FOUNDATION STRENGTHENING AND GROUTING BY MEANS OF JET PILES FOR A 9+1-STOREY BUILDING WITH STRENGTHENED-CONCRETE FRAMING

The reinforced concrete frame building on the area of 17 x 150 sq.m consists of a cellar, ground floor and 9+1 storeys. The pillars were founded on solitary reinforced concrete blocks. The given vertical supporting system is horizontally connected by flexible, reinforced concrete sheets for ceiling. This configuration was not adequate to withstand, or balance the ensued uneven settlements arisen by the response of the alternating subsoil under the different loads from the pillars. At frames 14. to 27., however, - which were founded on weak silty fine sand of varying thickness (0.5 to 3.0 m) - the safety factor against failure was calculated to n=1, instead of n=2.77 that had to be prescribed. The goal was to transfer the loads from the silty fine sand onto the Kiscelli clay, which has excellent bearing capacity at 5 to 6 m deeper levels. The first part of the reading to be presented deals with the unavoidable geotechnical exploration, laboratory testing, determination of the intermittent and final time dependent parameters of the jet-propulsion work, the evaluation of the in situ bearing capacity trials and, of the strength analysis of the undisturbed samples having been taken from the jet piles. The second section informs about the design and accomplishment of the work, and concludes with the settlement monitoring results that verified the success. The measurements proved that the settlements stopped at the prescribed limits and, the reckoned safety factors against failure widely surpass the n=2.77 value required by the standard for this case

A süllő, a kősüllő és hibridjük megmaradásának és növekedésének összehasonlító vizsgálata intenzív körülmények közt = Comparative investigation of the survival and growth of pikeperch, volga-pikeperch and their hybrid under intensive conditions

Megfigyeltük, hogy a süllő a természetes ívási idő előtt 1-2 hónappal akár egészen drasztikus hőmérsékletemeléssel (10 oC/három nap) is szaporítható állapotba hozható. Az ovulált ikra elszórásának megakadályozására, és a fejések szinkronizálhatóságára kifejlesztettük a petevezető elzárásának egy kíméletes módszerét. Megállapítottuk, hogy a hibridek közül csak a süllő×kősüllő hibrid jöhet szóba a termelés számára, mert a fordított hibrid túlságosan kis lárvamérete (~3,3 mm) nagyon nehézkessé teszi az "indítást". Elsőként a Pannon Egyetem és SZIE kutatóinak sikerült süllő, és kősüllő spermát mélyfagyasztani és felolvasztás után azokkal termékenyítést végezni. Megfigyelésünk szerint a süllő növekedési és takarmány-felhasználási paraméterekben felülmúlta a hibridet. Úgy találtuk viszont, hogy a hibrid könnyebben szoktatható tápra, mint a süllő. Az oxigénhiány tűréssel kapcsolatos vizsgálataink nem támasztják alá azt az általánosságban elfogadott elképzelést, miszerint a kősüllő a süllőnél ellenállóbb faj lenne. Különféle olaj-kiegészítéseket alkalmaztunk haltápon és megvizsgáltuk azok hatását a süllők növekedésére, és testösszetételére. A vizsgált 14 zsírsavból 5 esetben statisztikailag igazolható különbséget lehetett kimutatni. Tíz számszerű és 38 morfometriai bélyeget felhasználva a szülői fajok és a hibridek elkülönítését biztosító határozó bélyegeket írtunk le. | We found, that the pikeperch can be taken into the stage of ready for spawning even by drastic increase of water temperature (10 oC/three days) 1-2 months before the natural spawning season We developed a careful method for closing the oviduct in order to stop the spontaneous release of eggs and to synchronize the strippings. We concluded that from the hybrids of pikeperch and Volga pikeperch only that one has practical prosperity where the pikeperch is the female, since the larval size of the reciprocal hybrid is much too small (~3.3 mm), making the starter feeding difficult in farms. Researchers of the University of Pannonia and Szt. Istvan University were the first to carry out deep freezing of pikeperch and Volga pikeperch sperm, and fertilizing with it after thawing up. According to our studies the pikeperch is superior to its hybrid with Volga pikeperch regarding growth and feed conversion, but the hybrid proved to be easier to train on pelleted feed than the pure pikeperch. Our experiments on the oxygen-depletion tolerance do not support that broadly accepted view that the Volga pikeperch is more resistant than the pikeperch. We studied the effects of different lipid (oil) supplements on the growth and body composition of the pikeperch. From the fourteen studied fatty acids 5 has been significantly modified

