VOICE - a spectrogram computer display package

A real-time spetrogram instrument has been developed to provide an inexpensive and field-portable instrument for the analysis of animal sounds. The instrument integrates a computer graphics display package with a PC-AT computer equipped with an A/D board and a digital signal processing board. It provides a real-time spectrogram display of frequencies up to 50kHz in a variety of modes: a running display, a signal halted on screen, successive expanded views of the signal. The signal amplitude may also be displayed. Portions of the scrolled data may be saved to disk file for future viewing, or as part of a database collection. The screen display may be manipulated to adapt to special needs. Program source listings are included in the text.Funding was provided by the Office of Naval Research through Grant Nos. N00014-88-K-0273 and N00014-87-K-0236, the National Institutes of Health through Grant No.1 R29 NS25290, and the Andrew W. Mellon Foundation

Digital Signal Processing Research Program

Contains table of contents for Section 2, an introduction and reports on fourteen research projects.U.S. Navy - Office of Naval Research Grant N00014-91-J-1628Defense Advanced Research Projects Agency/U.S. Navy - Office of Naval Research Grant N00014-89-J-1489MIT - Woods Hole Oceanographic Institution Joint ProgramLockheed Sanders, Inc./U.S. Navy Office of Naval Research Contract N00014-91-C-0125U.S. Air Force - Office of Scientific Research Grant AFOSR-91-0034U.S. Navy - Office of Naval Research Grant N00014-91-J-1628AT&T Laboratories Doctoral Support ProgramNational Science Foundation Fellowshi

Digital Signal Processing Research Program

Contains table of contents for Section 2, an introduction, reports on sixteen research projects and a list of publications.Bose CorporationMIT-Woods Hole Oceanographic Institution Joint Graduate Program in Oceanographic EngineeringAdvanced Research Projects Agency/U.S. Navy - Office of Naval Research Grant N00014-93-1-0686Lockheed Sanders, Inc./U.S. Navy - Office of Naval Research Contract N00014-91-C-0125U.S. Air Force - Office of Scientific Research Grant AFOSR-91-0034AT&T Laboratories Doctoral Support ProgramAdvanced Research Projects Agency/U.S. Navy - Office of Naval Research Grant N00014-89-J-1489U.S. Navy - Office of Naval Research Grant N00014-93-1-0686National Science Foundation FellowshipMaryland Procurement Office Contract MDA904-93-C-4180U.S. Navy - Office of Naval Research Grant N00014-91-J-162

Mechanism of cellular rejection in transplantation

The explosion of new discoveries in the field of immunology has provided new insights into mechanisms that promote an immune response directed against a transplanted organ. Central to the allograft response are T lymphocytes. This review summarizes the current literature on allorecognition, costimulation, memory T cells, T cell migration, and their role in both acute and chronic graft destruction. An in depth understanding of the cellular mechanisms that result in both acute and chronic allograft rejection will provide new strategies and targeted therapeutics capable of inducing long-lasting, allograft-specific tolerance

A new cervical-thoracic orthosis: Clinical report of seven cases

A new cervical-thoracic orthosis is described which provides cervical-thoracic stabilization, and is possibly less intrusive, less conspicuous, and more comfortable than other orthoses currently available. It rests and pivots on the wearer\u27s shoulder, thereby transferring the weight of the head, via the shoulder pivot, to the wearer\u27s shoulder and midsection. Our admittedly limited results show that the orthosis is relatively cool and comfortable, easy to clean, and aesthetically pleasing as it can be worn under clothing and concealed from general view. The orthosis is formed from one continuous piece of a suitably rigid material and generally conforms to the contours of the wearer\u27s body. One size fits most users; however, it can be customized to conform to the contours of the wearer, even while the wearer is positioned in a corrective posture. The orthosis can also be used to incrementally adjust the position of the wearer\u27s head or the curvature of the wearer\u27s spine. A preliminary process for mass producing the orthosis has been demonstrated with a view toward a more sophisticated method of manufacture. Physicians have prescribed the orthosis for seven patients, and the initial qualitative results presented here are quite encouraging

Antecedents, psychiatric characteristics and follow-up of adolescents hospitalized for suicide attempt of overwhelming suicidal ideation.

To evaluate the socio-demographic as well as the health and psychiatric profiles of adolescents hospitalised for suicide attempt or overwhelming suicide ideation and to assess repetition of suicide attempt over a period of 18 months. Between April 2000 and September 2001, all patients aged 16 to 21 years admitted to the University Hospitals of Geneva and Lausanne for suicide attempt or ideation were included in the study. At this time (T0) semi-structured face to face interviews were conducted to identify socio-demographic data, mental health and antecedents regarding suicidal conducts. Current psychiatric status was assessed with the MINI (Mini International Neuropsychiatric Instrument). At T1 and T2, reassessments included psychiatric status (MINI) as well as lifestyles, socio-professional situation and suicidal behaviours. At T0, 269 subjects met the study criteria, among whom 83 subjects (56 girls and 27 boys) left the hospital too quickly to be involved or refused to participate in the study (final sample at T0: 149 girls; 37 boys). The participation rate at T1 and T2 was respectively 66% and 62% of the original sample. The percentage of adolescents meeting the criteria for psychiatric diagnoses (91%) was high: affective disorder (78%); anxiety disorder (64%); substance use disorder (39%); eating disorder (9%); psychotic disorder (11%); antisocial personality (7%) with most subjects (85%) having more than one disorder. Around 90% of the subjects interviewed at T1, and/or T2, had received follow-up care after their hospitalisation, either by a primary care physician or a psychotherapist or both. Two subjects died of violent death and 18% made a further suicide attempt. Most adolescents hospitalised for suicidal episodes suffer from psychiatric problems which should be addressed by a careful psychiatric assessment, followed up if needed by a structured after care plan