3,225 research outputs found
[3-Methoxy-1-(phenylsulfanyl)propyl]triphenyltin(IV) benzene 0.17-solvate
In the title compound, [Sn(C6H5)3(C10H13OS)]·0.17C6H6, the SnIV atom exhibits a slightly distorted tetrahedral coordination geometry built up by four C atoms, which are the three ipso-C atoms of the phenyl rings and the α-C atom of the deprotonated γ-O-functionalized propyl phenyl sulfide. The benzene molecule lies about a threefold rotoinversion axis
Progress of the Felsenkeller shallow-underground accelerator for nuclear astrophysics
Low-background experiments with stable ion beams are an important tool for
putting the model of stellar hydrogen, helium, and carbon burning on a solid
experimental foundation. The pioneering work in this regard has been done by
the LUNA collaboration at Gran Sasso, using a 0.4 MV accelerator. In the
present contribution, the status of the project for a higher-energy underground
accelerator is reviewed. Two tunnels of the Felsenkeller underground site in
Dresden, Germany, are currently being refurbished for the installation of a 5
MV high-current Pelletron accelerator. Construction work is on schedule and
expected to complete in August 2017. The accelerator will provide intense, 50
uA, beams of 1H+, 4He+, and 12C+ ions, enabling research on astrophysically
relevant nuclear reactions with unprecedented sensitivity.Comment: Submitted to the Proceedings of Nuclei in the Cosmos XIV, 19-24 June
2016, Niigata/Japa
Tuning the Emission Directionality of Stacked Quantum Dots
The emission directionality of stacks of coupled quantum dots (QDs) is investigated within the framework of 8-band k·p-theory including strain and strain-induced piezoelectricity up to second order. Using an artificial cuboidal QD, we show that the degree of radiation anisotropy can be tuned from −33% to nearly +60% via the structure’s vertical aspect ratio. We then demonstrate that these findings can be transferred to stacked InGaAs QDs whose emission directionality is tailored (i) via the interdot coupling strength given by the separating barrier width and (ii) the number of stacked QDs. Our results enable the design and optimization of top and edge emitters based on stacked QDs.DFG, 43659573, SFB 787: Halbleiter - Nanophotonik: Materialien, Modelle, Bauelement
NephroCheck data compared to serum creatinine in various clinical settings
Figure B: TIMP-2 immunofluorescence staining of tubular cells in the urine sediment of patient #2. (TIF 6713 kb
The new Felsenkeller 5 MV underground accelerator
The field of nuclear astrophysics is devoted to the study of the creation of
the chemical elements. By nature, it is deeply intertwined with the physics of
the Sun. The nuclear reactions of the proton-proton cycle of hydrogen burning,
including the 3He({\alpha},{\gamma})7Be reaction, provide the necessary nuclear
energy to prevent the gravitational collapse of the Sun and give rise to the by
now well-studied pp, 7Be, and 8B solar neutrinos. The not yet measured flux of
13N, 15O, and 17F neutrinos from the carbon-nitrogen-oxygen cycle is affected
in rate by the 14N(p,{\gamma})15O reaction and in emission profile by the
12C(p,{\gamma})13N reaction. The nucleosynthetic output of the subsequent phase
in stellar evolution, helium burning, is controlled by the
12C({\alpha},{\gamma})16O reaction.
In order to properly interpret the existing and upcoming solar neutrino data,
precise nuclear physics information is needed. For nuclear reactions between
light, stable nuclei, the best available technique are experiments with small
ion accelerators in underground, low-background settings. The pioneering work
in this regard has been done by the LUNA collaboration at Gran Sasso/Italy,
using a 0.4 MV accelerator.
The present contribution reports on a higher-energy, 5.0 MV, underground
accelerator in the Felsenkeller underground site in Dresden/Germany. Results
from {\gamma}-ray, neutron, and muon background measurements in the
Felsenkeller underground site in Dresden, Germany, show that the background
conditions are satisfactory for nuclear astrophysics purposes. The accelerator
is in the commissioning phase and will provide intense, up to 50{\mu}A, beams
of 1H+, 4He+ , and 12C+ ions, enabling research on astrophysically relevant
nuclear reactions with unprecedented sensitivity.Comment: Submitted to the Proceedings of the 5th International Solar Neutrino
Conference, Dresden/Germany, 11-14 June 2018, to appear on World Scientific
-- updated version (Figure 2 and relevant discussion updated, co-author A.
Domula added
20 Years of Secretagogin: Exocytosis and Beyond
Calcium is one of the most important signaling factors in mammalian cells. Specific temporal and spatial calcium signals underlie fundamental processes such as cell growth, development, circadian rhythms, neurotransmission, hormonal actions and apoptosis. In order to translate calcium signals into cellular processes a vast number of proteins bind this ion with affinities from the nanomolar to millimolar range. Using classical biochemical methods an impressing number of calcium binding proteins (CBPs) have been discovered since the late 1960s, some of which are expressed ubiquitously, others are more restricted to specific cell types. In the nervous system expression patterns of different CBPs have been used to discern different neuronal cell populations, especially before advanced methods like single-cell transcriptomics and activity recording were available to define neuronal identity. However, understanding CBPs and their interacting proteins is still of central interest. The post-genomic era has coined the term “calciomics,” to describe a whole new research field, that engages in the identification and characterization of CBPs and their interactome. Secretagogin is a CBP, that was discovered 20 years ago in the pancreas. Consecutively it was found also in other organs including the nervous system, with characteristic expression patterns mostly forming cell clusters. Its regional expression and subcellular location together with the identification of protein interaction partners implicated, that secretagogin has a central role in hormone secretion. Meanwhile, with the help of modern proteomics a large number of actual and putative interacting proteins has been identified, that allow to anticipate a much more complex role of secretagogin in developing and adult neuronal cells. Here, we review recent findings that appear like puzzle stones of a greater picture
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