The Sickle Cell Trait and Sickle Cell Anaemia With Special Reference to an Investigation in the Gold Coast

Abstract Not Provided

Mobile Phone Service Process Hiccups at Cellular, Inc.

This teaching case documents an actual case of process execution and failure. The case is useful in MIS introductory courses seeking to demonstrate the interdependencies within a business process, and the concept of cascading failure at the process level. This case demonstrates benefits and potential problems with information technology systems, how business processes transcend departments, and how cascading failure may arise. It has been used successfully in undergraduate MIS core business courses and is appropriate for graduate MIS as well as IS design courses. When a customer tries to purchase a cell phone and a service contract from Cellular Inc. using their ecommerce site, an expired advertisement begins a cascade of problems that occur throughout the customer-visible portions of the procurement/fulfillment process. The president of the company introduces the case as a catalyst for process improvement. He tasks his cross-functional business team to design an improved business process that will prevent the identified problems from occurring again. Students are tasked with defining the detailed steps occurring in the actual process and to define an improved process. Opportunities with design and theoretical contributions to improving the process are discussed

Descriptions of the pupae and larvae of Stenopsyche siamensis Martynov, 1931 (Trichoptera: Stenopsychidae) with notes on larval biology

Detailed descriptions are given of the pupae and larvae of Stenopsyche siamensis Martynov, and comparisons are made with the immature stages of other Stenopsyche species previously described from Asia. The larval feeding biology of S. siamensis and its position in stream communities are briefly discussed

Final Cultural Resources Report For The Salt Creek Midstream, LLC Proposed Waha II Pipeline Project On State Of Texas Lands In Reeves County, Texas

Enercon Services, Inc. (ENERCON), in support of Salt Creek Midstream, LLC, conducted an intensive archeological survey for the proposed Waha II Pipeline Project. The proposed pipeline is approximately 27.33 miles in length, located near Pecos, Texas in Reeves County. This report encompasses only the two State of Texas Lands, administered by the Texas General Land Office (TGLO), segments of the proposed Waha II Pipeline Project which is approximately 0.69-miles (3,666 feet) in length in Reeves County. The State of Texas Lands portion of the project area is mapped on the United States Geological Survey (USGS) Toyah Lake, Tex. (1963), and Old X Ranch, Tex. (1963, Photorevised 1981), 7.5 Minute Quadrangles. The construction corridor consists of a 50-foot-wide permanent pipeline right-of-way (ROW) and a 50-footwide temporary workspace corridor. The cultural resources survey corridor was 100 feet wide for the entire 0.69-mile length of the pipeline segment through the State of Texas Lands. The total area inspected during the cultural resources survey of the State of Texas Lands was 8.43 acres (3.41 hectares). The survey of the State of Texas property was completed under Texas Antiquities Permit No. 9017. The cultural resources field investigation on State of Texas Lands occurred on August 2 and 3, 2018 by J. Matthew Oliver and Gary D. Edington and consisted of an intensive pedestrian survey utilizing transects not spaced greater than 15 meters apart with shovel tests. The field investigation was conducted in accordance with the Texas Historical Commission (THC) Archeological Survey Standards for Texas. The entire project was supervised by Gary D. Edington, an ENERCON archeologist who meets the U.S. Secretary of the Interior’s Professional Qualification Standards for archeology as set forth in 36 CFR 61. The cultural resources survey resulted in the observation of two isolated finds (IF). IF#8 is a single lithic flake of brown chert observed on the surface in the east tract of State of Texas Lands. IF#9 is a small bulldozer push-pile of old wooden fence posts and barbed wire observed adjacent to the east fence line of the east tract of Texas State lands. IF#8 and IF#9 lack information potential and are not eligible for the National Register of Historic Places (NRHP) or State Antiquities Landmarks (SAL). The cultural resources survey did not result in finding any additional historic or prehistoric artifacts, features, cultural lenses, or sites over 50 years of age on State of Texas Lands. No archeological sites were encountered, and no artifacts were collected. Therefore, it is recommended that the project will have no effect on any cultural resources that may qualify for inclusion to the NRHP on State of Texas Lands. No further cultural resources investigations are recommended prior to construction of the proposed Waha II Pipeline project on State of Texas Lands. If cultural material, including sites, features, or artifacts that are 50 years old or older are encountered within the ROW during construction of this project, work in the area must cease and the regional THC Archeologist must be immediately be notified

Cultural Resources Report For The Salt Creek Midstream, LLC Proposed Halcon Pipeline On Texas General Land Office Lands In Reeves County, Texas

