Disentanglement and decoherence in two-spin and three-spin systems under dephasing

We compare disentanglement and decoherence rates within two-spin and three-spin entangled systems subjected to all possible combinations of local and collective pure dephasing noise combinations. In all cases, the bipartite entanglement decay rate is found to be greater than or equal to the dephasing-decoherence rates and often significantly greater. This sharpens previous results for two-spin systems [T. Yu and J. H. Eberly Phys. Rev. B 68, 165322 (2003)] and extends them to the three-spin context.Comment: 17 page

Penicillin Allergy Assessment and Skin Testing in the Outpatient Setting

Penicillin allergies are among of the most commonly reported allergies, yet only 10% of these patients are truly allergic. This leads to potential inadvertent negative consequences for patients and makes treatment decisions challenging for clinicians. Thus, allergy assessment and penicillin skin testing (PST) are important management strategies to reconcile and clarify labeled penicillin allergies. While PST is more common in the inpatient setting where the results will immediately impact antibiotic management, this process is becoming of increasing importance in the outpatient setting. PST in the outpatient setting allows clinicians to proactively de-label and educate patients accordingly so beta-lactam antibiotics may be appropriately prescribed when necessary for future infections. While allergists have primarily been responsible for PST in the outpatient setting, there is an increasing role for pharmacist involvement in the process. This review highlights the importance of penicillin allergy assessments, considerations for PST in the outpatient setting, education and advocacy for patients and clinicians, and the pharmacist’s role in outpatient PST

Molecular and chemical characterization of genes involved in maize cuticular wax biosynthesis

The primary surfaces of the arial parts of plants, and the surfaces of reproductive organs are covered by an extra cellular layer called the cuticle. The cuticle provides the foremost protection to the plant in order to adapt to the terrestrial environment. The cuticle composed of a biopolymer (cutin), which is embedded in a coating of cuticular waxes. Understanding the biochemical, genetic and physiological mechanisms for the biosynthesis of these cuticular waxes is relatively poor. This body of work has established methods for the chemical analysis of the cuticular waxes of maize plants. I have used these methods to chemically characterize cuticular waxes and intermediates of cuticular wax biosynthesis in mutant plants that show aberrant accumulation of these components. In addition, I have generated a yeast-based heterologous expression system for testing the biochemical and genetic properties of genes that are involved in cuticular wax biosynthesis. These accomplishments have set the stage for deciphering the complexity of cuticular wax biosynthesis

The continued value of disk diffusion for assessing antimicrobial susceptibility in clinical laboratories: Report from the Clinical and Laboratory Standards Institute Methods Development and Standardization Working Group

Expedited pathways to antimicrobial agent approval by the U.S. Food and Drug Administration (FDA) have led to increased delays between drug approval and the availability of FDA-cleared antimicrobial susceptibility testing (AST) devices.</jats:p

A Feud that Wasn't: Acetylcholine Evokes Dopamine Release in the Striatum

In this issue of Neuron, Threlfell et al. (2012) report that synchronous activation of cholinergic interneurons evokes striatal dopamine release by activating presynaptic nicotinic acetylcholine receptors. These findings call for a fundamental reevaluation of the long-standing view that dopamine and acetylcholine “feud” over control of striatal circuitry

Cancer patients’ experiences of living with venous thromboembolism: A systematic review and qualitative thematic synthesis

Background: Cancer-Associated thrombosis is common. Recommended treatment is daily injected low-molecular-weight heparin for 6months. Most studies focus on prophylaxis and treatment; few have explored patients’ experience. Aims To identify and synthesise the available literature concerning patients’ experience of cancer associated thrombosis. Design Systematic literature review and qualitative thematic synthesis. MethodsMEDLINE, Embase, CINAHL, PsychINFO (until 10/2016; limited to English) were searched. Eligible papers were qualitative studies of adult patients’ experience of cancer-associated thrombosis. Two researchers screened titles/abstracts/papers against inclusion criteria with recourse to a third for disagreements. Critical Appraisal Skills Programme qualitative checklist tool was used for quality appraisal. Results1397 articles were identified. Five qualitative studies (total n=92; age range 32 to 84 years) met the inclusion criteria. Participants had various cancer types. Most had advanced disease and were receiving palliative care. Four major themes emerged from the data: knowledge deficit (patients and clinicians); effects of cancer associated thrombosis (physical and psychological); effects of anticoagulation; coping strategies. ConclusionThe cancer journey is difficult in itself, but thrombosis was an additional, frightening and unexpected burden. Although the association between cancer and thromboembolism is well known, cancer patients are not educated routinely about the risk or warning symptoms/signs of thromboembolism which may otherwise be misattributed to the cancer by patient and clinician alike. This systematic review highlights the impact of cancer-associated thrombosis on the lives of cancer patients, and calls for education for patients and clinicians to be part of routine care, and further work to address this patient priority

