Combat and Warfare in the Early Paleolithic and Medically Unexplained Musculo-Facial Pain in the 21st Century War Veterns and Active-Duty Military Personnel

In a series of recent articles, we suggest that family dentists, military dentists and psychiatrists with expertise in posttraumatic stress disorder (especially in the Veterans Health Administration) are likely to see an increased number of patients with symptomatic jaw-clenching and early stages of tooth- grinding (Bracha et al., 2005). Returning warfighters and other returnees from military deployment may be especially at risk for high rates of clenching- induced masticatory muscle disorders at early stages of incisor grinding. The literature we have recently reviewed strongly supports the conclusion that clenching and grinding may primarily be a manifestation of experiencing extreme fear or severe chronic distress (respectively). We have recently reviewed the clinical and paleoanthropological literature and have noted that ancestral warfare and ancestral combat, in the early Paleolithic Environment of Evolutionary Adaptedness (EEA) may be a neglected factor explaining the conservation of the archaic trait of bite-muscle strengthening. We have hypothesized that among ancestral warriors, jaw clenching may have rapidly strengthened the two primary muscles involved in biting, the masseter muscles and the much larger temporalis muscles. The strengthening of these muscles may have served the purpose of enabling a stronger, deeper, and therefore more lethal, defensive bite for early Paleolithic humans. The neuroevolutionary perspective presented here may be novel to many dentists. However, it may be useful in patient education and in preventing progression from jaw-clenching to chronic facial pain

Flow boiling heat transfer of a non-azeotropic mixture inside a single microchannel

This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the Process Intensification Network, the Institution of Mechanical Engineers, the Heat Transfer Society, HEXAG - the Heat Exchange Action Group, and the Energy Institute, ASME Press, LCN London Centre for Nanotechnology, UCL University College London, UCL Engineering, the International NanoScience Community, www.nanopaprika.eu.This study moves from the need to study flow boiling of zeotropic mixture in microchannels. In the recent years much attention has been paid to the possible use of fluorinated propene isomers for the substitution of high-GWP refrigerants. The available HFOs (hydrofluoroolefins) cannot cover all the air-conditioning, heat pump, and refrigeration systems when used as pure fluids because their thermodynamic properties are not suitable for all operating conditions and therefore some solutions may be found using blends of refrigerants, to satisfy the demand for a wide range of working conditions. In the present paper a mixture of R1234ze(E) and R32 (0.5/0.5 by mass) has been studied. The local heat transfer coefficient during flow boiling of this mixture in a single microchannel with 0.96 mm diameter is measured at a pressure of 14 bar, which corresponds to a bubble temperature of 26.3°C. The flow boiling data taken in the present test section are discussed, with particular regard to the effect of heat flux, mass velocity and vapor quality. The heat transfer coefficients are compared against some predicting models available in the literature. Furthermore, the new experimental data are compared to flow boiling data of pure R1234ze(E) and pure R32 to analyze the heat transfer penalization due to the mass transfer resistance of this zeotropic mixture

Reevaluating the Management of Chronic Temporomandibular Pain Are We Treating PTSD with Debridement and Lavage?

n/

Relationship between fatty liver and glucose metabolism: A cross-sectional study in 571 obese children

BACKGROUND AND AIMS: Early onset type 2 diabetes mellitus (T2DM) is associated with obesity, insulin resistance and impaired beta-cell function. Non-alcoholic fatty liver disease (NAFLD) may be an independent risk factor for T2DM. We investigated the relationship between NAFLD and glucose metabolism in a large sample of obese children. METHODS AND RESULTS: A total of 571 obese children (57% males and 43% females) aged 8-18 years were consecutively studied at a tertiary care centre specialised in paediatric obesity. Liver ultrasonography was used to diagnose NAFLD after exclusion of hepatitis B and C and alcohol consumption. Oral-glucose tolerance testing (OGTT) was performed; insulin sensitivity was evaluated by using the insulin sensitivity index (ISI) and beta-cell function by using the ratio between the incremental areas under the curve (AUC) of insulin and glucose (incAUCins/incAUCglu). A total of 41% of the obese children had NAFLD. Impaired glucose tolerance or T2DM was present in 25% of the children with NAFLD versus 8% of those without it (p<0.001). Children with NAFLD had higher body mass index (BMI), fasting glucose, 120-min OGTT glucose, incAUCins/incAUCglu and lower ISI as compared with children without NAFLD (p</=0.002). At bootstrapped multivariable median regression analysis controlling for gender, age, pubertal status and BMI, NAFLD was an independent predictor of 120-min OGTT glucose and ISI, but not of incAUCins/incAUCglu. Similar findings were obtained using continuous liver steatosis as the predictor, instead of dichotomous NAFLD. CONCLUSION: NAFLD was present in 41% of our obese children and was associated with higher insulin resistance, but not with impaired beta-cell function

