Properties of Neutral Charmed Mesons in Proton--Nucleus Interactions at 70 GeV

The results of treatment of data obtained in the SERP-E-184experiment "Investigation of mechanisms of the production of charmed particles in proton-nucleus interactions at 70 GeV and their decays" by irradiating the active target of the SVD-2 facility consisting of carbon, silicon, and lead plates, are presented. After separating a signal from the two-particle decay of neutral charmed mesons and estimating the cross section for charm production at a threshold energy {\sigma}(c\v{c})=7.1 \pm 2.4(stat.) \pm 1.4(syst.) \mub/nucleon, some properties of D mesons are investigated. These include the dependence of the cross section on the target mass number (its A dependence); the behavior of the differential cross sections d{\sigma}/dpt2 and d{\sigma}/dxF; and the dependence of the parameter {\alpha} on the kinematical variables xF, pt2, and plab. The experimental results in question are compared with predictions obtained on the basis of the FRITIOF7.02 code.Comment: 9 pages, 9 figures,3 table

Clinical-Laboratory Effectiveness of Immune-Replacement Therapy of Hemorrhagic Fever with Renal Syndrome

Currently, hemorrhagic fever with renal syndrome (HFRS) remains the most common natural focal disease of viral etiology in the Russian Federation. Effective antiviral drugs have not yet been developed. Pathogenetic and symptomatic drugs are mainly used in the treatment of HFRS.The aim of the study was to evaluate the clinical and laboratory effectiveness of intravenous gabriglobin in the treatment of moderate forms of HFRS.Materials and methods. The study included 22 patients with a diagnosis “HFRS of moderate severity” in the febrile stage of the disease. In the febrile period of HFRS, patients of the main group (n=10) were given gabriglobin via intravenous route at a dose of 0.1 g/kg per day along with pathogenetic therapy. The course of treatment was 2–3 infusions. The control group (n=12) received only pathogenetic therapy.Results and conclusions. As a result of the studies, the clinical and laboratory efficacy of intravenous administration of gabriglobin in the treatment of patients with moderate-grade HFRS was revealed, which was manifested by a decrease in the duration of the febrile period by 2.1 days, the severity of oliguria and a decrease in the duration of thrombocytopenia by 3.5 days compared with the group of patients receiving only pathogenetic therapy

Observation of narrow baryon resonance decaying into pKs0pK^0_s in pA-interactions at 70GeV/c70 GeV/c with SVD-2 setup

SVD-2 experiment data have been analyzed to search for an exotic baryon state, the $\Theta^+$-baryon, in a $pK^0_s$ decay mode at $70 GeV/c$ on IHEP accelerator. The reaction $pA \to pK^0_s+X$ with a limited multiplicity was used in the analysis. The $pK^0_s$ invariant mass spectrum shows a resonant structure with $M=1526\pm3(stat.)\pm 3(syst.) MeV/c^2$ and $\Gamma < 24 MeV/c^2$. The statistical significance of this peak was estimated to be of $5.6 \sigma$. The mass and width of the resonance is compatible with the recently reported $\Theta^+$- baryon with positive strangeness which was predicted as an exotic pentaquark ($uudd\bar{s}$) baryon state. The total cross section for $\Theta^+$ production in pN-interactions for $X_F\ge 0$ was estimated to be $(30\div120) \mu b$ and no essential deviation from A-dependence for inelastic events $(\sim A^{0.7})$ was found.Comment: 8 pages, 7 figures, To be submitted to Yadernaya Fizika. v3-v5 - Some references added, minor typos correcte

Фатальное течение гриппа А / H1N1 / 09, осложненного генерализованной нозокомиальной инфекцией

A fatal case of swine flu (А / H1N1 / 09) complicated by generalized nosocomial infection.Фатальное течение гриппа А / H1N1 / 09, осложненного генерализованной нозокомиальной инфекцией

Потенцирование общей мультимодальной анестезии контактным лазерным воздействием на организм в области красного диапазона действия при высоких ампутациях нижних конечностей

