Nuclear modification factor in intermediate-energy heavy-ion collisions

The transverse momentum dependent nuclear modification factors (NMF), namely $R_{CP}$, is investigated for protons produced in Au + Au at 1$A$ GeV within the framework of the isospin-dependent quantum molecular dynamics (IQMD) model. It is found that the radial collective motion during the expansion stage affects the NMF at low transverse momentum a lot. By fitting the transverse mass spectra of protons with the distribution function from the Blast-Wave model, the magnitude of radial flow can be extracted. After removing the contribution from radial flow, the $R_{CP}$ can be regarded as a thermal one and is found to keep unitary at transverse momentum lower than 0.6 GeV/c and enhance at higher transverse momentum, which can be attributed to Cronin effect.Comment: 8 pages, 5 figures; aceepted by Physics Letters

Virtual Cellular Multi-period Formation under the Dynamic Environment

AbstractVirtual cellular manufacturing is an innovative way of production organization which both in the production of flexibility and efficient to meet today's rapid development of science and technology and replacement of products. The key process of the design of virtual cellular manufacturing system—cell formation is the focus of research. In order to meet the characteristics of small batch and dynamically changing market demand, this paper studies the problems of virtual cellular multi-period dynamic reconfiguration. A reconfigurable system programming model is developed. The model incorporates parameters of the problems of product dynamic demand, machine capacity, operation sequence, balanced workload, alternative routings and batch setting. The objective of mixed integer programming model is to minimize the total costs of operation, moving raw materials, inventory holding and process routes setup. Though a case study, demonstrates the feasibility and validity of the model in reality

Structure and morphology of X-ray selected AGN hosts at 1<z<3 in CANDELS-COSMOS field

We analyze morphologies of the host galaxies of 35 X-ray selected active galactic nucleus (AGNs) at $z\sim2$ in the Cosmic Evolution Survey (COSMOS) field using Hubble Space Telescope/WFC3 imaging taken from the Cosmic Assembly Near-infrared Deep Extragalactic Legacy Survey (CANDELS). We build a control sample of 350 galaxies in total, by selecting ten non-active galaxies drawn from the same field with the similar stellar mass and redshift for each AGN host. By performing two dimensional fitting with GALFIT on the surface brightness profile, we find that the distribution of S$\`e$rsic index (n) of AGN hosts does not show a statistical difference from that of the control sample. We measure the nonparametric morphological parameters (the asymmetry index A, the Gini coefficient G, the concentration index C and the M20 index) based on point source subtracted images. All the distributions of these morphological parameters of AGN hosts are consistent with those of the control sample. We finally investigate the fraction of distorted morphologies in both samples by visual classification. Only $\sim$15% of the AGN hosts have highly distorted morphologies, possibly due to a major merger or interaction. We find there is no significant difference in the distortion fractions between the AGN host sample and control sample. We conclude that the morphologies of X-ray selected AGN hosts are similar to those of nonactive galaxies and most AGN activity is not triggered by major merger.Comment: 5 pages, 3 figures, accepted for publication in The Astrophysical Journal Letter

Site selection and scale measurement of regional coal reserves: taking Jiangsu Province as an example

AbstractThe frequent coal shortages have widely aroused attention to the construction of coal reserve system, some coal reserve bases have been established in many provinces. But researches are few on site selection and scale measurement. With references to the researches on oil reserves, the paper first explored the influential factors on the site selection of regional coal reserves, taking Jiangsu Province as an example, three coal reserve bases should be built in Nanjing, Xuzhou and Lianyungang to ensure the coal supply. Then, learning from the researches on coal resources reserves and grain reserves, a general approach to calculate the scale of regional coal reserves was given, then, taking the direct-supply power plant in Jiangsu as an example, the scale of coal reserves were est imated with the fluctuation range of stock volatility (0, 0), (+1%, -1%), (+5%, -5%), (+10%, -10%), suggesting that the biggest dynamic reserves of 301,800 tons be moderate, with the fluctuation range of stock volatility (+5%, -5%). The research has important significance to promote the construction of regional coal reserve system

LHX1 as a potential biomarker regulates EMT induction and cellular behaviors in uterine corpus endometrial carcinoma

Objectives: To investigate the expression of LHX1 and its role as a biomarker in the diagnosis and prognosis of Uterine Corpus Endometrial Carcinoma (UCEC). Methods: The Cancer Genome Atlas (TCGA) database was used to detect the expression level of LHX1 in UCEC cells and tissues, and to find out the effect of LHX1 on prognosis. Co-expressed genes were then identified by Spearman correlation analysis, and the protein-protein interaction network was constructed using Cytoscape software. The R “clusterProfiler” package was used to conduct Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses. A series of in vitro experiments were performed to evaluate LHX1 expression and detect UCEC cell proliferation, invasion, and migration. Western blotting was used to determine the effect of LHX1 on expression levels of Epithelial-Mesenchymal Transition (EMT)-related proteins. Results: LHX1 was upregulated in UCEC tissues and correlated with poor overall survival and disease-specific survival outcomes. Functional enrichment analysis suggested that genes co-expressed with LHX1 were enriched in cell adhesion. The expression of LHX1 was positively correlated with the expression levels of genes related to EMT induction and invasion. LHX1 can enhance the proliferation, migration, and invasion activities of UCEC cells in vitro, and alter the expression levels of EMT-related proteins. Conclusion: LHX1 expression was highly upregulated in UCEC cells and tissues, which was correlated with the prognosis of patients with UCEC. LHX1 may regulate UCEC progression at least in part by modulating EMT induction