Urban heat stress vulnerability in the U.S. Southwest: The role of sociotechnical systems

Heat vulnerability of urban populations is becoming a major issue of concern with climate change, particularly in the cities of the Southwest United States. In this article we discuss the importance of understanding coupled social and technical systems, how they constitute one another, and how they form the conditions and circumstances in which people experience heat. We discuss the particular situation of Los Angeles and Maricopa Counties, their urban form and the electric grid. We show how vulnerable populations are created by virtue of the age and construction of buildings, the morphology of roads and distribution of buildings on the landscape. Further, the regulatory infrastructure of electricity generation and distribution also contributes to creating differential vulnerability. We contribute to a better understanding of the importance of sociotechnical systems. Social infrastructure includes codes, conventions, rules and regulations; technical systems are the hard systems of pipes, wires, buildings, roads, and power plants. These interact to create lock-in that is an obstacle to addressing issues such as urban heat stress in a novel and equitable manner

Rain driven by receding ice sheets as a cause of past climate change

The Younger Dryas cold period, which interrupted the transition from the last ice age to modern conditions in Greenland, is one of the most dramatic incidents of abrupt climate change reconstructed from paleoclimate proxy records. Changes in the Atlantic Ocean overturning circulation in response to freshwater fluxes from melting ice are frequently invoked to explain this and other past climate changes. Here we propose an alternative mechanism in which the receding glacial ice sheets cause the atmospheric circulation to enter a regime with greater net precipitation in the North Atlantic region. This leads to a significant reduction in ocean overturning circulation, causing an increase in sea ice extent and hence colder temperatures. Positive feedbacks associated with sea ice amplify the cooling. We support the proposed mechanism with the results of a state-of-the-art global climate model. Our results suggest that the atmospheric precipitation response to receding glacial ice sheets could have contributed to the Younger Dryas cooling, as well as to other past climate changes involving the ocean overturning circulation

Synaptic NMDA receptors mediate hypoxic excitotoxic death

Excessive NMDA receptor activation and excitotoxicity underlies pathology in many neuropsychiatric and neurological disorders, including hypoxia/ischemia. Thus, the development of effective therapeutics for these disorders demands a complete understanding of NMDA receptor (NMDAR) activation during excitotoxic insults. The extrasynaptic NMDAR hypothesis posits that synaptic NMDARs are neurotrophic/neuroprotective and extrasynaptic NMDARs are neurotoxic. The extrasynaptic hypothesis is built in part on observed selectivity for extrasynaptic receptors of a neuroprotective use-dependent NMDAR channel blocker, memantine. In rat hippocampal neurons, we found that a neuroprotective concentration of memantine shows little selectivity for extrasynaptic NMDARs when all receptors are tonically activated by exogenous glutamate. This led us to test the extrasynaptic NMDAR hypothesis using metabolic challenge, where the source of excitotoxic glutamate buildup may be largely synaptic. Three independent approaches suggest strongly that synaptic receptors participate prominently in hypoxic excitotoxicity. First, block of glutamate transporters with a nonsubstrate antagonist exacerbated rather than prevented damage, consistent with a primarily synaptic source of glutamate. Second, selective, preblock of synaptic NMDARs with a slowly reversible, use-dependent antagonist protected nearly fully against prolonged hypoxic insult. Third, glutamate pyruvate transaminase, which degrades ambient but not synaptic glutamate, did not protect against hypoxia but protected against exogenous glutamate damage. Together, these results suggest that synaptic NMDARs can mediate excitotoxicity, particularly when the glutamate source is synaptic and when synaptic receptor contributions are rigorously defined. Moreover, the results suggest that in some situations therapeutically targeting extrasynaptic receptors may be inappropriate

Synaptic NMDA receptors mediate hypoxic excitotoxic death

Excessive NMDA receptor activation and excitotoxicity underlies pathology in many neuropsychiatric and neurological disorders, including hypoxia/ischemia. Thus, the development of effective therapeutics for these disorders demands a complete understanding of NMDA receptor (NMDAR) activation during excitotoxic insults. The extrasynaptic NMDAR hypothesis posits that synaptic NMDARs are neurotrophic/neuroprotective and extrasynaptic NMDARs are neurotoxic. The extrasynaptic hypothesis is built in part on observed selectivity for extrasynaptic receptors of a neuroprotective use-dependent NMDAR channel blocker, memantine. In rat hippocampal neurons, we found that a neuroprotective concentration of memantine shows little selectivity for extrasynaptic NMDARs when all receptors are tonically activated by exogenous glutamate. This led us to test the extrasynaptic NMDAR hypothesis using metabolic challenge, where the source of excitotoxic glutamate buildup may be largely synaptic. Three independent approaches suggest strongly that synaptic receptors participate prominently in hypoxic excitotoxicity. First, block of glutamate transporters with a nonsubstrate antagonist exacerbated rather than prevented damage, consistent with a primarily synaptic source of glutamate. Second, selective, preblock of synaptic NMDARs with a slowly reversible, use-dependent antagonist protected nearly fully against prolonged hypoxic insult. Third, glutamate pyruvate transaminase, which degrades ambient but not synaptic glutamate, did not protect against hypoxia but protected against exogenous glutamate damage. Together, these results suggest that synaptic NMDARs can mediate excitotoxicity, particularly when the glutamate source is synaptic and when synaptic receptor contributions are rigorously defined. Moreover, the results suggest that in some situations therapeutically targeting extrasynaptic receptors may be inappropriate

