54 research outputs found
Robust Optical Data Encryption by Projection-Photoaligned Polymer-Stabilized-Liquid-Crystals
The emerging Internet of Things (IoTs) invokes increasing security demands
that require robust encryption or anti-counterfeiting technologies. Albeit
being acknowledged as efficacious solutions in processing elaborate graphical
information via multiple degrees of freedom, optical data encryption and
anti-counterfeiting techniques are typically inept in delivering satisfactory
performance without compromising the desired ease-of-processibility or
compatibility, thus leading to the exploration of novel materials and devices
that are competent. Here, a robust optical data encryption technique is
demonstrated utilizing polymer-stabilized-liquid-crystals (PSLCs) combined with
projection photoalignment and photopatterning methods. The PSLCs possess
implicit optical patterns encoded via photoalignment, as well as explicit
geometries produced via photopatterning. Furthermore, the PSLCs demonstrate
improved robustness against harsh chemical environments and thermal stability,
and can be directly deployed onto various rigid and flexible substrates. Based
on this, it is demonstrated that single PSLC is apt to carry intricate
information, or serve as exclusive watermark with both implicit features and
explicit geometries. Moreover, a novel, generalized design strategy is
developed, for the first time, to encode intricate and exclusive information
with enhanced security by spatially programming the photoalignment patterns of
a pair of cascade PSLCs, which further illustrates the promising capabilies of
PSLCs in optical data encryption and anti-counterfeiting
Heterologous expression of the Haynaldia villosa pattern-recognition receptor CERK1-V in wheat increases resistance to three fungal diseases
Wheat production is under continuous threat by various fungal pathogens. Identification of multiple-disease resistance genes may lead to effective disease control via the development of cultivars with broad-spectrum resistance. Plant Lysin-motif (LysM)-type pattern-recognition receptors, which elicit innate immunity by recognizing fungal pathogen associated molecular patterns such as chitin, are potential candidates for such resistance. In this study, we cloned a LysM receptor-like kinase gene, CERK1-V, from the diploid wheat relative Haynaldia villosa. CERK1-V expression was induced by chitin and Blumeria graminis f. sp. tritici, the causal agent of wheat powdery mildew. Heterologous overexpression of CERK1-V in wheat inhibited the development of three fungal pathogens, thereby increased resistance to powdery mildew, yellow rust, and Fusarium head blight. CERK1-V physically interacted with the wheat LysM protein TaCEBiPs. CERK1-V/TaCEBiPs interaction promoted chitin recognition and activated chitin signal transduction in wheat. Transgenic plants with excessively high CERK1-V expression showed high resistance but abnormal plant growth, whereas plants with moderate expression level showed adequate resistance level with no marked impairment of plant growth. In transgenic lines, RNA-seq showed that gene expression involved in plant innate immunity was activated. Expression of genes involved in photosynthesis, ER stress and multiple phytohormone pathways was also activated. Optimized expression of CERK1-V in wheat can confer disease resistance without compromising growth or defense fitness
A genome-wide association study in catfish reveals the presence of functional hubs of related genes within QTLs for columnaris disease resistance
Phase Behavior of PS-(PS-b-P2VP)(3) Miktoarm Star Copolymer
We synthesized polystyrene-[polystyrene-b-poly(2-vinylpyridine)](3) miktoarm star copolymer [PSL-(PSS-b-P2VP)(3)], where PSL and PSS are long and short PS chains, respectively, by the combination of anionic polymerization, atom transfer radical polymerization (ATRP), and click reaction. We changed the volume fraction of the PS block (f(PS)) and the chain asymmetry of the PS chain t = f(PS,L)/(f(PS, L) + f(PS,S)). Phase behavior of PS-(PS-b-P2VP)(3) was investigated by transmission electron microscopy (TEM) and small-angle X-ray scattering (SAXS). Inverted gyroids consisting of PS chains were formed at f(PS) = 0.64 and tau = 0.65, while asymmetric lamellae were observed at f(PS) = 0.81 and tau = 0.79. Because a long PS chain (PSL) and three short PSS-b-P2VP copolymer chains are linked at a single junction point, a huge configurational entropy penalty was expected, resulting in distorting