1,719 research outputs found

    Fault diagnosis of operational synchronous digital systems

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    Diagnosing faults on operational synchronous digital system

    Electromation and Du Pont: The Next Generation

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    Electromation and Du Pont: The Next Generation

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    Attitudes of Mothers and Daughters Towards Menstrual Suppression

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    Recent biomedical advancements, cultural practices, and individual preferences have altered the ways in which biological process such as menstruation are perceived and managed. Increasingly, women are interested in suppressing menstruation to alleviate its negative symptoms, including bloating, menstrual cramps, fatigue, and irritability. This topic is especially relevant for adolescent girls, as mothers and daughters might have to negotiate attitudes towards daughters’ menstrual suppression. Therefore this study aims to examine how this topic is discussed and understood within the mother-daughter dyad. It is also important to consider how these attitudes are shaped by cultural background, ethnicity, socioeconomic class, and religion. Through this knowledge health care providers can have a more holistic understanding of how their patients’ view menstruation. If health care providers know these basic demographics and the perspectives on this issue, they can be better prepared in administering information and educating their patients. My data collection included literature review, a five category survey, and participant observation in a clinical setting. There were 72 mother-daughter pairs with a total of 144 participants that completed designated surveys for mothers and daughters that had a total of five categories emphasizing participant details, menstrual cycle, reproductive health history, attitudes towards their period and menstrual suppression. Through the experiences of my participants I have found that there is a great desire to learn more of menstrual suppression among both mothers and daughters and that there is some degree of influence of religion and ethnicity on perceptions of menstrual suppression in this population. Age on the other hand, turned out to not be an important factor shaping the positive or negative attitudes toward suppression

    Sensitivity analysis Progress report, 1 Mar. - 1 May 1967

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    Flow graph technique for calculating sensitivity coefficients for electric network

    Diversity in parasitic nematode genomes: the microRNAs of Brugia pahangi and Haemonchus contortus are largely novel

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    <b>BACKGROUND:</b> MicroRNAs (miRNAs) play key roles in regulating post-transcriptional gene expression and are essential for development in the free-living nematode Caenorhabditis elegans and in higher organisms. Whether microRNAs are involved in regulating developmental programs of parasitic nematodes is currently unknown. Here we describe the the miRNA repertoire of two important parasitic nematodes as an essential first step in addressing this question. <b>RESULTS:</b> The small RNAs from larval and adult stages of two parasitic species, Brugia pahangi and Haemonchus contortus, were identified using deep-sequencing and bioinformatic approaches. Comparative analysis to known miRNA sequences reveals that the majority of these miRNAs are novel. Some novel miRNAs are abundantly expressed and display developmental regulation, suggesting important functional roles. Despite the lack of conservation in the miRNA repertoire, genomic positioning of certain miRNAs within or close to specific coding genes is remarkably conserved across diverse species, indicating selection for these associations. Endogenous small-interfering RNAs and Piwi-interacting (pi)RNAs, which regulate gene and transposon expression, were also identified. piRNAs are expressed in adult stage H. contortus, supporting a conserved role in germline maintenance in some parasitic nematodes. <b>CONCLUSIONS:</b> This in-depth comparative analysis of nematode miRNAs reveals the high level of divergence across species and identifies novel sequences potentially involved in development. Expression of novel miRNAs may reflect adaptations to different environments and lifestyles. Our findings provide a detailed foundation for further study of the evolution and function of miRNAs within nematodes and for identifying potential targets for intervention
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