12 research outputs found
Arrays of Nano-Electromechanical Biosensors Functionalized by Microcontact Printing
The biofunctionalization of nanoelectromechanical structures is critical for
the development of new classes of biosensors displaying improved performances
and higher-level of integration. We propose a modified microcontact printing
method for the functionalization and passivation of large arrays of
nanocantilevers in a single, self-aligned step. Using fluorescence microscopy
and resonant frequency measurements, we demonstrate (1) the bioactivity and the
anti-fouling property of deposited antibodies and BSA molecules and (2) the
preservation of the nanostructures' mechanical integrity.Comment: 20 pages, 5 figure
Crossbar arrays based on "Wall" Phase-Change Memory (PCM) and Ovonic-Threshold Switching (OTS) selector: a device integration challenge towards new computing paradigms in embedded applications
International audienceIn this work, we demonstrate the integration feasibility of Crossbar arrays based on Ovonic-Threshold Switching (OTS) selector and "Wall"-based Phase-Change Memory, realized with a "Double-Patterned Self-Aligned" (DPSA) structure in the Back-End-of-Line (BEOL) of the CMOS fabrication. We fabricated devices with critical dimensions down to 60 nmĂ—80 nm, integrating materials providing improved thermal stability (against BEOL thermal budget). Preliminary statistical electrical tests performed in 1 kb 1T1S1R arrays confirm the devices correct programming and cycling operations. These results pave the way to the integration of Crossbar arrays in embedded applications
Crossbar Arrays based on “Wall” Phase-Change Memory (PCM) and Ovonic- Threshold Switching (OTS) Selector: a Device Integration Challenge Towards New Computing Paradigms in Embedded Applications
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Atmospheric pressure non-thermal plasma exposure reduces Pseudomonas aeruginosa lipopolysaccharide toxicity in vitro and in vivo
Numerical modelling of the effects of cold atmospheric plasma on mitochondrial redox homeostasis and energy metabolism
Cold atmospheric helium plasma causes synergistic enhancement in cell death with hyperthermia and an additive enhancement with radiation
The Production of Plasma Activated Water in Controlled Ambient Gases and its Impact on Cancer Cell Viability
Antibacterial efficacy of cold atmospheric plasma against Enterococcus faecalis planktonic cultures and biofilms in vitro
Oxidative modification and electrochemical inactivation of Escherichia coli upon cold atmospheric pressure plasma exposure
Skin Changes During Ageing
International audienceThe skin provides the primary protection for the body against external injuries and is essential in the maintenance of general homeostasis. During ageing, resident cells become senescent and the extracellular matrix, mainly in the dermis, is progressively damaged affecting the normal organization of the skin and its capacity for repair. In parallel, extrinsic factors such as ultraviolet irradiation, pollution, and intrinsic factors such as diabetes or vascular disease can further accelerate this phenomenon. Indeed, numerous mechanisms are involved in age-induced degradation of the skin and these also relate to non-healing or chronic wounds in the elderly. In particular, the generation of reactive oxygen species seems to play a major role in age-related skin modifications. Certainly, targeting both the hormonal status of the skin or its surface nutrition can slow down age-induced degradation of the skin and improve healing of skin damage in the elderly. Skin care regimens that prevent radiation and pollution damage, and reinforce the skin surface and its microbiota are among the different approaches able to minimize the effects of ageing on the skin