Obesity Economics for the Western United States

Health Economics and Policy,

The Search for Virtue and the Role of Anti-Corruption Agencies : A Queensland Case Study

This paper deals with the ambiguous role played by one "heavy regulatory regime" and the complex relationships developed between this anti-corruption agency, the various governments in power after its creation and (only incidentally) with the modernisation of the police service in Queensland. The story of the modernisation of the Queensland police service is a remarkable one, involving as it does the disgrace and imprisonment of Police Commissioner Terry Lewis and - on unrelated corruption charges - several Ministers. This was linked to the disgrace of a Premier of one government linked to both events, whose party subsequently plunged to electoral defeat in 1989 after thirty years in office. More recently (February, 2001), Queensland has seen the resignation of a Deputy Premier and several Ministers of the opposing party after admitting electoral rorting associated with fraud and perjury. Apparently paradoxically, the party then went immediately to an election where it won a victory of unprecedented proportions. The common feature has been the impact of a judicial enquiry between 1987 and 1989 and the activities generated by the supervisory body created by that enquiry, the Criminal Justice Commission (CJC). This paper is in two parts: the first deals with the political context and administrative changes over the past decade; and the second focuses specifically on the operation of the Criminal Justice Commission within that context and its role in promoting modernisation of the police force

The Caddo Indian Burial Ground (3MN386), Norman, Arkansas

Human burials were exposed accidentally during construction of a city sewer treatment plant in Norman, Arkansas, in October 1988. Archeological salvage excavations in the days following, directed by Ann Early of the Arkansas Archeological Survey’s Henderson Research Station, identified two burials, a small cluster of residential features, and artifacts dating from the Archaic through Caddo periods. After discussions between the various agencies and groups involved, a new location was found for the sewer treatment plant. The human bone and associated grave goods were returned to the Caddo Tribe for reburial, and the site was covered up for protection. The site, 3MN386, originally named the Norman Sewer Plant site and now called the Caddo Indian Burial Ground in Norman, is part of a city park. The Southern Montgomery County Development Council has plans to install a series of signs along a walking path at the park to interpret the site. Site 3MN386 is located on a low terrace next to the confluence of Huddleston Creek and the Caddo River. Based on the distribution of chipped stone debris, the site was at least 1.5 hectares (almost 4 acres) in area, but the full extent of the site was never determined by archeological investigations. The archeological salvage excavations in 1988 were limited to a small area of 25 x 30 m where the burials and other features were uncovered. While artifacts diagnostic of Archaic and Fourche Maline periods were found at the site, the main use of the site was in the Mississippian period. Two Caddoan occupations between about AD 1250-1500 are indicated based on the materials associated with these features: an earlier residential use of the site that left the remains of a large circular house with hearth and a burned ash floor deposit; and a later use of the site as a cemetery

Two cases of fungal keratitis caused by Metarhizium anisopliae

We present two cases of keratitis due to Metarhizium anisopliae in geographically separated areas of the United States. The isolates were microscopically similar but morphologically different and were identified by ribosomal DNA sequencing. Both isolates had low minimum inhibitory concentration (MIC) values to caspofungin and micafungin, but high MIC values to amphotericin B. The morphologic and antifungal susceptibility differences between the two isolates indicate possible polyphylogeny of the group. Keywords: Metarhizium, Fungal keratitis, Keratomycosis, Antifungal susceptibilit