927 research outputs found
Dynamics of threads and polymers in turbulence: power-law distributions and synchronization
We study the behavior of threads and polymers in a turbulent flow. These
objects have finite spatial extension, so the flow along them differs slightly.
The corresponding drag forces produce a finite average stretching and the
thread is stretched most of the time. Nevertheless, the probability of
shrinking fluctuations is significant and is known to decay only as a
power-law. We show that the exponent of the power law is a universal number
independent of the statistics of the flow. For polymers the coil-stretch
transition exists: the flow must have a sufficiently large Lyapunov exponent to
overcome the elastic resistance and stretch the polymer from the coiled state
it takes otherwise. The probability of shrinking from the stretched state above
the transition again obeys a power law but with a non-universal exponent. We
show that well above the transition the exponent becomes universal and derive
the corresponding expression. Furthermore, we demonstrate synchronization: the
end-to-end distances of threads or polymers above the transition are
synchronized by the flow and become identical. Thus, the transition from
Newtonian to non-Newtonian behavior in dilute polymer solutions can be seen as
an ordering transition.Comment: 13 pages, version accepted to Journal of Statistical Mechanic
Linear Stochastic Models of Nonlinear Dynamical Systems
We investigate in this work the validity of linear stochastic models for
nonlinear dynamical systems. We exploit as our basic tool a previously proposed
Rayleigh-Ritz approximation for the effective action of nonlinear dynamical
systems started from random initial conditions. The present paper discusses
only the case where the PDF-Ansatz employed in the variational calculation is
``Markovian'', i.e. is determined completely by the present values of the
moment-averages. In this case we show that the Rayleigh-Ritz effective action
of the complete set of moment-functions that are employed in the closure has a
quadratic part which is always formally an Onsager-Machlup action. Thus,
subject to satisfaction of the requisite realizability conditions on the noise
covariance, a linear Langevin model will exist which reproduces exactly the
joint 2-time correlations of the moment-functions. We compare our method with
the closely related formalism of principal oscillation patterns (POP), which,
in the approach of C. Penland, is a method to derive such a linear Langevin
model empirically from time-series data for the moment-functions. The
predictive capability of the POP analysis, compared with the Rayleigh-Ritz
result, is limited to the regime of small fluctuations around the most probable
future pattern. Finally, we shall discuss a thermodynamics of statistical
moments which should hold for all dynamical systems with stable invariant
probability measures and which follows within the Rayleigh-Ritz formalism.Comment: 36 pages, 5 figures, seceq.sty for sequential numbering of equations
by sectio
The sintering, sintered microstructure and mechanical properties of Ti-Fe-Si Alloys
A systematic study has been conducted of the sintering, sintered microstructure and tensile properties of a range of lower cost Ti-Fe-Si alloys, including Ti-3Fe-(0-4)Si, Ti-(3-6)Fe-0.5Si, and Ti-(3-6)Fe-1Si (in wt pct throughout). Small additions of Si (≤1 pct) noticeably improve the as-sintered tensile properties of Ti-3Fe alloy, including the ductility, with fine titanium silicides (TiSi) being dispersed in both the α and β phases. Conversely, additions of >1 pct Si produce coarse and/or networked TiSi silicides along the grain boundaries leading to predominantly intergranular fracture and, hence, poor ductility, although the tensile strength continues to increase because of the reinforcement by TiSi. Increasing the Fe content in the Ti-xFe-0.5/ 1.0Si alloys above 3 pct markedly increases the average grain size and changes the morphology of the α-phase phase to much thinner and more acicular laths. Consequently, the ductility drops t
Associations of NINJ2 sequence variants with incident ischemic stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) consortium
Background<p></p>
Stroke, the leading neurologic cause of death and disability, has a substantial genetic component. We previously conducted a genome-wide association study (GWAS) in four prospective studies from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium and demonstrated that sequence variants near the NINJ2 gene are associated with incident ischemic stroke. Here, we sought to fine-map functional variants in the region and evaluate the contribution of rare variants to ischemic stroke risk.<p></p>
Methods and Results<p></p>
