Alien Registration- Lyle, John W. (Bangor, Penobscot County)

https://digitalmaine.com/alien_docs/11796/thumbnail.jp

Adaptive Multi-Vehicle Area Coverage Optimization System and Method

A mission planning system for determining an optimum use of a plurality of vehicles in searching a predefined geographic area (PGA). A discretizer subsystem may be used for sensing the capabilities of each vehicle to produce a point set defining a number of points within the PGA that the vehicles must traverse to completely search the PGA. A task allocator subsystem may determine an optimum division of the PGA into different subregions to be handled by specific ones of the vehicles, thus to minimize an overall time needed to search the PGA. A path optimizer subsystem may determine an optimum path through a particular vehicle\u27s assigned subregion to minimize the time needed for each specific vehicle to traverse its associated subregion

Intracranial lesions resulting from dental infection : Report of two cases

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/32580/1/0000709.pd

Spike-phase coupling patterns reveal laminar identity in primate cortex

The cortical column is one of the fundamental computational circuits in the brain. In order to understand the role neurons in different layers of this circuit play in cortical function it is necessary to identify the boundaries that separate the laminar compartments. While histological approaches can reveal ground truth they are not a practical means of identifying cortical layers in vivo. The gold standard for identifying laminar compartments in electrophysiological recordings is current-source density (CSD) analysis. However, laminar CSD analysis requires averaging across reliably evoked responses that target the input layer in cortex, which may be difficult to generate in less well-studied cortical regions. Further, the analysis can be susceptible to noise on individual channels resulting in errors in assigning laminar boundaries. Here, we have analyzed linear array recordings in multiple cortical areas in both the common marmoset and the rhesus macaque. We describe a pattern of laminar spike-field phase relationships that reliably identifies the transition between input and deep layers in cortical recordings from multiple cortical areas in two different non-human primate species. This measure corresponds well to estimates of the location of the input layer using CSDs, but does not require averaging or specific evoked activity. Laminar identity can be estimated rapidly with as little as a minute of ongoing data and is invariant to many experimental parameters. This method may serve to validate CSD measurements that might otherwise be unreliable or to estimate laminar boundaries when other methods are not practical

Crystallization and preliminary X-ray diffraction data for a purple acid phosphatase from sweet potato

Purple acid phosphatase from sweet potato is a homodimer of 110 kDa. Two forms of the enzyme have been characterized. One contains an Fe±Zn centre similar to that previously reported for red kidney bean purple acid phosphatase. Another isoform, the subject of this work, is the ®rst con®rmed example of an Fe±Mn-containing enzyme. Crystals of this protein have been grown from PEG 6000. They have unit-cell parameters a = b = 118.4, c = 287.4 A Ê and have the symmetry of space group P6522, with one dimer per asymmetric unit. Diffraction data collected using a conventional X-ray source from a cryocooled crystal extend to 2.90 A Ê resolution. The three-dimensional structure of the enzyme will provide insight into the coordination of this novel binuclear metal centre

Imaging Complex Structure in Shallow Seismic-reflection Data Using Prestack Depth Migration

Prestack depth migration (PSDM) analysis has the potential to significantly improve the accuracy of both shallow seismic reflection images and the measured velocity distributions. In a study designed to image faults in the Alvord Basin, Oregon, at depths from 25–1000 m, PSDM produced a detailed reflection image over the full target depth range. In contrast, poststack time migration produced significant migration artifacts in the upper 100 m that obscured reflection events and limited the structural interpretation in the shallow section. Additionally, an abrupt increase from ~2500 to \u3e3000 m/s in the PSDM velocity model constrained the interpretation of the transition from sedimentary basin fill to basement volcanic rocks. PSDM analysis revealed a complex extensional history with at least two distinct phases of basin growth and a midbasin basement high that forms the division between two major basin compartments

The Safety and Effect of Topically Applied Recombinant Basic Fibroblast Growth Factor on the Healing of Chronic Pressure Sores

The first randomized, blinded, placebo-controlled human trials of recombinant basic fibroblast growth factor (bFGF) for pressure sore treatment were performed. Three different concentrations of bFGF in five dosing schedules were tested for safety using hematology, serum chemistries, urinalysis, absorption, antibody formation, and signs of toxicity. Efficacy was evaluated by wound volumes, histology, and photography. No toxicity, significant serum absorption, or antibody formation occurred. In six of eight subgroups, there was a trend toward efficacy with bFGF treatment. When all subgroups were combined, comparison of the slopes of the regression curves of volume decrease over initial pressure sore volume demonstrated a greater healing effect for the bFGF-treated patients (p 70% wound closure (p < 0.05). Blinded observers were able to distinguish differences in visual wound improvement between bFGF and placebo groups. These data suggest that bFGF may be effective in the treatment of chronic wounds

Ohio Economic Insects and Related Anthropods

PDF pages: 3

Book reviews

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/45692/1/11336_2005_Article_BF02289006.pd

Systemic Effects of Arctic Pollutants in Beluga Whales Indicated by CYP1A1 Expression

Cytochrome P450 1A1 (CYP1A1) is induced by exposure to polycyclic aromatic hydrocarbons (PAHs) and planar halogenated aromatic hydrocarbons (PHAHs) such as non-ortho polychlorinated biphenyls (PCBs). In this study, we examined CYP1A1 protein expression immunohistochemically in multiple organs of beluga whales from two locations in the Arctic and from the St. Lawrence estuary. These beluga populations have some of the lowest (Arctic sites) and highest (St. Lawrence estuary) concentrations of PCBs in blubber of all cetaceans. Samples from these populations might be expected to have different contaminant-induced responses, reflecting their different exposure histories. The pattern and extent of CYP1A1 staining in whales from all three locations were similar to those seen in animal models in which CYP1A has been highly induced, indicating a high-level expression in these whales. CYP1A1 induction has been related to toxic effects of PHAHs or PAHs in some species. In St. Lawrence beluga, the high level of CYP1A1 expression coupled with high levels of contaminants (including CYP1A1 substrates, e.g., PAH procarcinogens potentially activated by CYP1A1) indicates that CYP1A1 could be involved in the development of neoplastic lesions seen in the St. Lawrence beluga population. The systemic high-level expression of CYP1A1 in Arctic beluga suggests that effects of PAHs or PHAHs may be expected in Arctic populations, as well. The high-level expression of CYP1A1 in the Arctic beluga suggests that this species is highly sensitive to CYP1A1 induction by aryl hydrocarbon receptor agonists