the original phase boundaries observed for conventional AB diblock copolymer. PSS-b-P2VP chains are mainly located at the interface between PS and P2VP microdomains, whereas PSL chains fill the regions far from the interface, which causes a radial distribution to form interfacial curvature. Interestingly, the phase behavior was greatly affected by tau at a fixed f(PS). For instance, at a fixed f(PS) (0.64), an inverted gyroid structure was formed at tau = 0.65, while a lamellar structure was observed at tau = 0.46. With the decrease in tau (or the difference of molecular weight between PSL and PSS becomes smaller), the interfacial curvature is not expected because all PSS-b-P2VP chains have no need to be arranged in the same direction. The experimental results are consistent with the predictions based on self-consistent field theory (SCFT).11Nsciescopu
Comparison of the ED50 of prophylactic butorphanol in preventing morphine-induced pruritus with or without palonosetron: a prospective, double-blinded, randomized dose–response trial using an up-down sequential allocation method
AbstractBackground Butorphanol has been used to reduce the incidence and severity of neuraxial morphine-induced pruritus. Palonosetron is a commonly used antiemetic for the prevention of postoperative nausea and vomiting. The aim of our study was to compare the effective dose in 50% of subjects (ED50) of intravenous butorphanol infusion with or without a single intravenous bolus of palonosetron for preventing pruritus induced by epidural administration of morphine.Methods A total of 120 parturients were randomly assigned to receive an intravenous bolus injection of palonosetron plus continuous infusion of butorphanol (Group P + B) or an intravenous bolus of saline plus continuous infusion of butorphanol (Group B) after epidural administration of morphine. The antipruritic effect was graded as satisfactory (numerical rating scale (NRS) of pruritus ≤3) or unsatisfactory (NRS >3) within 48 h after morphine treatment. The first patient in each group received butorphanol infusion at a rate of 4 µg/kg/h. The infusion dose for each subsequent patient in the corresponding group was increased by 0.2 µg/kg/h after an unsatisfactory response or decreased by 0.2 µg/kg/h after a satisfactory response. The ED50 was calculated for each group and compared using up-down sequential analysis.Results The ED50 (mean [95% confidence interval (CI)]) of the dose of intravenous butorphanol infusion for preventing moderate to severe pruritus was lower in Group P + B (3.29 µg/kg/min [3.25–3.34 µg/kg/min]) than in Group B (3.57 µg/kg/min [3.47–3.67 µg/kg/min]) (p < 0.05).Conclusions Under the conditions of the present study, a prophylactic use of 0.25 mg palonosetron reduced the ED50 of prophylactic infusion of butorphanol by approximately 8% to achieve a satisfactory antipruritic effect after epidural morphine for post-caesarean analgesia
Preliminary investigation of the degradation mechanism of o, m and p-cresol using sludge-derived carbon nanosheets by catalytic oxidation based on quantum chemistry
Advanced oxidation technology is widely used to oxidize organic compounds in the liquid phase by OH conventionally. Here, we prepared a sludge-derived carbon nanosheets, which was applied in the catalytic wet air oxidation (CWAO), catalytic wet peroxide oxidation (CWPO) and catalytic wet ozone oxidation (CWOO) systems. Because of its abundant oxygen-containing functional groups, the catalytic activity of nanosheets was much higher than some conventional catalysts. It was found that the first-order reaction model did not have similar characteristics as expected. Combining with molecular descriptors calculated by the DFT method and PLS analysis, we try to explain this phenomenon for the first time and proposed possible mechanisms for the three advanced oxidation technologies
Characterization of sucrose nonfermenting-1-related protein kinase 2 (SnRK2) gene family in Haynaldia villosa demonstrated SnRK2.9-V enhances drought and salt stress tolerance of common wheat
