Essential Oil Composition of Pleurothyrium cinereum Leaves

The essential oil of jigua (Pleurothyrium cinereum, Lauraceae) leaves was extracted by steam distillation and analysed by GC (gas chromatography) and GC/MS (gas chromatography-mass spectrometry). Seventeen compounds were identified. The main components detected were β-caryophyllene (21.3%), caryophyllene oxide (18.7%), guaiol (15.5%), α-cadinene (7.3%), and germacrene-D (6.8%). The composition of essential oil from P. cinereum leaves is in agreement with the chemical composition of several neotropical Lauraceae plants

A Facile Approach toward 8-O-4'-Neolignans: Synthesis of Threo-7',8'-Dihydromachilin D through Jacobsen Epoxidation

 Neolignans are natural phenylpropanoid dimers with C-O-C linkages. Currently, neolignans remain as im­portant synthetic targets due to their reported biological potential against parasites and fungal infections. Thereof, a new approach for the synthesis of the 8-O-4'-neolignan 7',8'-dihydromachilin D based on Jacobsen epoxidation as key step is described here. This stereoselective synthesis proceeded in only 4 steps in 3.9% overall yield. Jacobsen epoxidation was firstly optimized regarding to yield and enantioselectivity employing trans-stilbene as model substrate

Nueva benzoil lactona y otros costituyentes de pilocarpus alvaradoii (rutaceae)

Del extracto etanólico de hojas de Pilocarpus alvaradoii fue aislada e identificada la nueva lactona α-Benzoil-γ-valerolactona (1), junto con los triterpenos pentacíclicos conocidos lupeol (2), epibetulina (3); y las furanocumarinas bergapteno (4), psoraleno (5), y xantotoxina (6).  El aislamiento y la purificación fueron realizados por técnicas cromatográficas convencionales.   La elucidación estructural de estos compuestos se determinó mediante técnicas espectroscópicas (IR, RMN 1H, 13C, EM)

Clasificación de extractos etanólicos de especies de la familia Lauraceae por cromatografía en capa fina bidimensional y análisis estadísticos multivariado CCD-2D/ PCA-cluster

Se caracterizaron los extractos etanólicos de hojas y cortezas de 13 especies de la familia Lauraceae mediante cromatografía en capa fina de dos dimensiones (2D-CCD).  Los datos posteriores se analizaron mediante técnicas de análisis estadístico multivariado (cluster y análisis de componentes principales (PCA)). Lo anterior permitió hacer una distinción entre los extractos obtenidos de diferentes partes de la planta (hojas y cortezas). Se observó, además, que la metodología usada es capaz de diferenciar entre extractos obtenidos a partir de especies de Lauraceae y los de otras familias de plantas.Leaves and barks ethanolic extracts from 13 Lauraceae species were characterized through twohdimensional thin layer chromatography (2D-TLC). The subsequent data was analized through multivariate statistical analysis Techniques (cluster analysis and principal components analysis (PCA)). This allowed to do a distinction between extracts obtained from different parts of the plant (leaves and bark). In addition, it was observed that the implemented methodology is able to differentiate between extracts obtained from Lauraceae species and some obtained from other plant families

Metabolitos aislados de raputia heptaphylla y esenbeckia alata (rutaceae) y síntesis de precursores de análogos de alcaloides quinolínicos

Abstract. Previous studies on the Esenbeckia alata and Raputia heptaphylla,both species belonging to the Rutaceae family, have shownimportant results with respect to their chemistry. These species havesecondary metabolites (coumarins and alkaloids mainly), which act aschemotaxonomic markers. This paper presents, for the first time, the phytochemicalwork and isolated metabolites in these species: four coumarins:bergapten, xanthyletin, xanthotoxin, 3-isoprenyl-4-methoxy-coumarin;four alkaloids: skinmianine, kokusaginine, dictamnine, and 1-methyl-2-methoxy-4-quinolone; two lignans: sesamin and mesodihydroguaiareticacid; two sterols: -sitosterol, stigmasterol; and a pentacyclic triterpene:lupeol that have been isolated from leaves of E. alata. Five alkaloids7-methoxy-2,2-dimethyl-2,6-dihidro-piran[3,2,c] quinolin-5-one, flindersiamine,skinmianine, kokusaginine and dictamnine that have been isolatedfrom leaves of R. heptaphylla. Moreover, it presents a new method byobtaining quinolone alkaloid analogue precursors trough the condensationsof Mannich adduct vinylogous and aldehydes followed by radicalcyclization to obtain products with high regio- and stereoselectivity.

Chemical composition and antimicrobial activity of the essential oil of the leaves of Ocotea caudata (Nees) Mez (Lauraceae) from Colombia

Ocotea is a genus that belong to Lauraceae family, which has about 56 species, distributed in Asia, Africa and mainly in America. The aim of this work was to identify the chemical composition of the essential oil from leaves of Ocotea caudata collected from Colombia. The chemical composition of the oil was determined by gas chromatography-mass spectrometry (GC-MS), being described for the first time. Thirty nine compounds (corresponding to 92.7% of the oil) were identified. The major constituents were germacrene D (55.8%), bicyclogermacrene (8.0%), β-caryophyllene (4.6%) and β-bourbonene (2.3%). Also the antibacterial activity of the oil was evaluated against two Gram (+) and two Gram (-) bacteria showing that the oil exhibited moderated activity against Gram (+) bacteria

Aporfinoides en hojas de oxandra longipetala r. e. fr. (annonaceae)

El estudio químico del extracto de alcaloides totales, realizado por el método clásico, de las hojas de Oxandra longipetala R. E. Fr., colectada en el departamento de Córdoba, Colombia, permitió el aislamiento e identificación de los alcaloides oxoaporfínicos lysicamina, O-metilmoschatolina, atherospermidina y liriodenina, junto con las aporfinas nornuciferina y anonaina. Las estructuras fueron elucidadas por métodos espectroscópicos (IR, RMN-1H, RMN-13C, experimentos 2D, espectrometría de masas) y por comparación con datos de la literatura

5-h¡droxi-2-metil-1,4-naftoquinona obtenida de pera nítida (benth.) jablonski(euforbiaceae)

Del extracto clorofórmico de la corteza del tronco de Pera nítida (Benth.) Jablonski se aisló una sustancia amarilla que fue identificada como 5—hidro.x¡-2— metil —1,4—naftoquinona. Esta sustancia es conocida como plumbagina y ha mostrado una destacada acción biológica. La estructura fue deducida con base en los datos espectroscópicos y su presencia en esta especie tiene importancia quimiotaxonómica