Enercon Services, Inc. (ENERCON), in support of Salt Creek Midstream, LLC, conducted an intensive cultural resources survey for the proposed Halcon Pipeline. The proposed pipeline is approximately 43.3 miles (69.7 km) in length and located near Pecos, Texas in Ward and Reeves counties. This report encompasses only the portion of the proposed Halcon Pipeline located on two tracts of Permanent School Fund land in Reeves County, Texas. The Permanent School Fund is administered by the Texas General Land Office (TGLO), a political subdivision of the State of Texas. The portion of the Halcon Pipeline on TGLO lands is approximately 1.8 miles (2.8 km) in length and depicted on the United States Geological Survey (USGS) Quito Draw, Tex. (1963, Photorevised 1981), Old X Ranch, Tex. (1963, Photorevised 1981), Toyah Lake, Tex. (1963) 7.5 Minute Quadrangle maps. The construction corridor consists of a 50 feet (15 m) wide permanent pipeline right-of-way (ROW) and an additional 50 feet (15 m) wide temporary workspace corridor. The cultural resources survey area of potential effect (APE) consists of the 1.8 mile (2.8 km) by 100 feet (30 m) corridor, totaling 21.3 acres (8.6 hectares). The cultural resources investigation is intended to assist in adhering to the 1969 Antiquities Code of Texas and the cultural resources survey on TGLO lands was completed under Texas Antiquities Permit No. 8275. The entire project was supervised by Michael M. Margolis, an ENERCON archeologist who meets the U.S. Secretary of the Interior’s Professional Qualification Standards for archeology as set forth in 36 CFR 61. Prior to the survey, a search of the Texas Archeological Sites Atlas (the Atlas) was conducted by Michael M. Margolis to locate previously recorded archeological sites, archeological surveys, National Register of Historic Places (NRHP) properties, and State Antiquities Landmarks (SALs). Based on the Atlas, one site, 41RV60, has been previously recorded within 1-mile of the APE on TGLO lands. Site 41RV60 is an Early Archaic lithic scatter recorded by URS Corporation in March 2014 and was determined ineligible for listing on the NRHP by the State Historic Preservation Officer (SHPO) on April 8, 2014. Site 41RV60 is located approximately 4,500 feet (1,372 m) from the APE and will not be impacted by construction of the proposed Halcon Pipeline. Two archeological surveys or studies are mapped within 1-mile of the APE on TGLO lands. The cultural resources survey of the Halcon Pipeline APE on TGLO lands was conducted December 1-2, 2017 by Julie Wasinger and Gary D. Edington, ENERCON archeologists who meet the U.S. Secretary of the Interior’s Professional Qualification Standards for archeology as set forth in 36 CFR 61. Salt Creek Midstream, LLC procedures dictate that all standing structures be avoided during construction. Fieldwork was conducted in accordance with the Texas Historical Commission (THC) Archeological Survey Standards for Texas. The cultural resources survey of the Halcon Pipeline APE did not result in finding any historic or prehistoric artifacts, features, cultural lenses, or sites and no artifacts were collected on TGLO lands. Therefore, it is recommended that construction of the proposed Halcon Pipeline on TGLO lands will have no effect on any historic property that may qualify for inclusion on the NRHP or SAL listings. No further cultural resources investigations are recommended prior to construction of the proposed Halcon Pipeline on TGLO lands. If cultural material, including sites, features, or artifacts that are 50 years old or older are encountered within the APE during construction of the Halcon Pipeline on TGLO lands, work in the area must cease and the regional THC Archeologist (512-463-6096) must be notified immediately

RNA Interference Demonstrates a Role for nautilus in the Myogenic Conversion of Schneider Cells by daughterless

AbstractSchneider SL2 cells activate the myogenic program in response to the ectopic expression of daughterless alone, as indicated by exit from the cell cycle, syncytia formation, and the presence of muscle myosin fibrils. Myogenic conversion can be potentiated by the coexpression of DMEF2 and nautilus with daughterless. In RT-PCR assays Schneider cells express two mesodermal markers, nautilus and DMEF2 mRNAs, as well as very low levels of daughterless mRNA but no twist. Full-length RT-PCR products for nautilus and DMEF2 encode immunoprecipitable proteins. We used RNA-i to demonstrate that both endogenous nautilus expression and DMEF2 expression are required for the myogenic conversion of Schneider cells by daughterless. Coexpression of twist blocks conversion by daughterless but twist dsRNA has no effect. Our results indicate that Schneider cells are of mesodermal origin and that myogenic conversion with ectopic expression of daughterless occurs by raising the levels of daughterless protein sufficiently to allow the formation of nautilus/daughterless heterodimers. The effectiveness of RNA-i is dependent upon protein half-life. Genes encoding proteins with relatively short half-lives (10 h), such as nautilus or HSF, are efficiently silenced, whereas more stable proteins, such as cytoplasmic actin or β-galactosidase, are less amenable to the application of RNA-i. These results support the conclusion that nautilus is a myogenic factor in Drosophila tissue culture cells with a functional role similar to that of vertebrate MyoD. This is discussed with regard to the in vivo functions of nautilus