Knowledge management, innovation and big data: Implications for sustainability, policy making and competitiveness

This Special Issue of Sustainability devoted to the topic of “Knowledge Management, Innovation and Big Data: Implications for Sustainability, Policy Making and Competitiveness” attracted exponential attention of scholars, practitioners, and policy-makers from all over the world. Locating themselves at the expanding cross-section of the uses of sophisticated information and communication technology (ICT) and insights from social science and engineering, all papers included in this Special Issue contribute to the opening of new avenues of research in the field of innovation, knowledge management, and big data. By triggering a lively debate on diverse challenges that companies are exposed to today, this Special Issue offers an in-depth, informative, well-structured, comparative insight into the most salient developments shaping the corresponding fields of research and policymaking

Towards personalization in digital libraries through ontologies

In this paper we describe a browsing and searching personalization system for digital libraries based on the use of ontologies for describing the relationships between all the elements which take part in a digital library scenario of use. The main goal of this project is to help the users of a digital library to improve their experience of use by means of two complementary strategies: first, by maintaining a complete history record of his or her browsing and searching activities, which is part of a navigational user profile which includes preferences and all the aspects related to community involvement; and second, by reusing all the knowledge which has been extracted from previous usage from other users with similar profiles. This can be accomplished in terms of narrowing and focusing the search results and browsing options through the use of a recommendation system which organizes such results in the most appropriate manner, using ontologies and concepts drawn from the semantic web field. The complete integration of the experience of use of a digital library in the learning process is also pursued. Both the usage and information organization can be also exploited to extract useful knowledge from the way users interact with a digital library, knowledge that can be used to improve several design aspects of the library, ranging from internal organization aspects to human factors and user interfaces. Although this project is still on an early development stage, it is possible to identify all the desired functionalities and requirements that are necessary to fully integrate the use of a digital library in an e-learning environment

Taming under isoperimetry

In this article we propose a novel taming Langevin-based scheme called $\mathbf{sTULA}$ to sample from distributions with superlinearly growing log-gradient which also satisfy a Log-Sobolev inequality. We derive non-asymptotic convergence bounds in $KL$ and consequently total variation and Wasserstein-$2$ distance from the target measure. Non-asymptotic convergence guarantees are provided for the performance of the new algorithm as an optimizer. Finally, some theoretical results on isoperimertic inequalities for distributions with superlinearly growing gradients are provided. Key findings are a Log-Sobolev inequality with constant independent of the dimension, in the presence of a higher order regularization and a Poincare inequality with constant independent of temperature and dimension under a novel non-convex theoretical framework.Comment: 50 page

Synonymous dinucleotide usage: a codon-aware metric for quantifying dinucleotide representation in viruses

Distinct patterns of dinucleotide representation, such as CpG and UpA suppression, are characteristic of certain viral genomes. Recent research has uncovered vertebrate immune mechanisms that select against specific dinucleotides in targeted viruses. This evidence highlights the importance of systematically examining the dinucleotide composition of viral genomes. We have developed a novel metric, called synonymous dinucleotide usage (SDU), for quantifying dinucleotide representation in coding sequences. Our method compares the abundance of a given dinucleotide to the null hypothesis of equal synonymous codon usage in the sequence. We present a Python3 package, DinuQ, for calculating SDU and other relevant metrics. We have applied this method on two sets of invertebrate- and vertebrate-specific flaviviruses and rhabdoviruses. The SDU shows that the vertebrate viruses exhibit consistently greater under-representation of CpG dinucleotides in all three codon positions in both datasets. In comparison to existing metrics for dinucleotide quantification, the SDU allows for a statistical interpretation of its values by comparing it to a null expectation based on the codon table. Here we apply the method to viruses, but coding sequences of other living organisms can be analysed in the same way

Integrating descriptions of knowledge management learning activities into large ontological structures: A case study

Ontologies have been recognized as a fundamental infrastructure for advanced approaches to Knowledge Management (KM) automation, and the conceptual foundations for them have been discussed in some previous reports. Nonetheless, such conceptual structures should be properly integrated into existing ontological bases, for the practical purpose of providing the required support for the development of intelligent applications. Such applications should ideally integrate KM concepts into a framework of commonsense knowledge with clear computational semantics. In this paper, such an integration work is illustrated through a concrete case study, using the large OpenCyc knowledge base. Concretely, the main elements of the Holsapple & Joshi KM ontology and some existing work on e-learning ontologies are explicitly linked to OpenCyc definitions, providing a framework for the development of functionalities that use the built-in reasoning services of OpenCyc in KM ctivities. The integration can be used as the point of departure for the engineering of KM-oriented systems that account for a shared understanding of the discipline and rely on public semantics provided by one of the largest open knowledge bases available