Concentrated suspensions of Brownian beads in water: dynamic heterogeneities trough a simple experimental technique

Concentrated suspensions of Brownian hard-spheres in water are an epitome for understanding the glassy dynamics of both soft materials and supercooled molecular liquids. From an experimental point of view, such systems are especially suited to perform particle tracking easily, and, therefore, are a benchmark for novel optical techniques, applicable when primary particles cannot be resolved. Differential Variance Analysis (DVA) is one such novel technique that simplifies significantly the characterization of structural relaxation processes of soft glassy materials, since it is directly applicable to digital image sequences of the sample. DVA succeeds in monitoring not only the average dynamics, but also its spatio-temporal fluctuations, known as dynamic heterogeneities. In this work, we study the dynamics of dense suspensions of Brownian beads in water, imaged through digital video-microscopy, by using both DVA and single-particle tracking. We focus on two commonly used signatures of dynamic heterogeneities: the dynamic susceptibility, $\chi_4$, and the non-Gaussian parameter, $\alpha_2$. By direct comparison of these two quantities, we are able to highlight similarities and differences. We do confirm that $\chi_4$ and $\alpha_2$ provide qualitatively similar information, but we find quantitative discrepancies in the scalings of characteristic time and length scale on approaching the glass transition.Comment: The original publication is available at http://www.scichina.com and http://www.springerlink.com http://engine.scichina.com/publisher/scp/journal/SCPMA/doi/10.1007/s11433-019-9401-x?slug=abstrac

An Obstacle Problem for Noncoercive Operators

We study the obstacle problem for second order nonlinear equations whose model appears in the stationary diffusion-convection problem. We assume that the growth coefficient of the convection term lies in the Marcinkiewicz spaceweak-LN

Detecting and repairing anomalous evolutions in noisy environments: logic programming formalization and complexity results

In systems where agents are required to interact with a partially known and dynamic world, sensors can be used to obtain further knowledge about the environment. However, sensors may be unreliable, that is, they may deliver wrong information (due, e.g., to hardware or software malfunctioning) and, consequently, they may cause agents to take wrong decisions, which is a scenario that should be avoided. The paper considers the problem of reasoning in noisy environments in a setting where no (either certain or probabilistic) data is available in advance about the reliability of sensors. Therefore, assuming that each agent is equipped with a background theory (in our setting, an extended logic program) encoding its general knowledge about the world, we define a concept of detecting an anomaly perceived in sensor data and the related concept of agent recovering to a coherent status of information. In this context, the complexities of various anomaly detection and anomaly recovery problems are studied.IFIP International Conference on Artificial Intelligence in Theory and Practice - Agents 1Red de Universidades con Carreras en Informática (RedUNCI

Tadalafil improves lean mass and endothelial function in nonobese men with mild ED/LUTS: in vivo and in vitro characterization

PURPOSE: Phosphodiesterase type-5 inhibitor administration in diabetic men with erectile dysfunction (ED) is associated with reduced waist circumference. We evaluated potential effects of daily tadalafil administration on body composition and investigated its possible mechanism(s) of action in C2C12 skeletal muscle cells in vitro. METHODS: Forty-three men on stable caloric intake (mean age 48.5 ± 7; BMI 25.5 ± 0.9 kg/m2) complaining mild ED and/or low urinary tract symptoms (LUTS) were randomly assigned to receive tadalafil (TAD) 5 mg/daily (once-a-day=OAD-TAD; n = 23) or 20 mg on-demand (on-demand=OD-TAD; n = 20) for 2 months. Primary outcomes were variations of body composition measured by Dual-energy X-ray absorptiometry; secondary outcomes were ED/LUTS questionnaire scores along with hormone (testosterone, estradiol, insulin) and endothelial function (Endopat2000) variations. RESULTS: OAD-TAD increased abdominal lean mass (p < 0.01) that returned to baseline after 2 months withdrawal. LUTS scores improved (p<0.01) in OD-TAD while ED scores improved (p < 0.01) in both groups. We found significant improvements in endothelial function (p < 0.05) that directly correlated with serum insulin (p < 0.01; r = 0.3641) and inversely correlated with estradiol levels (p < 0.01; r = 0.3655) even when corrected for potential confounders. Exposure of C2C12 cells upon increasing tadalafil concentrations (10-7 to 10-6 M) increased total androgen receptor mRNA and protein expression as well as myogenin protein expression after 24 and 72 h (2.8 ± 0.4-fold and 1.4 ± 0.02-fold vs. control, respectively, p < 0.05). CONCLUSIONS: Daily tadalafil improved lean mass content in non-obese men probably via enhanced insulin secretion, estradiol reduction, and improvement of endothelial function in vivo. The in vitro increased myogenin and androgen receptor protein expression in skeletal muscle cells suggests a translational action of phosphodiesterase type-5 on this receptor

Resistance traits and AFLP characterization of diploid primitive tuber-bearing potatoes.

ISSN: 0925-986

Diffeomorphic approximation of Planar Sobolev Homeomorphisms in rearrangement invariant spaces

Let $\Omega\subseteq\mathcal{R}^2$ be a domain, let $X$ be a rearrangement invariant space and let $f\in W^{1}X(\Omega,\mathcal{R}^2)$ be a homeomorphism between $\Omega$ and $f(\Omega)$. Then there exists a sequence of diffeomorphisms $f_k$ converging to $f$ in the space $W^{1}X(\Omega,\mathcal{R}^2)$

Noncoercive quasilinear elliptic operators with singular lower order terms

We consider a family of quasilinear second order elliptic differential operators which are not coercive and are defined by functions in Marcinkiewicz spaces. We prove the existence of a solution to the corresponding Dirichlet problem. The associated obstacle problem is also solved. Finally, we show higher integrability of a solution to the Dirichlet problem when the datum is more regular