The reversibility of sea ice loss in a state-of-the-art climate model

Rapid Arctic sea ice retreat has fueled speculation about the possibility of threshold (or ‘tipping point’) behavior and irreversible loss of the sea ice cover. We test sea ice reversibility within a state-of-the-art atmosphere–ocean global climate model by increasing atmospheric carbon dioxide until the Arctic Ocean becomes ice-free throughout the year and subsequently decreasing it until the initial ice cover returns. Evidence for irreversibility in the form of hysteresis outside the envelope of natural variability is explored for the loss of summer and winter ice in both hemispheres. We find no evidence of irreversibility or multiple ice-cover states over the full range of simulated sea ice conditions between the modern climate and that with an annually ice-free Arctic Ocean. Summer sea ice area recovers as hemispheric temperature cools along a trajectory that is indistinguishable from the trajectory of summer sea ice loss, while the recovery of winter ice area appears to be slowed due to the long response times of the ocean near the modern winter ice edge. The results are discussed in the context of previous studies that assess the plausibility of sea ice tipping points by other methods. The findings serve as evidence against the existence of threshold behavior in the summer or winter ice cover in either hemisphere

Hadley Circulation Response to Orbital Precession. Part I: Aquaplanets

The response of the monsoonal and annual-mean Hadley circulation to orbital precession is examined in an idealized atmospheric general circulation model with an aquaplanet slab-ocean lower boundary. Contrary to expectations, the simulated monsoonal Hadley circulation is weaker when perihelion occurs at the summer solstice than when aphelion occurs at the summer solstice. The angular momentum balance and energy balance are examined to understand the mechanisms that produce this result. That the summer with stronger insolation has a weaker circulation is the result of an increase in the atmosphere’s energetic stratification, the gross moist stability, which increases more than the amount required to balance the change in atmospheric energy flux divergence necessitated by the change in top-of-atmosphere net radiation. The solstice-season changes result in annual-mean Hadley circulation changes (e.g., changes in circulation strength)

The Tropical Precipitation Response to Orbital Precession

Orbital precession changes the seasonal distribution of insolation at a given latitude but not the annual mean. Hence, the correlation of paleoclimate proxies of annual-mean precipitation with orbital precession implies a nonlinear rectification in the precipitation response to seasonal solar forcing. It has previously been suggested that the relevant nonlinearity is that of the Clausius–Clapeyron relationship. Here it is argued that a different nonlinearity related to moisture advection by the atmospheric circulation is more important. When perihelion changes from one hemisphere’s summer solstice to the other’s in an idealized aquaplanet atmospheric general circulation model, annual-mean precipitation increases in the hemisphere with the brighter, warmer summer and decreases in the other hemisphere, in qualitative agreement with paleoclimate proxies that indicate such hemispherically antisymmetric climate variations. The rectification mechanism that gives rise to the precipitation changes is identified by decomposing the perturbation water vapor budget into “thermodynamic” and “dynamic” components. Thermodynamic changes (caused by changes in humidity with unchanged winds) dominate the hemispherically antisymmetric annual-mean precipitation response to precession in the absence of land–sea contrasts. The nonlinearity that enables the thermodynamic changes to affect annual-mean precipitation is a nonlinearity of moisture advection that arises because precession-induced seasonal humidity changes correlate with the seasonal cycle in low-level convergence. This interpretation is confirmed using simulations in which the Clausius–Clapeyron relationship is explicitly linearized. The thermodynamic mechanism also operates in simulations with an idealized representation of land, although in these simulations the dynamic component of the precipitation changes is also important, adding to the thermodynamic precipitation changes in some latitudes and offsetting it in others

Hadley Circulation Response to Orbital Precession. Part II: Subtropical Continent

The response of the monsoonal and annual-mean Hadley circulation to orbital precession is examined in an idealized atmospheric general circulation model with a simplified representation of land surface processes in subtropical latitudes. When perihelion occurs in the summer of a hemisphere with a subtropical continent, changes in the top-of-atmosphere energy balance, together with a poleward shift of the monsoonal circulation boundary, lead to a strengthening of the monsoonal circulation. Spatial variations in surface heat capacity determine whether radiative perturbations are balanced by energy storage or by atmospheric energy fluxes. Although orbital precession does not affect annual-mean insolation, the annual-mean Hadley circulation does respond to orbital precession because its sensitivity to radiative changes varies over the course of the year: the monsoonal circulation in summer is near the angular momentum-conserving limit and responds directly to radiative changes; whereas in winter, the circulation is affected by the momentum fluxes of extratropical eddies and is less sensitive to radiative changes