194 research outputs found

    Dynamical invariants for quantum control of four-level systems

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    We present a Lie-algebraic classification and detailed construction of the dynamical invariants, also known as Lewis-Riesenfeld invariants, of the four-level systems including two-qubit systems which are most relevant and sufficiently general for quantum control and computation. These invariants not only solve the time-dependent Schr\"odinger equation of four-level systems exactly but also enable the control, and hence quantum computation based on which, of four-level systems fast and beyond adiabatic regimes.Comment: 11 pages, 5 table

    Sequence analysis of the second internal Transcribed spacer (ITS2) region of rDNA for species identification of trichostrongylus nematodes isolated from domestic livestock in Iran

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    Background: Infectivity of herbivores with Trichostrongylus nematodes is widespread in many countries, having a major economic impact on breeding, survivability, and productivity of domestic livestock. This study was carried out on Trichostrongylus species isolated from domestic livestock in order to develop an easy-to-perform method for species identification. Methods: Trichostrongylus isolates were collected from sheep, goat, cattle, and buffaloes in Khuzestan Province, southwest Iran. Primary species identification was carried out based on morphological characterization of male worms. PCR amplification of ITS2-rDNA region was performed on genomic DNA and the products were sequenced. Phylogenetic analysis of the nucleotide sequence data was conducted employing Bayesian Inference approach. Consequently, a restriction fragment length polymorphism (RFLP) profile was designed to differentiate Trichostrongylus species. Results: A consensus sequence of 238 nucleotides was deposited in the GenBank for Iranian isolates of Trichostrongylus species including T. colubriformis, T. capricola, T. probolurus and T. vitrinus. The designated RFLP using restriction enzyme TasI could readily differentiate among species having different ITS2 sequence. The molecular analysis was in concordance with morphological findings. Conclusion: Phylogenetic analysis indicated a close relationship among the sequences obtained in this study and reference sequence of relevant species. ITS2-RFLP with TasI is recommended for molecular differentiation of common Trichostrongylus species

    Generalized Grassmannian Coherent States For Pseudo-Hermitian nn Level Systems

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    The purpose of this paper is to generalize fermionic coherent states for two-level systems described by pseudo-Hermitian Hamiltonian \cite{Trifonov}, to n-level systems. Central to this task is the expression of the coherent states in terms of generalized Grassmann variables. These kind of Grassmann coherent states satisfy bi-overcompleteness condition instead of over-completeness one, as it is reasonably expected because of the biorthonormality of the system. Choosing an appropriate Grassmann weight function resolution of identity is examined. Moreover Grassmannian coherent and squeezed states of deformed group SUq(2)SU_{q}(2) for three level pseudo-Hermitian system are presented.Comment: 17 page

    Genotyping Echinococcus granulosus from dogs from Western Iran

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    Cystic echinococcosis is a zoonotic infection caused by the dog tapeworm, Echinococcus granulosus. In the present study, adults of E. granulosus (n = 20) were collected from 71 dogs from Western Iran and were genetically characterized using DNA sequencing of the partial mitochondrial cytochrome c oxidase subunit 1 (cox1) and NADH dehydrogenase 1 (nad1). Consensus sequences were obtained for cox1 (366) and nad1 (471) genes. Phylogenetic analysis of concatenated nad1 and cox1 nucleotide sequence data was performed using Bayesian Inference approach. Overall, the dog isolates indicated nine different sequences in cox1 and seven in nad1 genes. Three genotypes (G1 [75%], G2 [10%] and G3 [15%]) were identified from the isolates. The G2 sequences indicated 100% homology with reference G2 sequence in both cox1 (Genbank accession number M84662) and nad1 (AJ237633) genes. G3 sequences showed 100% homology with G3 reference sequence in nad1 (AJ237633), but displayed two different cox1 profiles, each having 99% homology with reference G3 sequence (M84663). In the phylogenetic tree all of the isolates were grouped into a distinct cluster corresponding to the G1-G3 complex with relevant reference sequences. The presence of G1 genotype (sheep strain) of E. granulosus sensu stricto as dominant genotype in dogs is emphasized. To the best of our knowledge, this study established the first record of E. granulosus sensu stricto, G2 genotype in Iran. © 2012 Elsevier Inc

    Expandable DNA repeat and human hereditary disorders

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    Background & Aims: Nearly 30 hereditary disorders in humans result from an increase in the number of copies of simple repeats in genomic DNA, including fragile X syndrome, myotonic dystrophy, Huntington’s disease, and Friedreich’s ataxia. One the most frequently occurring types of mutation is trinucleotide repeat expansion. The present study was conducted with the aim of investigating the cause and molecular mechanisms of repeat expansions DNA and their pathogenic mechanisms in diverse classes of genetic diseases. Methods: Scientific databases were searched using the keywords expandable DNA repeat fragile X, myotonic dystrophy, Huntington’s disease, and Friedreich’s ataxia. After primary screening, articles which were related to the studies topic were further considered and analyzed. Results: DNA repeats seem to be predisposed to such expansion due to their unusual structural features, which disrupt the cellular replication, repair, and recombination processes. The majority of these debilitating diseases are caused by repeat expansions in the noncoding regions of their resident genes. The pathogenic mechanism underling these disorders include loss of function in protein and gain of function in protein or ribonucleic acid (RNA). Conclusion: Although diseases caused by trinucleotide repeat expansion vary in their phenotypes, they are somewhat similar in their pathogenic mechanism and medical findings. It is likely that progress made in this field will be beneficial to patients who have other neurological diseases. © 2016, Kerman University of Medical Sciences. All rights reserved

