Evaluation of 2ME-RDE test for detection of antibodies simultaneously against Actinobacillus pleuropneumoniae serotypes 1 to 12 in pig sera

Mittal, K. R.; Achacha, M.; Bourdon, S.; Fenwick, B.. (2000). Evaluation of 2ME-RDE test for detection of antibodies simultaneously against Actinobacillus pleuropneumoniae serotypes 1 to 12 in pig sera. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/161157

Absence of a set of plasmid-encoded genes is predictive of reduced pathogenic potential in Brachyspira hyodysenteriae

International audienceAbstractThe gene content of 14 strains of the intestinal spirochaete Brachyspira hyodysenteriae was compared using a DNA microarray. A consistent difference occurred in a block of four genes on the ~36 Kb plasmid, with these being present in six virulent strains and absent in eight strains with reduced pathogenic potential. These genes encoded a predicted radical S-adenosylmethionine domain protein, a glycosyl transferase group 1-like protein, an NAD dependant epimerase and a dTDP-4-dehydrorhamnose 2–5 epimerase: they may be involved in rhamnose biosynthesis and glycosylation. The absence of these plasmid genes in B. hyodysenteriae isolates is predictive of reduced pathogenic potential