Objective. The aim of the study is to develop a technique of potentiating traditional multimodal anesthesia with contact laser exposure to the body in the red range (650 nm) in patients with critical lower limb ischemia (CLI).Materials and methods. Multimodal anesthesia in the main group was performed with the potentiation of modern laser technology in 70 to 94 years old 35 patients [7 (20.0 %) women and 28 (80.0 %) men] with CLI and associated diseases. As a comparison group, a retrospective group of 23 patients was selected who underwent a high amputation of the lower extremities without potentiation of multimodal anesthesia with laser blood radiation. Multimodal anesthesia was additionally potentiated with quantum hemotherapy sessions. Sessions were carried out using a fifth-generation semiconductor contact laser irradiation of blood LASPOT (PRC) in the form of a wristwatch with an additional effect on the acupuncture points Nei-Guan, Tun-li – the heart meridian, connection with the inner world, Ling-dao – the meridian hearts, the road of the spirit. The first session was performed to patients before surgery — a duration of 15 minutes; the second — during surgery — a duration of 30 minutes.Results. The obtained data on the shifts of peripheral hemodynamic parameters at the stages of surgical interventions in patients of both groups practically did not demonstrate significant differences from the baseline values, reflecting the adequacy of the degree of anesthesiological protection. In patients of the main group, central hemodynamic indices: the cardiac index (CI) significantly increased from 2.81 ± 0.49 to 3.15 ± 0.58 (p &lt; 0.05) l/min∙m2, and total peripheral vascular resistance (TPVR) decreased from 1587.5 ± 494.3 to 1492.7 ± 427.8 dyn∙s∙cm-5. In patients of the comparison group, CI increased during surgery from 2.83 ± 0.53 to 3.02 ± 0.35 l/min∙m2, and at the end of the operation it returned to baseline. Potentiation of multimodal anesthesia with modern laser technologies in patients of the main group made it possible to reduce during surgical interventions the average dose of fentanyl, which was 0.98 ± 0.12 mcg/kg/h, while in patients of the comparison group, the consumption of fentanyl was 3.28 ± 0.18 mcg/kg/h (with traditional combined general anesthesia, the flow rate of fentanyl during surgery is on average 5–12 mcg/kg/h or more).Conclusion. The method of potentiation of the traditional scheme of general combined anesthesia with optical radiation of the red range (650 nm) allows to achieve more pronounced effects of hemodynamic control, makes it possible to reduce the dose of fentanyl, reduce the pharmacological load on the operated patient.Цель исследования: разработать методику потенцирования традиционной мультимодальной анестезии контактным лазерным воздействием на организм в области красного диапазона действия (650 нм) у пациентов с критической ишемией нижних конечностей (КИНК). Материалы и методы исследования. Мультимодальная анестезия в основной группе проведена с потенцированием современными лазерными технологиями у 35 пациентов [7 (20,0 %) женщин и 28 (80,0 %) мужчин] с КИНК и сопутствующими заболеваниями в возрасте от 70 до 94 лет. В качестве группы сравнения выбрана ретроспективная группа из 23 пациентов, которым была выполнена высокая ампутация нижних конечностей без потенцирования мультимодальной анестезии лазерным облучением крови. Мультимодальную анестезию потенцировали дополнительно сеансами квантовой гемотерапии. Сеансы осуществляли, используя полупроводниковый аппарат для контактного лазерного облучения крови LASPOT (КНР) пятого поколения в виде наручных часов с дополнительным воздействием на акупунктурные точки Ней-гуань, Тун-ли – меридиан сердца, связь с внутренним миром, Линдао – меридиан сердца, дорога духа. Первый сеанс пациентам проводили перед оперативным вмешательством, длительность 15 мин, второй – во время оперативного вмешательства, длительность 30 мин. Результаты исследования. Полученные данные о сдвигах показателей периферической гемодинамики на этапах оперативных вмешательств у пациентов обеих групп практически не демонстрировали существенных отличий от исходных значений, отражая адекватность степени анестезиологической защиты. У пациентов основной группы показатели центральной гемодинамики: достоверно увеличивался сердечный индекс (СИ) с 2,81 ± 0,49 до 3,15 ± 0,58 (р &lt; 0,05) л/мин∙м2, а общее периферическое сосудистое сопротивление (ОПСС) снижалось с 1587,5 ± 494,3 до 1492,7 ± 427,8 дин∙с∙см-5. У пациентов группы сравнения СИ увеличивался во время оперативного вмешательства с 2,83 ± 0,53 до 3,02 ± 0,35 л/мин∙м2, а в конце операции приходил к исходному уровню. Потенцирование мультимодальной анестезии современными лазерными технологиями у пациентов основной группы позволило снизить во время хирургических вмешательств среднюю дозу фентанила, которая составила 0,98 ± 0,12 мкг/кг/ч, в то время как у пациентов группы сравнения расход фентанила составлял 3,28 ± 0,18 мкг/кг/ч (при традиционной комбинированной общей анестезии расход фентанила в течение оперативного вмешательства в среднем составляет 5–12 мкг/кг/ч и более). Заключение. Метод потенцирования традиционной схемы общей комбинированной анестезии оптическим излучением красного диапазона действия (650 нм) позволяет достичь более выраженных эффектов контроля уровня гемодинамики, дает возможность снизить дозу фентанила, уменьшить фармакологическую нагрузку на оперируемого пациента

Production of D∗+(2010)D^{*+}(2010) mesons by high energy neutrinos from the Tevatron

Charged vector $D^{*+}(2010)$ meson production is studied in a high energy neutrino bubble chamber experiment with mean neutrino energy of 141 GeV. The $D^{*+}$ are produced in $(5.6 \pm 1.8)\%$ of the neutrino charged current interactions, indicating a steep increase of cross section with energy. The mean fractional hadronic energy of the $D^{*+}$ meson is $0.55 \pm 0.06$

Investigation of selected materials stability for future application in development of small fast modular reactors (SFMR)

Currently, there is growing demand for cheap and reliable electricity production. One possible solution could be the construction of small modular fast neutrons nuclear reactors, where the reactor core cooling fluid is a suitable liquid metal. Liquid tin has significant advantages over the other potential candidates but its usage as coolant is challenging for the confining materials ensuring the nuclear safety of the future reactors. Current paper presents an investigation of structural materials stability in liquid tin with measurement of the surface tension, based on “Wilhelmy plate” method. The results are related to stability of spring steel, iron, nickel and copper, used as dipping plates as well as oxygen/liquid tin interactions when melted tin is exposed to air. The reported custom apparatus in our previous studies, was improved and its measuring capability was enhanced in order to demonstrate reliable results at low cost. Theoretical analysis is provided in order to demonstrate the reliability of the presented approach. Main results include: (1) Determination of liquid tin surface tension in case of air oxygen/tin reaction in liquid surface; (2) Investigation of measuring plate degradation and calculation of solution rate constant in case of dipped a plate made by copper; (3) Determination of Butler’s equation parameters in case of surface oxygen/tin interactions