Thrombotic Thrombocytopenic Purpura, Moschcowitz Syndrome

The authors present a case of a 16-year-old boy, who was referred to the hospital due to thrombocytopenia, anemia, proteinuria and hyperbilirubinemia. Based on the clinical picture and the laboratory data, thrombotic thrombocytopenic purpura (TTP) was diagnosed. The adequate therapy was immediately started. TTP is quite a rare entity. The etiology and the pathogenesis are not well defined. The authors summarize the different pathomechanisms, which may play a role in the development of TTP. Similarity to the hemolytic uremic syndrome (HUS), therapeutic possibilities, prognosis and the outcome are also discussed. The importance of the early diagnosis of TTP in childhood, and life-saving effect of the adequate treatment are emphasized

Comparative study of X-ray computed tomography and conventional X-ray methods in the diagnosis of swimbladder infection of eel caused by Anguillicola crassus

To date, swimbladder lesions due to Anguillicola crassus infection of the European eel Anguilla anguilla have so far been studied only by conventional X-ray methods. This is the first study to report the use of computerised tomography (CT) for studying lesions induced by anguillicolosis. Of 50 eels caught by electrofishery from Lake Balaton, Hungary, in autumn 2002 and pre-selected by a conventional X-ray method, 22 specimens were examined with a Siemens Somatom Plus S40 spiral CT scanner. Tomograms, radiographs and photographs of 5 of these, showing anguillicolosis-induced swimbladder lesions of varying severity, are presented. Computerised tomograms provide information on the inner structure, air content and wall thickness of the swimbladder as well as on the number of worms it contains. When the swimbladder is not severely affected or not completely filled with worms, computerised tomography provides adequate data on the shape of the swimbladder, thickness of the swimbladder wall and the location of worms in the lumen. However, in more severe cases, i.e. when the swimbladder is tightly packed with worms or contains no air as a result of wallthickening, this method fails to determine the number and location of helminths or the thickness of the swimbladder wall

Improper Supplementation Habits of Folic Acid Intake by Hungarian Pregnant Women: Improper Recommendations

Background: Neural tube defects (NTDs) are some of the most common congenital anomalies. Proper folic acid supplementation is a dominant risk factor, which has been shown to decrease the incidence of NTDs. In Canada, the incidence of neuroblastoma has presented a considerable decrease of 60% as a result of enrichment cereal grain flours with synthetic folic acid. The aim of this study was to investigate the effect of folic acid intake by pregnant women on the incidence of NTDs and neuroblastoma. Methods: Regular folic acid intake has been recommended to pregnant women in Hungary since the eighties of the last century by health visitors eventually raking effect as an official protocol which had been released in 1997. During 2001, 2002 and 2003. folic acid intake habits of pregnant women were evaluated by health visitors, proving to be successful in collecting data front 95.06% of the pregnant women. The incidence of NTDs has been registered by the Hungarian National Centre of Epidemiology, Department of Human Genetics and Teratology. The Pediatric Cancer Registry provided the incidence of neuroblastoma in children. Results: Consistent findings revealed a regular intake of supplementary folic acid products by 68.71% of the pregnant women. Out of these. 93.13% of pregnant women who were taking folic acid, started the supplementation after their 7 weeks of pregnancies, a time designated as the completion period of the development of the neural tube. The dose of folic acid supplementation was evaluated as less than 5 mg/day in 84.75% of the pregnant women. In Hungary, the incidence of NTDs has remained constant, while the incidence of neuroblastoma has shown constant slight increase in spite of the introduction of folic acid supplementation in 1997. Conclusions: Based on our experience, folic acid supplementation was initiated after the recognition of pregnancy and its application in a dose of lower than 5 mg/day neither decreased the incidence of NTDs nor did it have an effect on the neuroblastoma incidence. It is implicated that proper folic acid supplementation, which is started front the conception. can be achieved only with the enrichment of cereal grain flours

