Effect of Deflagration-to-Detonation Transition on Pulse Detonation Engine Impulse

A detonation tube was built to study the deflagration-to-detonation transition (DDT) process and the impulse generated when combustion products exhaust into the atmosphere. The reactants used were stoichiometric ethylene and oxygen mixture with varying amounts of nitrogen present as diluent. The effects of varying the initial pressure from 30 kPa to 100 kPa were studied, as were the effects of varying the diluent concentration from 0% to 73.8% of the total mixture. Measurements were carried out with the tube free of obstacles and with three different obstacle configurations. Each obstacle configuration had a blockage ratio of 0.43. It was found that the inclusion of obstacles dramatically lowered the DDT times and distances as compared to the no obstacle configuration. The obstacles were found to be particularly effective at inducing DDT in mixtures with low pressures and with high amounts of diluent. At the lowest pressures tested (30 kPa), obstacles reduced the DDT time and distance to approximately 12.5% of the no obstacle configuration values. The obstacles also allowed DDT to occur in mixture compositions of up to 60% diluent, while DDT was not achieved with more than 30% diluent in the no obstacle configuration. A ballistic pendulum arrangement was utilized, enabling direct measurement of the impulse by measuring the tube's deflection. Additional means of impulse comparison consisted of integrating the pressure over the front wall of the tube. Impulse measurements were then compared with a theoretical model and were found to fit well cases that did not contain internal obstacles. The inclusion of obstacles allowed DDT to occur in mixtures with high amounts of diluent where DDT was not observed to occur in the cases without obstacles. Roughly 100% more impulse was produced in the obstacle configurations as compared to the no obstacle configuration under these conditions. In instances where DDT occurred in the no obstacle configuration, the use of obstacle configurations lowered the impulse produced by an average of 25%. For cases where no obstacles were used and DDT occurred, the pressure derived impulses (pressure impulse) and impulses determined from the ballistic pendulum (ballistic impulses) are similar. For cases were obstacle configurations were tested, pressure impulses were more than 100% higher on average than ballistic impulses. This difference exists because the pressure model neglects drag due to the obstacle configurations

Motivation as a predictor of outcomes in school-based humanistic counselling

Recent years have seen a growth in the provision of counselling within UK secondary schools, and research indicates that it is associated with significant reductions in psychological distress. However, little is known about the moderators and mediators of positive therapeutic benefit. In the field of adult mental health, motivation has been found to be one of the strongest predictors of therapeutic outcomes, and it was hypothesised that this may also be a predictor of outcomes for young people in school-based counselling services. To assess the relationship between young people’s motivation for counselling and its effectiveness within a secondary school setting. Eighty-one young people (12 - 17 years old) who attended school-based humanistic counselling services in Scotland. Clients completed a measure of motivation for counselling at the commencement of their therapeutic work and a measure of psychological wellbeing at the commencement and termination of counselling. Motivation for counselling was not found to be significantly related to outcomes. The results indicate that the association between motivation and outcomes may be weaker in young people as compared with adults. However, a number of design factors may also account for the non-significant findings: insufficient participants, marginal reliability of the motivation measure and social desirability effects

Database Search Strategies for Proteomic Data Sets Generated by Electron Capture Dissociation Mass Spectrometry

Large data sets of electron capture dissociation (ECD) mass spectra from proteomic experiments are rich in information; however, extracting that information in an optimal manner is not straightforward. Protein database search engines currently available are designed for low resolution CID data, from which Fourier transform ion cyclotron resonance (FT-ICR) ECD data differs significantly. ECD mass spectra contain both z-prime and z-dot fragment ions (and c-prime and c-dot); ECD mass spectra contain abundant peaks derived from neutral losses from charge-reduced precursor ions; FT-ICR ECD spectra are acquired with a larger precursor m/z isolation window than their low-resolution CID counterparts. Here, we consider three distinct stages of postacquisition analysis: (1) processing of ECD mass spectra prior to the database search; (2) the database search step itself and (3) postsearch processing of results. We demonstrate that each of these steps has an effect on the number of peptides identified, with the postsearch processing of results having the largest effect. We compare two commonly used search engines: Mascot and OMSSA. Using an ECD data set of modest size (3341 mass spectra) from a complex sample (mouse whole cell lysate), we demonstrate that search results can be improved from 630 identifications (19% identification success rate) to 1643 identifications (49% identification success rate). We focus in particular on improving identification rates for doubly charged precursors, which are typically low for ECD fragmentation. We compare our presearch processing algorithm with a similar algorithm recently developed for electron transfer dissociation (ETD) data

Robustness of Fractional Quantum Hall States with Dipolar Atoms in Artificial Gauge Fields

The robustness of fractional quantum Hall states is measured as the energy gap separating the Laughlin ground-state from excitations. Using thermodynamic approximations for the correlation functions of the Laughlin state and the quasihole state, we evaluate the gap in a two-dimensional system of dipolar atoms exposed to an artificial gauge field. For Abelian fields, our results agree well with the results of exact diagonalization for small systems, but indicate that the large value of the gap predicted in [Phys. Rev. Lett. 94, 070404 (2005)] was overestimated. However, we are able to show that the small gap found in the Abelian scenario is dramatically increased if we turn to non-Abelian fields squeezing the Landau levels