Psychometric properties of the Fatigue Severity Scale in obese patients

BACKGROUND: The aim of this study was to examine the psychometric properties of the Fatigue Severity Scale (FSS) to verify whether this instrument is a valid tool to measure fatigue in obese patients, and to examine the prevalence of fatigue in obese patients. METHODS: Before and after a three-week residential multidisciplinary integrated weight reduction program, 220 patients were asked to fill in the questionnaires: FSS, Profile of Mood States (Fatigue-Inertia subscale, POMS-Fatigue, and Vigor-Activity subscale, POMS-Vigor), and the Obesity-Related Well-Being (ORWELL-97). A subsample of 50 patients completed the questionnaire within two days. RESULTS: The prevalence of fatigue using a cut-off value of 4 for the FSS score was 59%. Correlations were found between FSS and POMS-Fatigue and -Vigor scores (r = 0.58 and 0.53, respectively). A relation was also found between FSS and ORWELL97 (r = 0.52, 0.42 to 0.61). From the factorial analysis only 1 factor was extracted explaining 63% of variance, with factor loading values ranging from 0.71 (item 7) to 0.87 (item 6). Intraclass Correlation Coefficient was 0.89 (0.82 to 0.94), while the agreement as measured using the Standard Error of Measurement was 0.43 (0.36 to 0.54) corresponding to 13% (11 to 17%). Cronbach’s alpha values ranged from 0.94 to 0.93. The internal responsiveness of FSS was comparable to the ORWELL97 (Standardized Response Mean = 0.50 and 0.44, respectively). CONCLUSIONS: Fatigue is an important and frequent symptom in obese patients and therefore should be routinely assessed in both research and clinical practice. This can be achieved using the FSS, which is a short, simple, valid and reliable tool for assessing and quantifying fatigue in obese patients

Density functional theory of vortex lattice melting in layered superconductors: a mean-field--substrate approach

We study the melting of the pancake vortex lattice in a layered superconductor in the limit of vanishing Josephson coupling. Our approach combines the methodology of a recently proposed mean-field substrate model for such systems with the classical density functional theory of freezing. We derive a free-energy functional in terms of a scalar order-parameter profile and use it to derive a simple formula describing the temperature dependence of the melting field. Our theoretical predictions are in good agreement with simulation data. The theoretical framework proposed is thermodynamically consistent and thus capable of describing the negative magnetization jump obtained in experiments. Such consistency is demonstrated by showing the equivalence of our expression for the density discontinuity at the transition with the corresponding Clausius-Clapeyron relation.Comment: 11 pages, 4 figure

Two-photon Lithography for 3D Magnetic Nanostructure Fabrication

Ferromagnetic materials have been utilised as recording media within data storage devices for many decades. Confinement of the material to a two dimensional plane is a significant bottleneck in achieving ultra-high recording densities and this has led to the proposition of three dimensional (3D) racetrack memories that utilise domain wall propagation along nanowires. However, the fabrication of 3D magnetic nanostructures of complex geometry is highly challenging and not easily achievable with standard lithography techniques. Here, by using a combination of two-photon lithography and electrochemical deposition, we show a new approach to construct 3D magnetic nanostructures of complex geometry. The magnetic properties are found to be intimately related to the 3D geometry of the structure and magnetic imaging experiments provide evidence of domain wall pinning at a 3D nanostructured junction

Why They Fight: Combat Motivation in the Iraq War

With the recent lightning swift combat successes of Operation IRAQI FREEDOM, there may be a tendency to view with awe the lethality of U.S. technology and training. The researchers, however, argue that the true strength of America\u27s military might lies not in its hardware or high-tech equipment, but in its soldiers. Dr. Leonard Wong and his colleagues traveled to Iraq to see what motivated soldiers to continue in battle, to face extreme danger, and to risk their lives in accomplishing the mission. As a means of comparison, they began by interviewing Iraqi Regular Army prisoners of war to examine their combat motivation and unit dynamics. The researchers then interviewed U.S. combat troops fresh from the fields of battle to examine their views. What they found was that today\u27s U.S. soldiers, much like soldiers of the past, fight for each other. Unit cohesion is alive and well in today\u27s Army. Yet, Dr. Wong and his fellow researchers also found that soldiers cited ideological reasons such as liberation, freedom, and democracy as important factors in combat motivation. Today\u27s soldiers trust each other, they trust their leaders, they trust the Army, and they also understand the moral dimensions of war. This year marks the 30th anniversary of the all-volunteer Army. This monograph is a celebration of the success of that radical idea and the transformation of the U.S. Army from a demoralized draft army, to a struggling all-volunteer force, to a truly professional Army.https://press.armywarcollege.edu/monographs/1787/thumbnail.jp

Thrombolysis with tissue plasminogen activator in acute myocardial infarction: no additional benefit from immediate percutaneous coronary angioplasty

A randomised trial of 367 patients with acute myocardial infarction was performed to determine whether an invasive strategy combining thrombolysis with recombinant tissue-type plasminogen activator (rTPA), heparin, and acetylsalicylic acid, and immediate percutaneous transluminal coronary angioplasty (PTCA) would be superior to a noninvasive strategy with the same medical treatment but without immediate angiography and PTCA. Intravenous infusion of 100 mg rTPA was started within 5 h after onset of symptoms (median 156 min). Angiography was performed 6-165 min later in 180 out of 183 patients allocated to the invasive strategy; 184 patients were allocated to the non-invasive strategy. Immediate PTCA reduced the percentage stenosis of the infarc

Optimization of hybrid sol-gel coating for dropwise condensation of pure steam

We developed hybrid organic-inorganic sol-gel silica coatings with good durability in harsh environment (high temperatures, high vapor velocities) and with slightly hydrophobic behavior, sufficient to promote dropwise condensation (DWC) of pure steam. DWC is a very promising mechanism in new trends of thermal management and power generation systems to enhance the heat transfer during condensation as compared to film-wise condensation (FWC). The sol-gel coatings have been prepared from methyl triethoxy silane (MTES) and tetraethyl-orthosilicate (TEOS) and deposited on an aluminum substrate. The coatings were optimized in terms of precursor ratio and annealing temperature highlighting potentials and limits of such mixtures. A comprehensive surface characterization before and after saturated steam condensation tests has been performed and related to the thermal measurements for evaluating the heat transfer augmentation as compared to FWC obtained on untreated aluminum surfaces. The results showed that the developed hybrid organic-inorganic sol-gel silica coatings are promising DWC promoters