A gyermekkori Ewing szarkómával szerzett magyarországi tapasztalataink

Magyarországon évente kb. 7-9 új Ewing szarkómás gyermeket diagnosztizálunk. Jelen munkánk célja az volt, hogy az Országos Gyermektumor Regiszter adatait felhasználva megvizsgáljuk a magyarországi Ewing szarkómás gyermekek prezentációs tüneteit, a klinikai paramétereket, a prognosztikai faktorokat, a terápiás és a túlélési eredményeket 1992 és 2002 közötti 11 éves periódusban. A fenti időszakban 88 új beteg került diagnosztizálásra, a fiú – leány arány 1,05 : 1 volt, az átlagéletkor 11 év 7 hónapnak bizonyult. A két leggyakoribb prezentációs tünet a lokális fájdalom és duzzanat voltak. 38 betegünkben hosszú csöves csontra lokalizálódott a megbetegedés, 29 gyermekben a Ewing szarkóma a csípő tájékról indult ki és 21 esetben valamely egyéb testtájékról. A betegeink közel egyharmadánál (29/88) már a diagnózis felállításakor áttétek voltak kimutathatóak. A fent nevezett időszakban három kemoterápiás protokollt alkalmaztunk Magyarországon: a CWS, az EICESS/CESS és 1999. decembere óta az Euro-EWING 99 protokollt. A 88 beteg 37,5%-nál (33/88) észleltünk recidívát átlagosan 22,4 hónappal a primer diagnózis felállítása után. A 88 betegből 45 jelenleg is él, az átlag követési idő 28,6 hónap. Az összes beteg 5-éves kumulatív túlélési valószínűsége 48,06±5,9%, a 10 éves 42,91±6,3%. A metasztázissal rendelkező betegek 5 és 8 éves túlélése 19,91±9,4%, a metasztázis nélküliek 5 éves túlélése 60,23±6,9%, míg a 10 éves 52,82±7,8%. A hazai eredmények megközelítik a nemzetközi adatokat, azonban törekednünk kell a diagnózis korai felállítására és ezáltal a kimondottan rossz prognózisú primer metasztatikus esetek számának csökkentésére. The number of newly diagnosed children in a year with Ewing’s sarcoma is 7-9 in Hungary. The aim of our study was to evaluate the presenting symptoms, clinical features, prognostic risk factors and treatment results of children’s Ewing’s sarcoma in Hungary using data from the National Childhood Cancer Registry in a 11 years-long period between 1992 and 2002. In this period, 88 new patients were diagnosed, the male-female ratio was 1,05:1 and the mean age was 11 years 7 months. The two most common presenting symptoms were local pain and swallowing. Tumor was located in the pelvis area in 29 patients, in the extremities in 38 and other sites in 21 cases. Almost one third of our patients (29/88) had metastasis at the time of the diagnosis. In this time period, three different protocols were used for treatment: CWS, EICESS/CESS and since December 1999 Euro-EWING 99. 37,5% of our patients (33/88) had relapse with a mean of 22,4 months after the diagnosis. 45 children are still alive, the median follow-up time is 28,6 months. The overall survival (OS) of all patients (n=88) was 48,06±5,9% at 5 years and 42,91±6,3% at 10 years. Patients with metastasis had OS 19,91±9,4% at 5 and at 8 years. The 5-year OS of children without metastasis was 60,23±6,9%, and 52,82±7,8% at 10 years. The Hungarian data are similar to international results, but we have to try to decrease the number of the primary metastatic cases with early diagnosis

A Tihanyi Formáció a Balaton környékén: típusszelvény, képződési körülmények, rétegtani jellemzés.

