13 research outputs found
Intravitreal bevacizumab (AvastinÂź) for diabetic retinopathy at 24-months: The 2008 Juan Verdaguer-planas lecture
Diabetic retinopathy (DR) remains the major threat to sight in the working age population. Diabetic macular edema (DME) is a manifestation of DR that produces loss of central vision. Proliferative diabetic retinopathy (PDR) is a major cause of visual loss in diabetic patients. In PDR, the growth of new vessels is thought to occur as a result of vascular endothelial growth factor (VEGF) release into the vitreous cavity as a response to ischemia. Furthermore, VEGF increases vessel permeability leading to deposition of proteins in the interstitium that facilitate the process of angiogenesis and macular edema. This review demonstrates multiple benefits of intravitreal bevacizumab (IVB) on DR including DME and PDR at 24 months of follow up. The results indicate that IVB injections may have a beneficial effect on macular thickness and visual acuity (VA) in diffuse diabetic macular edema. Therefore, in the future this new therapy could replace or complement focal/grid laser photocoagulation in DME. In PDR, this new option could be an adjuvant agent to pan-retina photocoagulation so that more selective therapy may be applied. In addition, we report a series of patients in which tractional retinal detachment developed or progressed after adjuvant preoperative IVB in severe PDR. © 2010 Bentham Science Publishers Ltd
On the process and outcomes of inquiry learning: Changing approaches to assessment
Inquiry learning is an educational approach that involves a process of exploration, asking questions and making discoveries in the search for new understandings. Researchers however are divided about the value of the approach. In the symposium, it is argued that one of the reasons for this controversy is the way that inquiry learning is assessed. Consequently, we aim to present papers which reflect on the challenge of assessing inquiry learning by describing the prevailing approaches to assessment and how technological and theoretical advancement is changing these approaches. The aim is not just to describe these approaches but reflect upon the opportunities that are created and difficulties that must be overcome as we pursue the goal of assessing the processes and outcomes of inquiry learnin
Formative assessment use in university EFL writing instruction: a survey report from China
Exploring the Utility of Sequential Analysis in Studying Informal Formative Assessment Practices
AnĂĄlise de jogos digitais em dispositivos mĂłveis para aprendizagem de lĂnguas estrangeiras
Improved switching transient model suitable for power loss evaluation of SiC-based asymmetric H-bridge power converters in SRGs
Intravitreal bevacizumab (AvastinÂź) for diabetic retinopathy at 24-months: The 2008 Juan Verdaguer-planas lecture
Diabetic retinopathy (DR) remains the major threat to sight in the working age population. Diabetic macular edema (DME) is a manifestation of DR that produces loss of central vision. Proliferative diabetic retinopathy (PDR) is a major cause of visual loss in diabetic patients. In PDR, the growth of new vessels is thought to occur as a result of vascular endothelial growth factor (VEGF) release into the vitreous cavity as a response to ischemia. Furthermore, VEGF increases vessel permeability leading to deposition of proteins in the interstitium that facilitate the process of angiogenesis and macular edema. This review demonstrates multiple benefits of intravitreal bevacizumab (IVB) on DR including DME and PDR at 24 months of follow up. The results indicate that IVB injections may have a beneficial effect on macular thickness and visual acuity (VA) in diffuse diabetic macular edema. Therefore, in the future this new therapy could replace or complement focal/grid laser photocoagulation in DME. In PDR, this new option could be an adjuvant agent to pan-retina photocoagulation so that more selective therapy may be applied. In addition, we report a series of patients in which tractional retinal detachment developed or progressed after adjuvant preoperative IVB in severe PDR. © 2010 Bentham Science Publishers Ltd