    Ganoderma lucidum: A promising anti-inflammatory medicinal plant

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    Inflammation is a complex process and part of the host immune defense against invading micro-organism or trauma. Over production of some pro-inflammatory mediators can lead to chronic diseases of the inflammatory origin. Medicinal Plants which are used as anti-inflammatory agents, mainly act affecting various stages of the process of inflammation. In general they can inhibit formation of a wide of mediators such as cytokines by immune cells to prevent the inflammatory reaction cascade from starting. The use of most of the medicinal plants in treatment of chronic disease of the inflammatory origin is based on clinical and pharmacological trials. Meanwhile, the use of most of them is based on their longstanding traditional use in folk medicine. In this review, we report some of anti-inflammatory effects of G. lucidum as an ancient Chinese herbal medicine

    Genotyping Echinococcus granulosus from dogs from Western Iran

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    Cystic echinococcosis is a zoonotic infection caused by the dog tapeworm, Echinococcus granulosus. In the present study, adults of E. granulosus (n = 20) were collected from 71 dogs from Western Iran and were genetically characterized using DNA sequencing of the partial mitochondrial cytochrome c oxidase subunit 1 (cox1) and NADH dehydrogenase 1 (nad1). Consensus sequences were obtained for cox1 (366) and nad1 (471) genes. Phylogenetic analysis of concatenated nad1 and cox1 nucleotide sequence data was performed using Bayesian Inference approach. Overall, the dog isolates indicated nine different sequences in cox1 and seven in nad1 genes. Three genotypes (G1 [75%], G2 [10%] and G3 [15%]) were identified from the isolates. The G2 sequences indicated 100% homology with reference G2 sequence in both cox1 (Genbank accession number M84662) and nad1 (AJ237633) genes. G3 sequences showed 100% homology with G3 reference sequence in nad1 (AJ237633), but displayed two different cox1 profiles, each having 99% homology with reference G3 sequence (M84663). In the phylogenetic tree all of the isolates were grouped into a distinct cluster corresponding to the G1-G3 complex with relevant reference sequences. The presence of G1 genotype (sheep strain) of E. granulosus sensu stricto as dominant genotype in dogs is emphasized. To the best of our knowledge, this study established the first record of E. granulosus sensu stricto, G2 genotype in Iran. © 2012 Elsevier Inc

    The immunopathobiology of T cells in stress condition: a review

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    Several factors impact the immune responses such as the chemical nature of antigens, the physiologic and metabolic condition of the responsive cells, the site of antigen recognition, and neuroendocrine and pharmacological received agents. Incompatibility of host immune responses to the entrapped antigens leads to an immune pathological manner instead of an immune protection which results in the disharmony of the immune effective factors. Besides the fact that stress is one of the most common effective factors in human life, it also contributed to the protection, suppression, and pathology of the immune system. In this review article, the direct and indirect effects of the stress on the function of T cells and the contributed mechanism of action will be discussed. © 2020, Cell Stress Society International

    Genetic characterization of Echinococcus granulosus from a large number of formalin-fixed, paraffin-embedded tissue samples of human isolates in Iran

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    Cystic echinococcosis (CE), caused by the larval stage of Echinococcus granulosus, presents an important medical and veterinary problem globally, including that in Iran. Different genotypes of E. granulosus have been reported from human isolates worldwide. This study identifies the genotype of the parasite responsible for human hydatidosis in three provinces of Iran using formalin-fixed paraffin-embedded tissue samples. In this study, 200 formalin-fixed paraffin-embedded tissue samples from human CE cases were collected from Alborz, Tehran, and Kerman provinces. Polymerase chain reaction amplification and sequencing of the partial mitochondrial cytochrome c oxidase subunit 1 gene were performed for genetic characterization of the samples. Phylogenetic analysis of the isolates from this study and reference sequences of different genotypes was done using a maximum likelihood method. In total, 54.4%, 0.8%, 1%, and 40.8% of the samples were identified as the G1, G2, G3, and G6 genotypes, respectively. The findings of the current study confirm the G1 genotype (sheep strain) to be the most prevalent genotype involved in human CE cases in Iran and indicates the high prevalence of the G6 genotype with a high infectivity for humans. Furthermore, this study illustrates the first documented human CE case in Iran infected with the G2 genotype. Copyright © 2015 by The American Society of Tropical Medicine and Hygiene
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