237 research outputs found

    Transient development of gravity waves for two layered fluids

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    The transient gravity waves generated by a harmonically oscillating wave maker immersed in two incompressible fluids, the upper fluid having a free surface, is considered. The resulting linearized initial value problem is solved using the method of generalized functions, and asymptotic analysis for large time and distance are given for the elevation

    Possible protective and curative effects of selenium nanoparticles on testosterone-induced benign prostatic hyperplasia rat model

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    Background: Men over the age of 40 are more likely to develop benign prostatic hyperplasia (BPH). BPH is characterized by proliferation of the prostatic epithelium and stroma. Selenium nanoparticles (SeNPs), is an essential metalloid mineral and antioxidant. In this study, SeNPs were tested for their potential protective and curative impacts on BPH in rats. Materials and methods: 50 male Sprague-Dawley rats were randomly divided into five groups: Group I (Control group); Group II (Orchiectomized group): bilateral orchiectomy was conducted on rats; Group III (BPH group): testosterone (TE) enanthate injection was used to induce BPH; Group IV (Protective group): rats were given SeNP before subjecting rats to BPH; Group V (Curative group): rats were succumbed to BPH, followed by administration of SeNP. Measurement of prostate specific antigen (PSA) and TE in serum was performed and prostates were weighed and prepared for histological, immunohistochemical and ultrastructural examination. Results: In the BPH group, serum TE- and PSA-levels, as well as prostate weight, increased significantly and significant decreases in the protective and curative groups. Reduced acinar lumen, expansion of stroma and epithelial hyperplasia were noticed in the BPH group, which were ameliorated significantly both in protective and curative groups. There was an increase in PCNA immunoreaction in the BPH group and a decrease in both the protective and curative groups. On TEM of BPH group, the nuclei appeared irregular with dilated endoplasmic reticulum, loss of cell boundaries and apical microvilli. The protective group showed more improvement than the curative group. Conclusions: The effects of SeNPs on BPH induced by TE in rats, were both protective and curative, although the protective effects were more pronounced

    ЕFFЕCT OF SOMЕ ЕSSЕNTIAL OILS ON GRЕY MOULD, CAUSЕD BY Botrytis cinеrеa ON TABLЕ GRAPЕ AT COLD-STORAGЕ

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    Еssеntial oils (ЕOs) from cinnamon (Cinnamon zylanicum), clovе (Syzygium aromaticum) camphor (Еucalyptus globulus), and rockеt (Еruca sativa), wеrе еvaluatеd for thеir botryocidal еffеct. In-vitro, Botrytis cinеrеa was еxposеd to 4 diffеrеnt concеntrations of ЕOs, using thrее diffеrеnt tеchniquеs, i.е. amеndеd mеdium, vapourisation, and volatilising.  Cinnamon and clovе ЕOs wеrе thе highеst tеstеd concеntrations found to bе thе most еffеctivе in all tеchniquеs which complеtеly inhibitеd 100% of radial growth for B. cinеrеa in vitro. A post-harvеst trial to control grеy mould on grapе bunchеs of Flamе sееdlеss and Supеrior sееdlеss cvs. were conductеd using cinnamon and clovе oils in sеasons 2014 and 2015. Both of the two ЕOs wеrе usеd at concеntrations of 25, 50 and 100 µL./L-1air v/v, еxposеd as vapour trеatmеnt significantly supprеssеd grеy mould during thе cold-storagе. Thеrе was not a significancе diffеrеncеs obsеrvеd among both ЕOs trеatmеnts. Howеvеr, cinnamon at 100 µL.1L-1air v/v was thе most еffеctivе trеatmеnt to control grеy mould of both grapе cultivar

    Sunset Yellow and Allura Red modulate Bcl2 and COX2 expression levels and confer oxidative stress-mediated renal and hepatic toxicity in male rats

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    Studies on the adverse health effects caused by azo dyes are insufficient and quite contradictory. This work aims to investigate the possible toxic effect of two types of widely used food additives, Sunset Yellow and Allura Red, by assessing the physiological, histopathological and ultrastructural changes in the liver and kidney. Also, we investigated the genotoxic effect of both dyes on white blood cells. Thirty adult male albino rats were divided into three groups of 10 animals each: control (received water), Sunset Yellow-treated (2.5 mg/kg body weight) and Allura Red-treated (seven mg/kg body weight). The doses were orally applied for 4 weeks. Our results indicated an increase in the biochemical markers of hepatic and renal function (Aspartate aminotransferase, alanine aminotransferase, urea, uric acid and creatinine) in animals administered with the azo dyes. We also observed a noticeable increase in MDA and a marked decrease in total antioxidant levels in azo dye-treated animals compared to controls. Conversely, both dyes adversely affected the liver and kidney of albino rats and altered their histological and fine structure, with downregulation of Bcl2 and upregulation of COX2 expression. Our comet assay results showed a significant elevation in the fold change of tail moment in response to application of Sunset Yellow but not Allura Red. Collectively, we show that Sunset Yellow and Allura Red cause histopathological and physiological aberrations in the liver and kidney of male Wistar albino rats. Moreover, Sunset Yellow but not Allura Red induces a potential genotoxic effect

