1,921 research outputs found

    An Overview of Health Law Research and an Annotated Bibliography

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    This analysis and the following bibliography are designed to meet the needs of researchers attempting to locate information in the field of health law. The analysis is written from the perspective of law librarians, but the same information retrieval problems apply to health administrators, hospital and medical counsel, and academic lawyers interested in health law and administration

    When Courts Make Law: How the International Criminal Tribunals Recast the Laws of War

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    This Article argues that states often tacitly delegate lawmaking authority and that the Security Council did so in the case of the Tribunals. Although the historical record cannot definitely prove its validity, this hypothesis is supported by evidence from other international courts that lawmaking by international judiciaries is widespread and accepted by states, even if formally proscribed. The Article suggests that states do not acknowledge this delegation, however, in order both to perpetuate the fiction of state hegemony over international norm generation and to provide a shield behind which international courts can make law without suffering paralyzing political pressure that would negate their ability to do so. As a normative matter, this Article argues that international judicial lawmaking is most appropriate when the relevant underlying treaties are old, where underlying conditions have changed, and where there is little prospect for the treaties\u27 revision. International judicial lawmaking can usefully modulate the contradictory demands of rule stability and flexibility in the face of changing conditions, a central challenge for all international institutions

    Mortality in patients with successful initial response to highly active antiretroviral therapy is still higher than in non-HIV-infected individuals.

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    Mortality in HIV-infected patients has decreased dramatically since the introduction of highly active antiretroviral therapy (HAART). We analyzed progression to death in a population of 3678 antiretroviral treatment-naive patients from the ATHENA national observational cohort from 24 weeks after the start of HAART. Mortality was compared with that in the general population in the Netherlands matched by age and gender. Only log-transformed CD4 cell count (hazard ratio [HR] = 0.50, 95% confidence interval [CI]: 0.40 to 0.61 per unit increase) and plasma viral load (HR = 0.30, 95% CI: 0.15 to 0.60, HIV RNA level or = 100,000 copies/mL) measured at 24 weeks and infection via intravenous drug use (IDU) (HR = 0.16, 95% CI: 0.10 to 0.26, non-IDU vs. IDU) were significantly associated with progression to death. For non-IDU patients with 600 x 10 CD4 cells/L and an HIV RNA level <100,000 copies/mL at 24 weeks, mortality was predicted to be 5.3 (95% CI: 3.5 to 8.4) and 10.4 (95% CI: 6.4 to 17.4) times higher than in the general population for 25-year-old men and women, respectively, and 1.15 (95% CI: 1.08 to 1.25) and 1.29 (95% CI: 1.16 to 1.50) times higher for 65-year-old men and women, respectively. Hence, mortality in HIV-infected patients with a good initial response to HAART is still higher than in the general population

    Tracing Hidden Herbivores: Time-Resolved Non-Invasive Analysis of Belowground Volatiles by Proton-Transfer-Reaction Mass Spectrometry (PTR-MS)

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    Root herbivores are notoriously difficult to study, as they feed hidden in the soil. However, root herbivores may be traced by analyzing specific volatile organic compounds (VOCs) that are produced by damaged roots. These VOCs not only support parasitoids in the localization of their host, but also may help scientists study belowground plant-herbivore interactions. Herbivore-induced VOCs are usually analyzed by gas-chromatography mass spectrometry (GC-MS), but with this off-line method, the gases of interest need to be preconcentrated, and destructive sampling is required to assess the level of damage to the roots. In contrast to this, proton-transfer-reaction mass spectrometry (PTR-MS) is a very sensitive on-line, non-invasive method. PTR-MS already has been successfully applied to analyze VOCs produced by aboveground (infested) plant parts. In this review, we provide a brief overview of PTR-MS and illustrate how this technology can be applied to detect specific root-herbivore induced VOCs from Brassica plants. We also specify the advantages and disadvantages of PTR-MS analyses and new technological developments to overcome their limitations

    ENERGETIC COSTS AND STRATEGIES OF POST‐JUVENAL MOLT IN AN EQUATORIAL BIRD, THE RUFOUS‐COLLARED SPARROW (ZONOTRICHIA CAPENSIS)

