168 research outputs found
A Methodology for the Diagnostic of Aircraft Engine Based on Indicators Aggregation
Aircraft engine manufacturers collect large amount of engine related data
during flights. These data are used to detect anomalies in the engines in order
to help companies optimize their maintenance costs. This article introduces and
studies a generic methodology that allows one to build automatic early signs of
anomaly detection in a way that is understandable by human operators who make
the final maintenance decision. The main idea of the method is to generate a
very large number of binary indicators based on parametric anomaly scores
designed by experts, complemented by simple aggregations of those scores. The
best indicators are selected via a classical forward scheme, leading to a much
reduced number of indicators that are tuned to a data set. We illustrate the
interest of the method on simulated data which contain realistic early signs of
anomalies.Comment: Proceedings of the 14th Industrial Conference, ICDM 2014, St.
Petersburg : Russian Federation (2014
Health-related physical fitness of adolescents and young adults with myelomeningocele
To assess components of health-related physical fitness in adolescents and young adults with myelomeningocele (MMC), and to study relations between aerobic capacity and other health-related physical fitness components. This cross-sectional study included 50 adolescents and young adults with MMC, aged 16â30 years (25 males). Aerobic capacity was quantified by measuring peak oxygen uptake (peakVO2) during a maximal exercise test on a cycle or arm ergometer depending on the main mode of ambulation. Muscle strength of upper and lower extremity muscles was assessed using a hand-held dynamometer. Regarding flexibility, we assessed mobility of hip, knee and ankle joints. Body composition was assessed by measuring thickness of four skin-folds. Relations were studied using linear regression analyses. Average peakVO2 was 1.48 ± 0.52 l/min, 61% of the participants had subnormal muscle strength, 61% had mobility restrictions in at least one joint and average sum of four skin-folds was 74.8 ± 38.8 mm. PeakVO2 was significantly related to gender, ambulatory status and muscle strength, explaining 55% of its variance. Adolescents and young adults with MMC have poor health-related physical fitness. Gender and ambulatory status are important determinants of peakVO2. In addition, we found a small, but significant relationship between peakVO2 and muscle strength
Investigation of the nature of the unpaired electron states in the organic semiconductor N-methyl-N-ethylmorpholinium-tetracyanoquinodimethane
Rapid determination of anti-tuberculosis drug resistance from whole-genome sequences
Mycobacterium tuberculosis drug resistance (DR) challenges effective tuberculosis disease control. Current molecular tests examine limited numbers of mutations, and although whole genome sequencing approaches could fully characterise DR, data complexity has restricted their clinical application. A library (1,325 mutations) predictive of DR for 15 anti-tuberculosis drugs was compiled and validated for 11 of them using genomic-phenotypic data from 792 strains. A rapid online âTB-Profilerâ tool was developed to report DR and strain-type profiles directly from raw sequences. Using our DR mutation library, in silico diagnostic accuracy was superior to some commercial diagnostics and alternative databases. The library will facilitate sequence-based drug-susceptibility testing
leBIBIQBPP: a set of databases and a webtool for automatic phylogenetic analysis of prokaryotic sequences
Structure of K-Doped Polyacetylene and Its Variations with Annealing, Studied by Neutron Diffraction
NEURAL NETWORKS AS AN ALTERNATIVE METHOD FOR PREDICTING BACTERIAL GROWTH RATE FROM THE BEGINNING OF A GROWTH CURVE
International audienc
[Time-killing curves of Pseudomonas aeruginosa strains exposed to polymyxin B].
International audienceThe time-killing curves of three strains of Pseudomonas aeruginosa (PA01, ATCC10145 and ATCC27853) exposed to five concentrations of polymyxin B comprised: a latency phases, one or two decreasing phases and for the low polymyxin B concentrations a growth phasis. The five antibiotic concentrations were chosen to have a weak bactericidal effect such that decreasing exponential or biexponential models can be fitted to the data. In our experimental conditions, increasing Ca++ and Mg++ concentrations in the medium (Mueller-Hinton) reduced the bactericidal effect and increased the growth phases. Increasing inoculum (10(5) to 10(7) CFU/ml) decreased the bactericidal effect observed with polymyxin B
Accuracy of microbial growth predictions with square root and polynomial models
International audienc
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