Physical Activity and Mental Well-being in a Cohort Aged 60–64 Years

Introduction: Although evidence suggests physical activity (PA) may be associated with mental well-being at older ages, it is unclear whether some types of PA are more important than others. The purpose of this study is to investigate associations of monitored total PA under free-living conditions, self-reported leisure-time PA (LTPA), and walking for pleasure with mental well-being at age 60–64 years. Methods: Data on 930 (47%) men and 1,046 (53%) women from the United Kingdom MRC National Survey of Health and Development collected in 2006–2011 at age 60–64 were used in 2013–2014 to test the associations of PA (PA energy expenditure and time spent in different intensities of activity assessed using combined heart rate and acceleration monitors worn for 5 days, self-reported LTPA, and walking for pleasure) with the Warwick-Edinburgh Mental Well-being Scale (WEMWBS; range, 14–70). Results: In linear regression models adjusted for gender, long-term limiting illness, smoking, employment, socioeconomic position, personality, and prior PA, those who walked for >1 hour/week had mean WEMWBS scores 1.47 (95% CI=0.60, 2.34) points higher than those who reported no walking. Those who participated in LTPA at least five times/month had WEMWBS scores 1.25 (95% CI=0.34, 2.16) points higher than those who did not engage in LTPA. There were no statistically significant associations between free-living PA and WEMWBS scores. Conclusions: In adults aged 60–64 years, participation in self-selected activities such as LTPA and walking are positively related to mental well-being, whereas total levels of free-living PA are not

Analytical Model for the Impulse of Single-Cycle Pulse Detonation Tube

An analytical model for the impulse of a single-cycle pulse detonation tube has been developed and validated against experimental data. The model is based on the pressure history at the thrust surface of the detonation tube. The pressure history is modeled by a constant pressure portion, followed by a decay due to gas expansion out of the tube. The duration and amplitude of the constant pressure portion is determined by analyzing the gasdynamics of the self-similar flow behind a steadily moving detonation wave within the tube. The gas expansion process is modeled using dimensional analysis and empirical observations. The model predictions are validated against direct experimental measurements in terms of impulse per unit volume, specific impulse, and thrust. Comparisons are given with estimates of the specific impulse based on numerical simulations. Impulse per unit volume and specific impulse calculations are carried out for a wide range of fuel–oxygen–nitrogen mixtures (including aviation fuels) of varying initial pressure, equivalence ratio, and nitrogen dilution. The effect of the initial temperature is also investigated. The trends observed are explained using a simple scaling analysis showing the dependency of the impulse on initial conditions and energy release in the mixture

Investigation of the Coupling Potential by means of S-matrix Inversion

We investigate the inelastic coupling interaction by studying its effect on the elastic scattering potential as determined by inverting the elastic scattering $S$-matrix. We first address the effect upon the real and imaginary elastic potentials of including excited states of the target nucleus. We then investigate the effect of a recently introduced novel coupling potential which has been remarkably successful in reproducing the experimental data for the $^{12}$C+$^{12}$C, $^{12}$C+$^{24}$Mg and $^{16}$O+$^{28}$Si reactions over a wide range of energies. This coupling potential has the effect of deepening the real elastic potential in the surface region, thereby explaining a common feature of many phenomenological potentials. It is suggested that one can relate this deepening to the super-deformed state of the compound nucleus, $^{24}$Mg.Comment: 12 pages with 3 figure

Genomic donor cassette sharing during VLRA and VLRC assembly in jawless vertebrates

Lampreys possess two T-like lymphocyte lineages that express either variable lymphocyte receptor (VLR) A or VLRC antigen receptors. VLRA+ and VLRC+ lymphocytes share many similarities with the two principal T-cell lineages of jawed vertebrates expressing the αβ and γδ T-cell receptors (TCRs). During the assembly of VLR genes, several types of genomic cassettes are inserted, in step-wise fashion, into incomplete germ-line genes to generate the mature forms of antigen receptor genes. Unexpectedly, the structurally variable components of VLRA and VLRC receptors often possess partially identical sequences; this phenomenon of module sharing between these two VLR isotypes occurs in both lampreys and hagfishes. By contrast, VLRA and VLRC molecules typically do not share their building blocks with the structurally analogous VLRB receptors that are expressed by B-like lymphocytes. Our studies reveal that VLRA and VLRC germ-line genes are situated in close proximity to each other in the lamprey genome and indicate the interspersed arrangement of isotype-specific and shared genomic donor cassettes; these features may facilitate the shared cassette use. The genomic structure of the VLRA/VLRC locus in lampreys is reminiscent of the interspersed nature of the TCRA/TCRD locus in jawed vertebrates that also allows the sharing of some variable gene segments during the recombinatorial assembly of TCR genes

The role of psychometrics in individual differences research in cognition: A case study of the AX-CPT

Investigating individual differences in cognition requires addressing questions not often thought about in standard experimental designs, especially regarding the psychometric properties of the task. Using the AX-CPT cognitive control task as a case study example, we address four concerns that one may encounter when researching the topic of individual differences in cognition. First, we demonstrate the importance of variability in task scores, which in turn directly impacts reliability, particularly when comparing correlations in different populations. Second, we demonstrate the importance of variability and reliability for evaluating potential failures to replicate predicted correlations, even within the same population. Third, we demonstrate how researchers can turn to evaluating psychometric properties as a way of evaluating the feasibility of utilizing the task in new settings (e.g., online administration). Lastly, we show how the examination of psychometric properties can help researchers make informed decisions when designing a study, such as determining the appropriate number of trials for a task