    IMPACT OF FLAXSEED INCLUSION IN DAMASCUS GOAT'S RATION ON DIGESTIBILITY, SOME BLOOD PARAMETERS AND REPRODUCTIVE PERFORMANCE

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    Feeding flaxseed to dairy animals improve milk production and reproductive performance. So, the objective of our study was to investigate effect of inclusion flaxseed in Damascus goat's ration on its reproductive performance. Twenty-four Damascus goats (31.40 ±0.50 kg weight and 2-3 years old) were divided into three groups (randomly, eight animals each). The basic diet of  control group (T1) consisted of 56.67% concentrate feed mixture (CFM) and 33.33% Alfalfa hay, while the groups T2 and T3 supplemented with 10% full fat soya, 5% flaxseed + 5% full fat soya and 10% flaxseed, respectively. Inclusion flaxseed in goat’s ration at rate of 5 and 10% resulted in significant increase in all nutrients digestibility, except nitrogen free extract digestibility (NFE) as well as the nutritive values as total digestible nutrients (TDN). Dry matter intakes (DMI) of the different experimental groups were comparable. Goats in T3 recorded the highest does conceived, twinning, conception and kidding rates % as well as total kids born, than other groups (T1 and T2). On the hand T3 recorded the lowest aborted does and barren does (Zero) compared to T1 and T2. Animals of T3 recorded significant higher of total protein, globulin, Albumin and urea concentration than T1 and T2. Concerning lipids profile, the animals of T3 recorded significant lower triglycerides, cholesterol and Low-density lipoprotein concentration than those of T1 and T2. While the animals of T3 recorded significant higher High-density lipoprotein concentration compared to  T2 and T1. The body weight of does is not significantly affected by any of three treatments. In conclusion, flaxseed supplementations in Damascus goat's diets during the gestation period lead to improve total tract digestibility, reduced blood lipids and normalize renal and hepatic functions and improved its reproductive performance, especially those fed on diets containing 10% flaxseed

    Server‐side workflow execution using data grid technology for reproducible analyses of data‐intensive hydrologic systems

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    Many geoscience disciplines utilize complex computational models for advancing understanding and sustainable management of Earth systems. Executing such models and their associated data preprocessing and postprocessing routines can be challenging for a number of reasons including (1) accessing and preprocessing the large volume and variety of data required by the model, (2) postprocessing large data collections generated by the model, and (3) orchestrating data processing tools, each with unique software dependencies, into workflows that can be easily reproduced and reused. To address these challenges, the work reported in this paper leverages the Workflow Structured Object functionality of the Integrated Rule‐Oriented Data System and demonstrates how it can be used to access distributed data, encapsulate hydrologic data processing as workflows, and federate with other community‐driven cyberinfrastructure systems. The approach is demonstrated for a study investigating the impact of drought on populations in the Carolinas region of the United States. The analysis leverages computational modeling along with data from the Terra Populus project and data management and publication services provided by the Sustainable Environment‐Actionable Data project. The work is part of a larger effort under the DataNet Federation Consortium project that aims to demonstrate data and computational interoperability across cyberinfrastructure developed independently by scientific communities.Plain Language SummaryExecuting computational workflows in the geosciences can be challenging, especially when dealing with large, distributed, and heterogeneous data sets and computational tools. We present a methodology for addressing this challenge using the Integrated Rule‐Oriented Data System (iRODS) Workflow Structured Object (WSO). We demonstrate the approach through an end‐to‐end application of data access, processing, and publication of digital assets for a scientific study analyzing drought in the Carolinas region of the United States.Key PointsReproducibility of data‐intensive analyses remains a significant challengeData grids are useful for reproducibility of workflows requiring large, distributed data setsData and computations should be co‐located on servers to create executable Web‐resourcesPeer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/137520/1/ess271_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/137520/2/ess271.pd
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