We sequenced 196 kb around NINJ2 on chromosome 12p13 among 3,986 European ancestry participants, including 475 ischemic stroke cases, from the Atherosclerosis Risk in Communities Study, Cardiovascular Health Study, and Framingham Heart Study. Meta-analyses of single-variant tests for 425 common variants (minor allele frequency [MAF] ≥ 1%) confirmed the original GWAS results and identified an independent intronic variant, rs34166160 (MAF = 0.012), most significantly associated with incident ischemic stroke (HR = 1.80, p = 0.0003). Aggregating 278 putatively-functional variants with MAF≤ 1% using count statistics, we observed a nominally statistically significant association, with the burden of rare NINJ2 variants contributing to decreased ischemic stroke incidence (HR = 0.81; p = 0.026).<p></p>
Conclusion<p></p>
Common and rare variants in the NINJ2 region were nominally associated with incident ischemic stroke among a subset of CHARGE participants. Allelic heterogeneity at this locus, caused by multiple rare, low frequency, and common variants with disparate effects on risk, may explain the difficulties in replicating the original GWAS results. Additional studies that take into account the complex allelic architecture at this locus are needed to confirm these findings
Pulmonary Effects of Indoor- and Outdoor-Generated Particles in Children with Asthma
Most particulate matter (PM) health effects studies use outdoor (ambient) PM as a surrogate for personal exposure. However, people spend most of their time indoors exposed to a combination of indoor-generated particles and ambient particles that have infiltrated. Thus, it is important to investigate the differential health effects of indoor- and ambient-generated particles. We combined our recently adapted recursive model and a predictive model for estimating infiltration efficiency to separate personal exposure (E) to PM(2.5) (PM with aerodynamic diameter ≤2.5 μm) into its indoor-generated (E(ig)) and ambient-generated (E(ag)) components for 19 children with asthma. We then compared E(ig) and E(ag) to changes in exhaled nitric oxide (eNO), a marker of airway inflammation. Based on the recursive model with a sample size of eight children, E(ag) was marginally associated with increases in eNO [5.6 ppb per 10-μg/m(3) increase in PM(2.5); 95% confidence interval (CI), −0.6 to 11.9; p = 0.08]. E(ig) was not associated with eNO (−0.19 ppb change per 10μg/m(3)). Our predictive model allowed us to estimate E(ag) and E(ig) for all 19 children. For those combined estimates, only E(ag) was significantly associated with an increase in eNO (E(ag): 5.0 ppb per 10-μg/m(3) increase in PM(2.5;) 95% CI, 0.3 to 9.7; p = 0.04; E(ig): 3.3 ppb per 10-μg/m(3) increase in PM(2.5); 95% CI, −1.1 to 7.7; p = 0.15). Effects were seen only in children who were not using corticosteroid therapy. We conclude that the ambient-generated component of PM(2.5) exposure is consistently associated with increases in eNO and the indoor-generated component is less strongly associated with eNO
Neck pain and anxiety do not always go together
Chronic pain and psychosocial distress are generally thought to be associated in chronic musculoskeletal disorders such as non-specific neck pain. However, it is unclear whether a raised level of anxiety is necessarily a feature of longstanding, intense pain amongst patient and general population sub-groups. In a cohort of 70 self-selected female, non-specific neck pain sufferers, we observed relatively high levels of self-reported pain of 4.46 (measured on the 11 point numerical pain rating scale (NRS-101)) and a longstanding duration of symptoms (156 days/year). However, the mean anxiety scores observed (5.49), fell well below the clinically relevant threshold of 21 required by the Beck Anxiety Inventory. The cohort was stratified to further distinguish individuals with higher pain intensity (NRS>6) and longer symptom duration (>90 days). Although a highly statistically significant difference (p = 0.000) was subsequently observed with respect to pain intensity, in the resulting sub-groups, none such a difference was noted with respect to anxiety levels. Our results indicate that chronic, intense pain and anxiety do not always appear to be related. Explanations for these findings may include that anxiety is not triggered in socially functional individuals, that individual coping strategies have come into play or in some instances that a psychological disorder like alexithymia could be a confounder. More studies are needed to clarify the specific role of anxiety in chronic non-specific musculoskeletal pain before general evidence-driven clinical extrapolations can be made
Acoustic characteristics of a ported shroud turbocompressor operating at design conditions