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    Abstract  ∙ Many tropical birds have slow‐paced life history strategies, exhibiting lower metabolic rates, reduced annual investment in reproduction, and longer lifespans relative to birds at higher latitudes. Life history strategies have been relatively well documented in adult individuals in the tropics, but we know comparatively little about the immature life history stage. Here we examine strategies of feather replacement (molt) and fattening in immature Rufous‐collared Sparrows (Zonotrichia capensis) in a high elevation equatorial population, following a parallel, previous study on an arctic congener, the White‐crowned Sparrow (Zonotrichia leucophrys gambelii). In captivity, Rufous‐ collared Sparrows incurred energetic costs of experimentally induced feather growth, similar to those previously described for Zonotrichia at higher latitudes. In contrast, free‐ranging immature Rufous‐collared Sparrows in natural molt had fat stores that declined over time, opposite to patterns evident in arctic Zonotrichia that fatten before migration. Equatorial birds in good condition molted more heavily (controlling for fat stores), suggesting that body condition limits the intensity of molt. Heavily molting equatorial sparrows also had lower amounts of fat (controlling for body condition), suggesting a trade‐off between allocation of resources to fat stores versus feather growth. Molt progressed slowly in Rufous‐collared Sparrows relative to previously described patterns in their arctic congener, which is concordant with a slower pace‐of‐life syndrome in tropical, as compared with high latitude, birds. Resumen ∙ Costos energéticos y estrategias de muda post‐juvenil en un ave ecuatorial, el Chingolo (Zonotrichia capensis) Muchas especies de aves tropicales presentan historias de vida lenta, exhibiendo bajas tasas metabólicas, esfuerzo reproductivo anual reducido, y mayor longevidad que las especies que habitan en latitudes más altas. La variación en historia de vida en especies tropicales ha sido bien documentada para individuos adultos, pero sabemos comparativa‐ mente poco de los individuos inmaduros. Aquí estudiamos las estrategias de muda y deposición de grasa en individuos inmaduros de Chingolo (Zonotrichia capensis) en una población ecuatorial de altura y comparamos los resultados con un estudio similar realizado en una población ártica del congénere Chingolo Coroniblanco (Zonotrichia leucophrys gambelii). En cautiverio, individuos juveniles de Z. capensis incurrieron costos energéticos debidos a la muda inducida, similar lo encontrado en Z. leucophrys gambelii. En contraste, Z. capensis inmaduros mudando en libertad presentaron depósitos de grasa que disminuyeron a lo largo del tiempo, lo opuesto a Z. l. gambelii, que deposita más grasa antes de migrar. Z. capensis inmaduros en buen estado nutricional (controlando por diferencias en deposición de grasa) mudaron de manera más intensa, lo que sugiere que el estado nutricional limita la muda. Individuos inmaduros de Z. capensis mudando de manera intensa presentaron menor cantidad de grasa depositada (controlando por diferencias en estado nutricional), lo que sugiere un balance entre la deposición de grasa y la muda. La muda fue más lenta en la población ecuatorial de Z. capensis comparado con la de Z. l. gambelii, lo que concuerda con lo esperado debido a la historia de vida más lenta en aves tropicales

    The Arts as a Teaching Tool and the Power of Collaboration and Co-teaching

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    Over the last seventeen years, an arts education initiative has transformed the dynamics of an isolated rural school into a model for rural arts access. Three teachers from Copper Basin High School began an avalanche of possibilities in 1997 when the Annenberg Rural Challenge Grant provided funding to begin a new era in a small rural school. Isolated by geographical boundaries and stifled by economical hardships since the closing of the copper mines in 1988, something had to be done. After a series of teacher in-services for visual strategies (using art as a teaching tool reflective of Gardner\u27s Multiple Intelligences), followed with collaborations between teachers and art consultants, students were led to a deeper understanding through problem solving, critical thinking, and creative explorations. After this experiment proved successful, in a grassroots self-supporting survival move, a non-profit organization was established and grants were obtained to continue and expand the work. In 2004, an unexpected corporate partnership with Glenn Springs Holdings, Inc. was established to provide funding and support to develop the Copper Basin Learning Center. This session examines the path that led to the Learning Center, challenges faced along the way, and what works in the program and why. There is a lot of talk on the educational forefront today concerning moving from STEM to STEAM, with the arts being a significant component. Discussion will include dispelling basic assumptions and developing a workable plan of action for incorporating the arts in the school curriculum

    Interference Effects Due to Commensurate Electron Trajectories and Topological Crossovers in (TMTSF)2ClO4

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    We report angle-dependent magnetoresistance measurements on (TMTSF)2ClO4 that provide strong support for a new macroscopic quantum phenomenon, the interference commensurate (IC) effect, in quasi-one dimensional metals. In addition to observing rich magnetoresistance oscillations, and fitting them with one-electron calculations, we observe a clear demarcation of field-dependent behavior at local resistance minima and maxima (versus field angle). Anticipated by a theoretical treatment of the IC effect in terms of Bragg reflections in the extended Brillouin zone, this behavior results from 1D-2D topological crossovers of electron wave functions as a function of field orientation.Comment: 14 page
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