Revisiting the Tihany, Fehérpart section, overviewing archive data, comparison with successions of nearby wells, well-logs, stratigraphic data and results of the high-resolution seismic surveys on Lake Balaton resulted a coherent picture on the depositional environment, age, stratigraphic correlation and palaeogeographic connections of the Tihany Formation. In addition to former analyses of grain-size distributions, carbonate and clay content, the sedimentary structures were investigated, a pilot study of gamma-ray measurements on the field was carried out and several orders of cyclicity were demonstrated. Besides previous palaeontological studies new fossils were collected, determined and magnetic polarity of the rocks were measured. The Tihany, Fehérpart section is correlated with the Spiniferites tihanyensis dinoflagellate, the MN11 micromammal and the Limnocardium decorum sublittoral mollusc biozones. It shows normal magnetic polarity. It is underlain by open lacustrine, reverse polarity shales of the Congeria praerhomboidea zone, and is overlain by layers indicative of the Prosodacnomya zone. The latter is well definied by the radiometric age (7.9 Ma) of the overlying volcano sedimentary suite. Therefore the Fehérpart section was deposited either 8.1–8.0 Ma (C4An.2n) or 8.3–8.2 Ma (C4Ar.1n chron) ago. The Tihany Formation was deposited in a variety of palaeoenvironments related to deltas entering Lake Pannon. It is built up of parasequences, i.e. shallowing up successions from below wave base to lake level generated by sediment accumulation. Parasequences were formed on the delta front or in inter-distributary bays to delta-plain swamps and distributary channels. Beyond the high frequency lake-level and partly autocyclic environmental fluctuations, most likely climatically induced fourth-order lake-level changes of about 15–30 m amplitude occurred, resulting in minor transgressions followed by repeated progradation of deltaic lobes. Although the Tihany (as well as the very alike Somló) Formation is found along the rim of the hills currently, during its origin it was deposited in the same way as the Újfalu Formation known only from the subsurface of deep basins. The dynamics of deltaic settings feeding to Lake Pannon can be understood by studying the Tihany Formation in outcrops. The only difference among the two formations might be in the number of overlying delta cycles and their thickness. Both numbers were determined by rate of subsidence smaller at basement highs where Tihany Formation accumulated than at basin areas where Újfalu Formation was definied. It is suggested here to include Tihany (and Somló) beds as members of the Újfalu Formation. Fourth-order sequence boundaries were recognized between the overlying progradational deltaic bodies. In the vicinity of Tihany no evidences of lake-level drops were revealed, but elsewhere small incised-valley fills point to minor lake-level drops. Overall regression interrupted by transgressive events continued on the study area until the shelf edge of Lake Pannon shifted as far to the south as 50-60 km, i.e. at about 8 Ma ago. Since then flooding events became rare and small in amplitude, then the area became a terrestrial plain. Fluvial deposits are not known from the direct vicinity, but travertines formed in small freshwater ponds fed by karst springs. The transition from lacustrine to terrestrial palaeoenvironments is part of the overall normal regression as a result of high sediment input to Lake Pannon. Large incised valleys or other evidences of recurring terrestrial conditions which could be related to third-order sequence boundaries mappable all over the Pannonian Basin were identified neither in Tihany nor in Újfalu Formations

Robust and Accurate -- Compositional Architectures for Randomized Smoothing

Randomized Smoothing (RS) is considered the state-of-the-art approach to obtain certifiably robust models for challenging tasks. However, current RS approaches drastically decrease standard accuracy on unperturbed data, severely limiting their real-world utility. To address this limitation, we propose a compositional architecture, ACES, which certifiably decides on a per-sample basis whether to use a smoothed model yielding predictions with guarantees or a more accurate standard model without guarantees. This, in contrast to prior approaches, enables both high standard accuracies and significant provable robustness. On challenging tasks such as ImageNet, we obtain, e.g., $80.0\%$ natural accuracy and $28.2\%$ certifiable accuracy against $\ell_2$ perturbations with $r=1.0$. We release our code and models at https://github.com/eth-sri/aces.Comment: Presented at the ICLR 2022 Workshop on Socially Responsible Machine Learnin