[EN] In this article, the acoustic characterisation of a turbocharger compressor with ported shroud design is carried out through the numerical simulation of the system operating under design conditions of maximum isentropic efficiency. While ported shroud compressors have been proposed as a way to control the flow near unstable conditions in order to obtain a more stable operation and enhance deep surge margin, it is often assumed that the behaviour under stable design conditions is characterised by a smooth, non-detached flow that matches an equivalent standard compressor. Furthermore, research is scarce regarding the acoustic effects of the ported shroud addition, especially under the design conditions. To analyse the flow field evolution and its relation with the noise generation, spectral signatures using statistical and scale-resolving turbulence modelling methods are obtained after successfully validating the performance and acoustic predictions of the numerical model with experimental measurements. Propagation of the frequency content through the ducts has been estimated with the aid of pressure decomposition methods to enhance the content coming from the compressor. Expected acoustic phenomena such as `buzz-saw¿ tones, blade passing peaks and broadband noise are correctly identified in the modelled spectrum. Analysis of the flow behaviour in the ported shroud shows rotating structures through the slot that may impact the acoustic and vibration response. Further inspection of the pressure field through modal decomposition confirms the influence of the ported shroud cavity in noise generation and propagation, especially at lower frequencies, suggesting that further research should be carried out on the impact these flow enhancement solutions have on the noise emission of the turbocharger.The project was sponsored and supported by BorgWarner Turbo Systems and the Regional Growth Fund (RGF Grant Award 01.09.07.01/1789C). The authors would like to thank BorgWarner Turbo Systems for permission to publish the results presented in this article. The support of the HPC group at the University of Huddersfield is gratefully acknowledged.Sharma, S.; Broatch, A.; Garcia Tiscar, J.; Allport, JM.; Nickson, AK. (2020). Acoustic characteristics of a ported shroud turbocompressor operating at design conditions. International Journal of Engine Research. 21(8):1454-1468. https://doi.org/10.1177/1468087418814635S14541468218Sundström, E., Semlitsch, B., & Mihăescu, M. (2017). Generation Mechanisms of Rotating Stall and Surge in Centrifugal Compressors. Flow, Turbulence and Combustion, 100(3), 705-719. doi:10.1007/s10494-017-9877-zGonzalez, A., Ferrer, M., de Diego, M., Piñero, G., & Garcia-Bonito, J. . (2003). Sound quality of low-frequency and car engine noises after active noise control. Journal of Sound and Vibration, 265(3), 663-679. doi:10.1016/s0022-460x(02)01462-1Brizon, C. J. da S., & Bauzer Medeiros, E. (2012). Combining subjective and objective assessments to improve acoustic comfort evaluation of motor cars. Applied Acoustics, 73(9), 913-920. doi:10.1016/j.apacoust.2012.03.013Teng, C., & Homco, S. (2009). Investigation of Compressor Whoosh Noise in Automotive Turbochargers. SAE International Journal of Passenger Cars - Mechanical Systems, 2(1), 1345-1351. doi:10.4271/2009-01-2053Figurella, N., Dehner, R., Selamet, A., Tallio, K., Miazgowicz, K., & Wade, R. (2014). Noise at the mid to high flow range of a turbocharger compressor. Noise Control Engineering Journal, 62(5), 306-312. doi:10.3397/1/376229Torregrosa, A. J., Broatch, A., Margot, X., García-Tíscar, J., Narvekar, Y., & Cheung, R. (2017). Local flow measurements in a turbocharger compressor inlet. Experimental Thermal and Fluid Science, 88, 542-553. doi:10.1016/j.expthermflusci.2017.07.007Broatch, A., Galindo, J., Navarro, R., García-Tíscar, J., Daglish, A., & Sharma, R. K. (2015). Simulations and measurements of automotive turbocharger compressor whoosh noise. Engineering Applications of Computational Fluid Mechanics, 9(1), 12-20. doi:10.1080/19942060.2015.1004788Raitor, T., & Neise, W. (2008). Sound generation in centrifugal compressors. Journal of Sound and Vibration, 314(3-5), 738-756. doi:10.1016/j.jsv.2008.01.034Galindo, J., Tiseira, A., Navarro, R., & López, M. A. (2015). Influence of tip clearance on flow behavior and noise generation of centrifugal compressors in near-surge conditions. International Journal of Heat and Fluid Flow, 52, 129-139. doi:10.1016/j.ijheatfluidflow.2014.12.004Broatch, A., Galindo, J., Navarro, R., & García-Tíscar, J. (2014). Methodology for experimental validation of a CFD model for predicting noise generation in centrifugal compressors. International Journal of Heat and Fluid Flow, 50, 134-144. doi:10.1016/j.ijheatfluidflow.2014.06.006Semlitsch, B., & Mihăescu, M. (2016). Flow phenomena leading to surge in a centrifugal compressor. Energy, 103, 572-587. doi:10.1016/j.energy.2016.03.032Sundström, E., Semlitsch, B., & Mihăescu, M. (2018). Acoustic signature of flow instabilities in radial compressors. Journal of Sound and Vibration, 434, 