Multiple Quaternary erosion and infill cycles in overdeepened basins of the northern Alpine foreland

The cumulative effect of repeated extensive glaciations represents a poorly constrained component in the understanding of landscape evolution in mid-latitude mountain ranges such as the Alps. Timing, extent, and paleo-climatic conditions of these glaciations are generally poorly understood due to the often-fragmentary character of terrestrial Quaternary records. In this context, the sedimentary infills of subglacial basins may serve as important archives to complement the Quaternary stratigraphy over several glacial--interglacial cycles. In this study, sedimentary facies, valley-fill architecture, and luminescence dating are used to describe nine erosional and depositional cycles (Formations A--I) in the Lower Glatt valley, northern Switzerland. These cycles can be related to the `Birrfeld' Glaciation (~ MIS2), the `Beringen' Glaciation (~ MIS6), and up to three earlier Middle Pleistocene glaciations that can be tentatively correlated to the regional glaciation history. Evidence suggests that deep bedrock trough incision and/or partial re-excavation last occurred mainly during the `Beringen' and `Habsburg' Glaciations. Second-order, 'inlaid' glacial basins document separate glacier re-advances during the Beringen Glaciation. The arrangement of subglacial basins in the Glatt valley with different sub-parallel or bifurcating bedrock troughs, re-excavated segments, and inlaid basins document changes in the magnitude and the spatial focus of subglacial erosion over time. The Glatt valley may thus serve as a key example for the glacial landscape evolution in many other repeatedly glaciated forelands

Phytotherapeutic and naturopathic adjuvant therapies in otorhinolaryngology

Phytotherapeutic pharmaceuticals and herbal medicinal products with its roots in classical phytotherapeutic medicine have a well-established role in otolaryngological therapy, especially for diseases of the upper airways and acute and chronic infections. A thorough selection and application could mean huge benefit for the patient, in particular in cases with contraindications, chemo- and antibiotic resistance or patient request. Besides, it might spare other medications. Phytotherapeutic pharmaceuticals must fulfil the same criteria of quality, effectiveness and harmlessness of evidence-based medicine like chemical pharmaceuticals, although they are often prescribed due to its well established or traditional based use. This review focuses on phytotherapeutic therapies well established within the European Community for otolaryngologic disease patterns by referring to clinical studies or meta-analysis

The Chilling Effects of Algorithmic Profiling: Mapping the Issues

In this article, we provide an overview of the literature on chilling effects and corporate profiling, while also connecting the two topics. We start by explaining how profiling, in an increasingly data-rich environment, creates substantial power asymmetries between users and platforms (and corporations more broadly). Inferences and the increasingly automated nature of decision-making, both based on user data, are essential aspects of profiling. We then connect chilling effects theory and the relevant empirical findings to corporate profiling. In this article, we first stress the relationship and similarities between profiling and surveillance. Second, we describe chilling effects as a result of state and peer surveillance, specifically. We then show the interrelatedness of corporate and state profiling, and finally spotlight the customization of behavior and behavioral manipulation as particularly significant issues in this discourse. This is complemented with an exploration of the legal foundations of profiling through an analysis of European and US data protection law. We find that while Europe has a clear regulatory framework in place for profiling, the US primarily relies on a patchwork of sector-specific or state laws. Further, there is an attempt to regulate differential impacts of profiling via anti-discrimination statutes, yet few policies focus on combating generalized harms of profiling, such as chilling effects. Finally, we devise four concise propositions to guide future research on the connection between corporate profiling and chilling effects. Horizon 2020(H2020)707404Effective Protection of Fundamental Rights in a pluralist worl

Subglacial emplacement of tills and meltwater deposits at the base of overdeepened bedrock troughs

The sedimentary infill of subglacially eroded bedrock troughs in the Alps are underexplored archives for the timing, extent and character of Pleistocene glaciations but may contain excellent records of the Quaternary landscape evolution over several glacial-interglacial cycles. The onset of sedimentation in these bedrock troughs is often reflected by diamicts and gravels directly overlying bedrock in the deepest basin segments. Subglacial or proglacial depositional environments have been proposed for these coarse-grained basal units but their characteristics and origin remain controversial. This article presents results from drill cores that recovered a coarse-grained basal unit in a major buried bedrock-trough system in the Lower Glatt Valley, northern Switzerland. The excellent core recovery allowed a detailed study combining macroscopic, microscopic and geochemical methods and gives unprecedented insights into the transition from erosion to deposition in overdeepened bedrock troughs. These results show that the basal infill comprises diamicts, interpreted as subglacial tills, separated by thin sorted interbeds, originating from subglacial cavity deposition. The stacking may thus represent repeated switching between a coupled and decoupled ice-bed-interface indicating an ever-transforming mosaic of subglacial bed conditions. Decoupling in response to high basal water pressures is probably promoted by the confined subglacial hydraulic conditions resulting from the bedrock acting as aquitard, the narrow reverse sloping outlet and a large catchment area. While stratigraphic and lithological evidence suggests that erosion and the onset of basal sedimentation occurred during the same glaciation, different scenarios for the relative timing of infilling in relation to formation and glaciation of the bedrock trough are discussed. Overlying deltaic and glaciolacustrine sediments suggest deposition during subsequent deglaciation of the bedrock trough. The basal sediment characteristics are in agreement with previous reports in hydrogeological and seismic exploration and suggest the occurrence of similar basal successions in other subglacially overdeepened basin in the Alps and elsewhere