144 research outputs found

    “HOW SCARED ARE YOU?” Mapping the Threat Environment of San Diego’s Elected Officials

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    Democracy cannot function without individuals stepping up to serve as representatives of their community. The presence and growth of threats and harassment directed towards elected representatives poses a direct risk to our democracy, weakening community cohesion and our ability to address collective challenges. While our research found threats and harassment to be present across political parties, it identified women as far more likely to be on the receiving end both in terms of quantity and severity. If under-represented groups are pushed out of the processes of debate and decision-making, solutions will not be oriented around the diversity of our society. Without clear data on the scale of the problem, the rise in threats and ad hominem attacks are too easily discounted by public officials, the media and the public at large. Possible consequences range from an increased potential for physical violence and the resignation from public life of elected officials. The research outlined in this report helps to expose the scale of threats and harassment, while in turn providing recommendations from those directly impacted, concerned community members and scholars on how to reinforce safe and non-threatening local governance. While several studies have shown that cities, counties and states across the country are experiencing an increased level of hostility towards elected officials, very few geographically designated areas are measuring incidents in any structured way. The research outlined in this report aims to set a clear baseline on the extent of aggressive behavior towards nearly all categories of elected office in San Diego County. Our research looked at all County School Boards, Community College Boards, City Councils, Mayors, and the County Board of Supervisors. Using a mixed methods approach that included surveys, interviews, a traditional media review and social media review, our team was able to get a clear picture of the problem both objectively and subjectively. Our findings confirm that the rise in threats and harassments targeting elected officials identified in national studies is also occurring at the local level in San Diego County. This rise in hostile threatening behavior towards elected officials is having a measurable impact on a) the ability of elected office holders to effectively participate in the public policy process; b) the likelihood of elected officials seeking to encourage others to enter public life or remain in public life themselves; and c) the psychological and physical health of office holders and their families. The vitriol we are seeing risks significantly and negatively impact the vitality of local democracy, civic engagement and effective policy making on across the policy spectrum.https://digital.sandiego.edu/ipj-research/1068/thumbnail.jp

    One Pager - “How Scared Are You?” Mapping the Threat Environment of San Diego’s Elected Officials

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    This one pager includes data summary points from survey sent to San Diego County elected officials. Targeted threats and the perpetration of physical violence against elected officials have been increasing steadily around the world. Democracy cannot function without individuals serving in elected governance. The presence and growth of threats and harassment undermines community cohesion, further undermining our ability to address our collective challenges.https://digital.sandiego.edu/ipj-research/1067/thumbnail.jp

    Keynote Address at the Institute for Civil Civic Engagement’s Eighth Annual Conference on Restoring Civility to Civic Dialogue: Restoring Respect

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    Keynote Address at the Institute for Civil Civic Engagement’s Eighth Annual Conference on Restoring Civility to Civic Dialogue: Restoring Respec

    The Concept and Analytical Investigation of CO2 and Steam Co-Electrolysis for Resource Utilization in Space Exploration

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    CO2 acquisition and utilization technologies will have a vital role in designing sustainable and affordable life support and in situ fuel production architectures for human and robotic exploration of Moon and Mars. For long-term human exploration to be practical, reliable technologies have to be implemented to capture the metabolic CO2 from the cabin air and chemically reduce it to recover oxygen. Technologies that enable the in situ capture and conversion of atmospheric CO2 to fuel are essential for a viable human mission to Mars. This paper describes the concept and mathematical analysis of a closed-loop life support system based on combined electrolysis of CO2 and steam (co-electrolysis). Products of the coelectrolysis process include oxygen and syngas (CO and H2) that are suitable for life support and synthetic fuel production, respectively. The model was developed based on the performance of a co-electrolysis system developed at Idaho National Laboratory (INL). Individual and combined process models of the co-electrolysis and Sabatier, Bosch, Boudouard, and hydrogenation reactions are discussed and their performance analyses in terms of oxygen production and CO2 utilization are presented

    Mathematical Analysis of a Novel Approach to Maximize Waste Recovery in a Life Support System

