322 research outputs found

    Phase Diagram of Multilayer Magnetic Structures

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    Multilayer "ferromagnet-layered antiferromagnet" (Fe/Cr) structures frustrated due to the roughness of layer interfaces are studied by numerical modeling methods. The "thickness-roughness" phase diagrams for the case of thin ferromagnetic film on the surface of bulk antiferromagnet and for two ferromagnetic layers separated by an antiferromagnetic interlayer are obtained and the order parameter distributions for all phases are found. The phase transitions nature in such systems is considered. The range of applicability for the "magnetic proximity model" proposed by Slonczewski is evaluated.Comment: 8 pages, 8 figure

    Theoretical investigations of a highly mismatched interface: the case of SiC/Si(001)

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    Using first principles, classical potentials, and elasticity theory, we investigated the structure of a semiconductor/semiconductor interface with a high lattice mismatch, SiC/Si(001). Among several tested possible configurations, a heterostructure with (i) a misfit dislocation network pinned at the interface and (ii) reconstructed dislocation cores with a carbon substoichiometry is found to be the most stable one. The importance of the slab approximation in first-principles calculations is discussed and estimated by combining classical potential techniques and elasticity theory. For the most stable configuration, an estimate of the interface energy is given. Finally, the electronic structure is investigated and discussed in relation with the dislocation array structure. Interface states, localized in the heterostructure gap and located on dislocation cores, are identified

    Concept of Suicide: Neurophysiological/Genetic Theories and Possible Oxytocin Relevance

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    The suicidal behavior is regarded as the act by which a person seeks to take his life, being aware of the consequences of his action. In our review, besides describing the main introductory aspects for the concept of suicide, we focus our attention on the main neurophysiological and genetical mechanisms relevant for this extremely difficult to manage and controversial behavior. Moreover, considering the latest interests in the current literature on the relevance of central oxytocin to various superior cognitive behaviors, we will also make a short description on how important effects of oxytocin could be in the context of suicidal behavior.Суїцидальна поведінка – це дії, в результаті яких особа намагається позбавити себе життя, усвідомлюючи наслідки таких дій. У даному огляді, окрім опису основних загальних аспектів концепції суїциду, ми концентрували увагу на основних нейрофізіологічних та генетичних аспектах, котрі мають відношення до цього вкрай важко контрольованого та повного протиріч типу поведінки. Окрім того, враховуючи велику цікавість, яку викликає в сучасній літературі задіяність центральної окситоцинової системи в контроль когнітивної поведінки вищих типів, ми надали короткий опис того, наскільки ефекти окситоцину можуть бути важливими в контексті суїцидальної поведінки

    LibraRing: An Architecture for Distributed Digital Libraries Based on DHTs

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    Abstract. We present a digital library architecture based on distributed hash tables. We discuss the main components of this architecture and the protocols for offering information retrieval and information filtering functionality. We present an experimental evaluation of our proposals.

    Time-Sensitive User Profile for Optimizing Search Personlization

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    International audienceThanks to social Web services, Web search engines have the opportunity to afford personalized search results that better fit the user’s information needs and interests. To achieve this goal, many personalized search approaches explore user’s social Web interactions to extract his preferences and interests, and use them to model his profile. In our approach, the user profile is implicitly represented as a vector of weighted terms which correspond to the user’s interests extracted from his online social activities. As the user interests may change over time, we propose to weight profiles terms not only according to the content of these activities but also by considering the freshness. More precisely, the weights are adjusted with a temporal feature. In order to evaluate our approach, we model the user profile according to data collected from Twitter. Then, we rerank initial search results accurately to the user profile. Moreover, we proved the significance of adding a temporal feature by comparing our method with baselines models that does not consider the user profile dynamics

    Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight

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    From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-based studies with 187 million participants. Changes in the prevalence of underweight and total obesity, and to a lesser extent severe obesity, are largely driven by shifts in the distribution of BMI, with smaller contributions from changes in the shape of the distribution. In East and Southeast Asia and sub-Saharan Africa, the underweight tail of the BMI distribution was left behind as the distribution shifted. There is a need for policies that address all forms of malnutrition by making healthy foods accessible and affordable, while restricting unhealthy foods through fiscal and regulatory restrictions

    Genetic and phenotypic characterization of NKX6‐2‐related spastic ataxia and hypomyelination

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    Background and purpose Hypomyelinating leukodystrophies are a heterogeneous group of genetic disorders with a wide spectrum of phenotypes and a high rate of genetically unsolved cases. Bi‐allelic mutations in NKX6‐2 were recently linked to spastic ataxia 8 with hypomyelinating leukodystrophy. Methods Using a combination of homozygosity mapping, exome sequencing, and detailed clinical and neuroimaging assessment a series of new NKX6‐2 mutations in a multicentre setting is described. Then, all reported NKX6‐2 mutations and those identified in this study were combined and an in‐depth analysis of NKX6‐2‐related disease spectrum was provided. Results Eleven new cases from eight families of different ethnic backgrounds carrying compound heterozygous and homozygous pathogenic variants in NKX6‐2 were identified, evidencing a high NKX6‐2 mutation burden in the hypomyelinating leukodystrophy disease spectrum. Our data reveal a phenotype spectrum with neonatal onset, global psychomotor delay and worse prognosis at the severe end and a childhood onset with mainly motor phenotype at the milder end. The phenotypic and neuroimaging expression in NKX6‐2 is described and it is shown that phenotypes with epilepsy in the absence of overt hypomyelination and diffuse hypomyelination without seizures can occur. Conclusions NKX6‐2 mutations should be considered in patients with autosomal recessive, very early onset of nystagmus, cerebellar ataxia with hypotonia that rapidly progresses to spasticity, particularly when associated with neuroimaging signs of hypomyelination. Therefore, it is recommended that NXK6‐2 should be included in hypomyelinating leukodystrophy and spastic ataxia diagnostic panels
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