Designing a new vanillin Schiff base (Z)-4-((2-hydroxy-3-methoxy benzylidene)amino)-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one: Synthesis, characterization, crystal structure and biological studies

1110-1116Novel Schiff base containing antipyrine and o-vanillin has been synthesized and characterized by various physicochemical techniques such as FTIR, UV-Vis, CHN, 1Hand 13C NMR spectral studies. The thermal behavior of the title compound has been examined with Thermogravimetric-Differential thermal analysis (TG-DTA). The structural properties have been further examined by single crystal X-ray diffraction studies. The X-ray diffraction data shows that the compound contains four molecules in the asymmetric unit. Antifungal activity of the compound has been carried out for four different fungi Aspergillus niger, Aspergillus flavus, Aspergillus terrus and Fusarium Sp at three different concentrations, whereas the compound shows significant activity against the fungi Aspergillus niger

Designing a new vanillin Schiff base (Z)-4-((2-hydroxy-3-methoxy benzylidene)amino)-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one: Synthesis, characterization, crystal structure and biological studies

Novel Schiff base containing antipyrine and o-vanillin has been synthesized and characterized by various physicochemical techniques such as FTIR, UV-Vis, CHN, 1Hand 13C NMR spectral studies. The thermal behavior of the title compound has been examined with Thermogravimetric-Differential thermal analysis (TG-DTA). The structural properties have been further examined by single crystal X-ray diffraction studies. The X-ray diffraction data shows that the compound contains four molecules in the asymmetric unit. Antifungal activity of the compound has been carried out for four different fungi Aspergillus niger, Aspergillus flavus, Aspergillus terrus and Fusarium Sp at three different concentrations, whereas the compound shows significant activity against the fungi Aspergillus niger.

Crystal Growth and Characterization of a New NLO Material: p-Toluidine p-Toluenesulfonate

Single crystals of p-Toluidine p-Toluenesulfonate (PTPT), an organic nonlinear optical (NLO) material, have been grown by slow evaporation method at room temperature using ethanol as solvent. The crystal system was confirmed from the single crystal X-ray diffraction analysis. The functional groups were identified using FTIR spectroscopy. UV-Vis-NIR spectrum showed that the UV cut-off wavelength of PTPT occurs at 295 nm and it has insignificant absorption in the wavelength region of 532–800 nm. The SHG efficiency of PTPT was measured by employing Kurtz and Perry powder technique using a Q-switched mode locked Nd: YAG laser emitting 1064 nm for the first time and it was found to be 52% of standard KDP. Thermal and mechanical properties of PTPT were examined by TG/DTA and Vickers microhardness test, respectively.</jats:p

Ethyl 6-amino-5-cyano-2,4-bis­(4-methyl­phen­yl)-4H-pyran-3-carboxyl­ate

In the title compound, C23H22N2O3, the pyran ring adopts a twisted boat conformation. The tolyl rings and carboxyl­ate group are attached to the pyran ring with torsion angles of −77.1 (2), 59.5 (3) and 17.8 (3)°, respectively. The ethyl group is disordered over two orientations with a site-occupancy ratio of 0.508 (5):0.492 (5). In the crystal, mol­ecules are linked by N—H⋯N and N—H⋯O hydrogen bonds, generating a chain running the a axis. Weak C—H⋯O, C—H⋯N and C—H⋯π inter­actions are also observed

4-Chloro­anilinium 3-carb­oxy­prop-2-enoate

In the title compound, C6H7ClN+·C4H3O4 −, the cations and anions lie on mirror planes and hence only half of the mol­ecules are present in the asymmeric unit. The 4-chloro­anilinium cation and hydrogen maleate anion in the asymmetric unit are each planar and are oriented at an angle of 15.6 (1)° to one another and perpendicular to the b axis. A characterestic intra­molecular O—H⋯O hydrogen bond, forming an S(7) motif, is observed in the maleate anion. In the crystal, the cations and anions are linked by N—H⋯O hydrogen bonds, forming layers in the ab plane. The aromatic rings of the cations are sandwiched between hydrogen-bonded chains and rings formed through the amine group of the cation and maleate anions, leading to alternate hydro­phobic (z = 0 or 1) and hydro­philic layers (z = 1/2) along the c axis