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    NASA has been evaluating closed-loop atmosphere revitalization architectures carbon dioxide, CO2, reduction technologies. The CO2 and steam, H2O, co-electrolysis process is another option that NASA has investigated. Utilizing recent advances in the fuel cell technology sector, the Idaho National Laboratory, INL, has developed a CO2 and H2O co-electrolysis process to produce oxygen and syngas (carbon monoxide, CO and hydrogen, H2 mixture) for terrestrial (energy production) application. The technology is a combined process that involves steam electrolysis, CO2 electrolysis, and the reverse water gas shift (RWGS) reaction. Two process models were developed to evaluate novel approaches for waster recovery in a life support system. The first is a model INL co-electrolysis process combined with a methanol production process. The second is the INL co-electrolysis process combined with a pressure swing adsorption (PSA) process. For both processes, the overall power increases as the syngas ratio, H2/CO, increases because more water is needed to produce more hydrogen at a set CO2 incoming flow rate. The power for the methanol cases is less than the PSA because heat is available from the methanol reactor to preheat the water and carbon dioxide entering the co-electrolysis process

    Shear Strength Measurement Benchmarking Tests for K Basin Sludge Simulants

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    Equipment development and demonstration testing for sludge retrieval is being conducted by the K Basin Sludge Treatment Project (STP) at the MASF (Maintenance and Storage Facility) using sludge simulants. In testing performed at the Pacific Northwest National Laboratory (under contract with the CH2M Hill Plateau Remediation Company), the performance of the Geovane instrument was successfully benchmarked against the M5 Haake rheometer using a series of simulants with shear strengths (τ) ranging from about 700 to 22,000 Pa (shaft corrected). Operating steps for obtaining consistent shear strength measurements with the Geovane instrument during the benchmark testing were refined and documented

    Learning to Detect Touches on Cluttered Tables

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    We present a novel self-contained camera-projector tabletop system with a lamp form-factor that brings digital intelligence to our tables. We propose a real-time, on-device, learning-based touch detection algorithm that makes any tabletop interactive. The top-down configuration and learning-based algorithm makes our method robust to the presence of clutter, a main limitation of existing camera-projector tabletop systems. Our research prototype enables a set of experiences that combine hand interactions and objects present on the table. A video can be found at https://youtu.be/hElC_c25Fg8

    TUFT1 interacts with RABGAP1 and regulates mTORC1 signaling

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    The mammalian target of rapamycin (mTOR) pathway is commonly activated in human cancers. The activity of mTOR complex 1 (mTORC1) signaling is supported by the intracellular positioning of cellular compartments and vesicle trafficking, regulated by Rab GTPases. Here we showed that tuftelin 1 (TUFT1) was involved in the activation of mTORC1 through modulating the Rab GTPase-regulated process. TUFT1 promoted tumor growth and metastasis. Consistently, the expression of TUFT1 correlated with poor prognosis in lung, breast and gastric cancers. Mechanistically, TUFT1 physically interacted with RABGAP1, thereby modulating intracellular lysosomal positioning and vesicular trafficking, and promoted mTORC1 signaling. In addition, expression of TUFT1 predicted sensitivity to perifosine, an alkylphospholipid that alters the composition of lipid rafts. Perifosine treatment altered the positioning and trafficking of cellular compartments to inhibit mTORC1. Our observations indicate that TUFT1 is a key regulator of the mTORC1 pathway and suggest that it is a promising therapeutic target or a biomarker for tumor progression.UTokyo FOCUS Articles掲載「がんの増殖・転移を促進する新規因子の同定 小胞輸送を標的とする新しいがん治療戦略への可能性」 https://www.u-tokyo.ac.jp/focus/ja/articles/z0508_00119.htmlUTokyo FOCUS Articles "Possible target for future cancer treatment : Deregulation of system to move molecules in the cell may promote tumor growth, metastasis" https://www.u-tokyo.ac.jp/focus/en/articles/z0508_00120.htm

    Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

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    This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing molecular features of squamous cell carcinomas (SCCs) from five sites associated with smokin
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