2,611 research outputs found
Atrial high-rate episodes: prevalence, stroke risk, implications for management, and clinical gaps in evidence
Self-terminating atrial arrhythmias are commonly detected on continuous rhythm monitoring, e.g. by pacemakers or defibrillators. It is unclear whether the presence of these arrhythmias has therapeutic consequences. We sought to summarize evidence on the prevalence of atrial high-rate episodes (AHREs) and their impact on risk of stroke. We performed a comprehensive, tabulated review of published literature on the prevalence of AHRE. In patients with AHRE, but without atrial fibrillation (AF), we reviewed the stroke risk and the potential risk/benefit of oral anticoagulation. Atrial high-rate episodes are found in 10-30% of AF-free patients. Presence of AHRE slightly increases stroke risk (0.8% to 1%/year) compared with patients without AHRE. Atrial high-rate episode of longer duration (e.g. those >24 h) could be associated with a higher stroke risk. Oral anticoagulation has the potential to reduce stroke risk in patients with AHRE but is associated with a rate of major bleeding of 2%/year. Oral anticoagulation is not effective in patients with heart failure or survivors of a stroke without AF. It remains unclear whether anticoagulation is effective and safe in patients with AHRE. Atrial high-rate episodes are common and confer a slight increase in stroke risk. There is true equipoise on the best way to reduce stroke risk in patients with AHRE. Two ongoing trials (NOAH-AFNET 6 and ARTESiA) will provide much-needed information on the effectiveness and safety of oral anticoagulation using non-vitamin K antagonist oral anticoagulants in patients with AHRE.info:eu-repo/semantics/publishedVersio
Van der Waals Density Functional for General Geometries
A scheme within density functional theory is proposed that provides a
practical way to generalize to unrestricted geometries the method applied with
some success to layered geometries [H. Rydberg, et al., Phys. Rev. Lett. 91,
126402 (2003)]. It includes van der Waals forces in a seamless fashion. By
expansion to second order in a carefully chosen quantity contained in the long
range part of the correlation functional, the nonlocal correlations are
expressed in terms of a density-density interaction formula. It contains a
relatively simple parametrized kernel, with parameters determined by the local
density and its gradient. The proposed functional is applied to rare gas and
benzene dimers, where it is shown to give a realistic description.Comment: 4 pages, 4 figure
Electron self-energy in A3C60 (A=K, Rb): Effects of t1u plasmon in GW approximation
The electron self-energy of the t1u states in A3C60 (A=K, Rb) is calculated
using the so-called GW approximation. The calculation is performed within a
model which considers the t1u charge carrier plasmon at 0.5 eV and takes into
account scattering of the electrons within the t1u band. A moderate reduction
(35 %) of the t1u band width is obtained.Comment: 4 pages, revtex, 1 figure more information at
http://www.mpi-stuttgart.mpg.de/dokumente/andersen/fullerene
Nickel Mixing in the Outer Layers of SN 1987A
Supernova 1987A remains the most well-observed and well-studied supernova to
date. Observations produced excellent broad-band photometric and spectroscopic
coverage over a wide wavelength range at all epochs. Here, we focus on the very
early spectroscopic observations. Only recently have numerical models been of
sufficient detail to accurately explain the observed spectra. In SN 1987A, good
agreement has been found between observed and synthetic spectra for day one,
but by day four, the predicted Balmer lines become much weaker than the
observed lines. We present the results of work based on a
radiation-hydrodynamic model by Blinnikov and collaborators. Synthetic non-LTE
spectra generated from this model by the general radiation transfer code
PHOENIX strongly support the theory that significant mixing of nickel into the
outer envelope is required to maintain strong Balmer lines. Preliminary results
suggest a lower limit to the average nickel mass of 1.0 \times 10^{-5} solar
masses is required above 5000 \kmps by day four. PHOENIX models thus have the
potential to be a sensitive probe for nickel mixing in the outer layers of a
supernova.Comment: 16 pages, 7 figures, ApJ, v556 2001 (in press
Charge carrier interaction with a purely electronic collective mode: Plasmarons and the infrared response of elemental bismuth
We present a detailed optical study of single crystal bismuth using infrared
reflectivity and ellipsometry. Colossal changes in the plasmon frequency are
observed as a function of temperature due to charge transfer between hole and
electron Fermi pockets. In the optical conductivity, an anomalous temperature
dependent mid-infrared absorption feature is observed. An extended Drude model
analysis reveals that it can be connected to a sharp upturn in the scattering
rate, the frequency of which exactly tracks the temperature dependent plasmon
frequency. We interpret this absorption and increased scattering as the first
direct optical evidence for a charge carrier interaction with a collective mode
of purely electronic origin; here electron-plasmon scattering. The observation
of a \emph{plasmaron} as such is made possible only by the unique coincidence
of various energy scales and exceptional properties of semi-metal bismuth.Comment: 4 pages, 4 figure
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