Bis(2,6-diamino­pyridinium) bis­(hydrogen oxalate) monohydrate

The asymmetric unit of the title compound, 2C5H8N3 +·2C2HO4 −·H2O, contains two crystallographically independent 2,6-diamino­pyridinium cations, a pair of hydrogen oxalate anions and a water mol­ecule. Both 2,6-diamino­pyridinium cations are planar, with maximum deviations of 0.011 (2) and 0.015 (1) Å, and are protonated at the pyridine N atoms. The hydrogen oxalate anions adopt twisted conformations and the dihedral angles between the planes of their carboxyl groups are 31.01 (11) and 63.48 (11)°. In the crystal, the cations, anions and water mol­ecules are linked via O—H⋯O and N—H⋯O hydrogen bonds, forming a three-dimensional network

Polymer Nanocomposite Materials and Shape Memory Applications-A Review

AbstractThere is tremendous increase in research activity and publications in Polymer matrix composite materials and nanostructures in the last few years, this article is an attempt to identify the topics that are most relevant to Shape Memory Polymer Composite (SMPC) materials and review representative journal publications that are related to those topics. Articles covering developments in Fabrication methods and integrated structural and non-structural functions characterization are emphasized. Structural functions include mechanical properties like strength, stiffness, fracture toughness, and damping, while non–structural functions include electrical and/or thermal conductivity, sensing and actuation, energy harvesting/storage, self-healing capability, electromagnetic interference (EMI) shielding, recyclability and biodegradability. Many of these recent developments are associated with Actuating mechanisms of Shape memory polymer composite materials and corresponding advances in nanomaterials and nanostructures, as are many of the articles reviewed. The article concludes with a discussion of recent applications of Shape memory Polymers and structures, such as morphing aircraft wings, Industrial valves, seals etc., and in biomedical SMPs for dispensing drugs and diagnostics, and optically transparent impact absorbing structures. Several suggestions regarding future research needs are also presented

Evaluation of drug likeliness of (Z)-4-((4-hydroxy-3-methoxy benzylidene)amino)-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one by computational analysis against coronavirus and T-cells of immune system

559-567The Schiff base (Z)-4-((4-hydroxy-3-methoxy benzylidene)amino)-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazole-3- one (VAP) has been synthesized by the condensation of 4-aminoantipyrine with vanillin and and characterized by FT-IR, 1H and 13C NMR spectroscopy. The structure of the synthesized compound has been confirmed by single-crystal X-ray diffraction studies, which shows that four units of the compound are in an asymmetric part of the crystal structure. The potential activity of synthesized Schiff base compound has been determined by molecular docking with T-cells (6bnk) and against Coronavirus (6lu7)

Tensile behaviour and characterization of amine treated nanoclay reinforced epoxy/polyurethane blends and composites for shape memory applications

435-442Polymer nanocomposites are the better choice for most of the applications because of its less weight and tailorability to suit different applications. Several nanocomposites have been fabricated with nanoparticles reinforcement and fibre reinforcement. But most of them were made to satisfy few criteria or one or two functions. Shape memory polymers composites (SMPCs) and blends exhibit novel properties that are different from the conventional materials and thus can be utilized in various applications. These composites are needed for applications such as smart clothing, flexible displays, stretchable circuits, strain gauges, implantable devices, high-stroke microelectromechanical systems (MEMS), and actuators where both mechanical properties and shape memory properties are important. The processing and characterization of these materials with nanoparticles produces better mechanical properties. Epoxy is the resin having good mechanical properties, when blended with polyurethane and nanoparticles fillers exhibit shape memory properties. This paper gives the fabrication and characterization methods for shape memory polymer composites developed with amine treated nanoclay as reinforcement and analyses tensile behaviour and moisture absorption and surface characteristics. Fourier transform infrared spectroscopy (FTIR) is used to identify the bond and functional groups and thermo gravimetric analysis (TGA) and differential scanning calorimetry (DSC) are done to identify the glass transition temperature and scanning electron microscope (SEM) analysis for studying the morphology and tensile test is done to test the stress-strain behaviour. The reinforcement has shown significant improvement in glass transition temperature and mechanical properties compared to pure shape memory polymers