221-236. doi:10.1016/j.jsv.2018.07.040Torregrosa, A. J., Broatch, A., Margot, X., & García-Tíscar, J. (2016). Experimental methodology for turbocompressor in-duct noise evaluation based on beamforming wave decomposition. Journal of Sound and Vibration, 376, 60-71. doi:10.1016/j.jsv.2016.04.035Nicoud, F., & Ducros, F. (1999). Flow, Turbulence and Combustion, 62(3), 183-200. doi:10.1023/a:1009995426001Chow, P., Cross, M., & Pericleous, K. (1996). A natural extension of the conventional finite volume method into polygonal unstructured meshes for CFD application. Applied Mathematical Modelling, 20(2), 170-183. doi:10.1016/0307-904x(95)00156-eKaji, S., & Okazaki, T. (1970). Generation of sound by rotor-stator interaction. Journal of Sound and Vibration, 13(3), 281-307. doi:10.1016/s0022-460x(70)80020-7Sivagnanasundaram, S., Spence, S., & Early, J. (2013). Map Width Enhancement Technique for a Turbocharger Compressor. Journal of Turbomachinery, 136(6). doi:10.1115/1.4007895Aubry, N. (1991). On the hidden beauty of the proper orthogonal decomposition. Theoretical and Computational Fluid Dynamics, 2(5-6), 339-352. doi:10.1007/bf00271473Wold, S., Esbensen, K., & Geladi, P. (1987). Principal component analysis. Chemometrics and Intelligent Laboratory Systems, 2(1-3), 37-52. doi:10.1016/0169-7439(87)80084-9LIANG, Y. C., LEE, H. P., LIM, S. P., LIN, W. Z., LEE, K. H., & WU, C. G. (2002). PROPER ORTHOGONAL DECOMPOSITION AND ITS APPLICATIONS—PART I: THEORY. Journal of Sound and Vibration, 252(3), 527-544. doi:10.1006/jsvi.2001.4041Abdi, H., & Williams, L. J. (2010). Principal component analysis. Wiley Interdisciplinary Reviews: Computational Statistics, 2(4), 433-459. doi:10.1002/wics.101Nikiforov, V. (2007). The energy of graphs and matrices. Journal of Mathematical Analysis and Applications, 326(2), 1472-1475. doi:10.1016/j.jmaa.2006.03.07
Recommended from our members
Atmospheric electrical field measurements near a fresh water reservoir and the formation of the lake breeze
In order to access the effect of the lakes in the atmospheric electrical field, measurements have been carried out near a large man-made lake in southern Portugal, the Alqueva reservoir, during the ALqueva hydro-meteorological EXperiment 2014. The purpose of these conjoint experiments was to study the impact of the Alqueva reservoir on the atmosphere, in particular on the local atmospheric electric environment by comparing measurements taken in the proximity of the lake. Two stations 10 km apart were used, as they were located up- and down-wind of the lake (Amieira and Parque Solar, respectively), in reference to the dominant northwestern wind direction. The up-wind station shows lower atmospheric electric potential gradient (PG) values than the ones observed in the down-wind station between 12 and 20 UTC. The difference in the atmospheric electric PG between the up-wind and the down-wind station is ~30 V/m during the day. This differential occurs mainly during the development of a lake breeze, between 10 and 18 UTC, as a consequence of the surface temperature gradient between the surrounding land and the lake water. In the analysis presented, a correlation is found between the atmospheric electric PG differences and both wind speed and temperature gradients over the lake, thus supporting the influence of the lake breeze over the observed PG variation in the two stations. Two hypotheses are provided to explain this observation: (1) The air that flows from the lake into the land station is likely to increase the local electric conductivity through the removal of ground dust and the transport of cleaner air from higher altitudes with significant light ion concentrations. With such an increase in conductivity, it is expected to see a reduction of the atmospheric electric PG; (2) the resulting air flow over the land station carries negative ions formed by wave splashing in the lake's water surface, as a result of the so-called balloelectric effect. These negative ions will form a space-charge density (SCD) that can reduce the atmospheric electric PG. A formulation is derived here in order to estimate the local SCD
Behavior of QQ-Plots and Genomic Control in Studies of Gene-Environment Interaction
Genome-wide association studies of gene-environment interaction (GxE GWAS) are becoming popular. As with main effects GWAS, quantile-quantile plots (QQ-plots) and Genomic Control are being used to assess and correct for population substructure. However, in GE work these approaches can be seriously misleading, as we illustrate; QQ-plots may give strong indications of substructure when absolutely none is present. Using simulation and theory, we show how and why spurious QQ-plot inflation occurs in GE GWAS, and how this differs from main-effects analyses. We also explain how simple adjustments to standard regression-based methods used in GE GWAS can alleviate this problem
- …