Abstract Background The sucrose nonfermenting-1-related protein kinase 2 (SnRK2) plays a crucial role in responses to diverse biotic/abiotic stresses. Currently, there are reports on these genes in Haynaldia villosa, a diploid wild relative of wheat. Results To understand the evolution of SnRK2-V family genes and their roles in various stress conditions, we performed genome-wide identification of the SnRK2-V gene family in H. villosa. Ten SnRK2-V genes were identified and characterized for their structures, functions and spatial expressions. Analysis of gene exon/intron structure further revealed the presence of evolutionary paths and replication events of SnRK2-V gene family in the H. villosa. In addition, the features of gene structure, the chromosomal location, subcellular localization of the gene family were investigated and the phylogenetic relationship were determined using computational approaches. Analysis of cis-regulatory elements of SnRK2-V gene members revealed their close correlation with different phytohormone signals. The expression profiling revealed that ten SnRK2-V genes expressed at least one tissue (leave, stem, root, or grain), or in response to at least one of the biotic (stripe rust or powdery mildew) or abiotic (drought or salt) stresses. Moreover, SnRK2.9-V was up-regulated in H. villosa under the drought and salt stress and overexpressing of SnRK2.9-V in wheat enhanced drought and salt tolerances via enhancing the genes expression of antioxidant enzymes, revealing a potential value of SnRK2.9-V in wheat improvement for salt tolerance. Conclusion Our present study provides a basic genome-wide overview of SnRK2-V genes in H. villosa and demonstrates the potential use of SnRK2.9-V in enhancing the drought and salt tolerances in common wheat
The phenotypic plasticity of developmental modules
Abstract Background Organisms develop and evolve in a modular fashion, but how individual modules interact with the environment remains poorly understood. Phenotypically plastic traits are often under selection, and studies are needed to address how traits respond to the environment in a modular fashion. In this study, tissue-specific plasticity of melanic spots was examined in the large milkweed bug, Oncopeltus fasciatus. Results Although the size of the abdominal melanic bands varied according to rearing temperatures, wing melanic bands were more robust. To explore the regulation of abdominal pigmentation plasticity, candidate genes involved in abdominal melanic spot patterning and biosynthesis of melanin were analyzed. While the knockdown of dopa decarboxylase (Ddc) led to lighter pigmentation in both the wings and the abdomen, the shape of the melanic elements remained unaffected. Although the knockdown of Abdominal-B (Abd-B) partially phenocopied the low-temperature phenotype, the abdominal bands were still sensitive to temperature shifts. These observations suggest that regulators downstream of Abd-B but upstream of DDC are responsible for the temperature response of the abdomen. Ablation of wings led to the regeneration of a smaller wing with reduced melanic bands that were shifted proximally. In addition, the knockdown of the Wnt signaling nuclear effector genes, armadillo 1 and armadillo 2, altered both the melanic bands and the wing shape. Thus, the pleiotropic effects of Wnt signaling may constrain the amount of plasticity in wing melanic bands. Conclusions We propose that when traits are regulated by distinct pre-patterning mechanisms, they can respond to the environment in a modular fashion, whereas when the environment impacts developmental regulators that are shared between different modules, phenotypic plasticity can manifest as a developmentally integrated system
High-Density Packing of Spherical Microdomains from A(AB<sub>3</sub>)<sub>3</sub> Dendron-like Miktoarm Star Copolymer
An
A(AB3)3 dendron-like miktoarm
star copolymer
consisting of polystyrene (PS, A) and poly(2-vinylpyridine) (P2VP,
B) was synthesized using a series of anionic polymerization, atom-transfer
radical polymerization (ATRP), and click reaction. The morphology
of A(AB3)3 changed greatly depending on the
volume fraction of A and the chain asymmetry. Interestingly, a body-centered
cubic spherical phase was found even at fA = 0.51 because the chain architecture of A(AB3)3 stabilizes the large interfacial curvature toward A domains. On
the other hand, when the length difference between the end and middle
A blocks decreased, a hexagonally packed cylindrical phase was formed
at fA = 0.50. This is attributed to the
fact that the middle A chains are arranged in a more relaxed way,
resulting in a milder interfacial curvature toward A domains. The
experimental observations are well-consistent with the predictions
based on self-consistent-field theory
MOESM1 of The phenotypic plasticity of developmental modules
Additional file 1. Armadillo 1 and armadillo 2 sequences cloned for silencing
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