable nutritional properties for seafood industries

Comprehensive Trauma Patient Care By Nonphysician Providers.

Nonphysician providers are being increasingly used to care for trauma patients. As these complex patients recover, they require meticulous medical management and time-consuming psychosocial care. A retrospective evaluation of a unique patient care service staffed by nonphysician providers is presented. The Intermediate Care Service is designed to facilitate the management and long-term placement of trauma patients who no longer require intensive care while recovering from their injuries. The new diagnoses, physician order changes, and disposition of 93 patients cared for during a 6-month period are described. Most patients were admitted with neurologic injury. The most common new diagnosis was constipation; the most frequent new orders related to medications, including bowel management, and rehabilitation consultations. All patients were discharged from the hospital. The Intermediate Care Service represents a unique and valuable model for the collaborative management of complex trauma patients

Fatty Acids, alpha-Tocopherol and Proximate Composition of Four Red Macroalgae in the Sinop Bay (Turkey)

WOS: 000321389100006The present investigation was to study the nutritional value, fatty acid composition and a-tocopherol of the red macroalgae Rhodophyta (Antithamnion, Ceramium, Corallina and Laurencia sp.) in the Sinop Bay from Black Sea. The highest level of 20:5 (n-3) was 27.18% of Dry Weight (DW) for Antithamnion sp., however, the lowest level was 11.90% DW for Ceramium sp. The alpha-tocopherol content in samples showed marked variation among the four types of algae and it was max; 21.2 +/- 0.2 and min; 8.5 +/- 0.3 mu g g(-1) DW. The highest level of total carotenoids was determined in the Antithamnion sp., contained as 1.69 +/- 0.46 mu g g(-1) DW. Nevertheless, the highest level of chlorophyll a was observed in the Laurencia sp. (0.26 +/- 0.01 mu g g(-1)). The crude protein content of the Antithamnion sp. (28.1 +/- 0.3%) and Ceramium sp. (28.5 +/- 0.5%) was higher than the Corallina and Laurencia sp. As a result, Antithamnion sp., is a good source of lipids with a good level of EPA, total carotenoids and alpha-tocopherol and Ceramum sp., evidenced to be an excellent protein source. In Europe, the development of novel foods, such as functional foods could be a new possibility for the use of these macroalgae, especially for the protein, fatty acids and alpha-tocopherol-rich species in human nutrition This present study results showed that these red macroalgae in the Sinop Bay could be utilized as functional ingredients for the valuable nutritional properties for seafood industries

Etnische diversiteit in docententeams in het hbo

Het hbo leidt professionals op die gaan werken in een multiculturele en internationale samenleving. Om de studenten hierop voor te bereiden is het van belang dat docenten beschikken over multiculturele competenties, en dat zij verbindingen weten te leggen tussen studenten met verschillende achtergronden. Docenten staan daarin niet alleen, ze kunnen terugvallen op hun team. In dit onderzoek wordt aan de hand van de ervaringen van 10 onderwijsteams, afkomstig van 5 verschillende hogescholen, beschreven hoe dat in zijn werk gaat

Exploring First Grade Medical Students’ Professional Identity Using Metaphors: Implications For Medical Curricula

Background Although professional identity development is an important concept in medical education, the process has not been well-investigated from a student perspective. Purpose This study examines the metaphorical images formulated by first grade medical students in Turkey to describe physicians in the context of establishing a professional identity, along with its limitations. Method Participants (N=148) completed the prompt: A physician is like _____ because _____ to indicate their conceptualizations of physician. The data were analyzed both qualitatively and quantitatively. Results Altogether, 71 well-articulated metaphorical images were identified – comprising six conceptual themes. Conclusions While subject to some limitations, the use of metaphors to formulate and describe professional identities can be helpful in reflecting the personal beliefs and values of matriculants to medical school, as well as providing some guidance and feedback to curriculum development efforts.PubMedWoSScopu