The Effect of Optimally Timed Osteopathic Manipulative Treatment on Length of Hospital Stay in Moderate and Late Preterm Infants: Results from a RCT

Introduction. Little research has been conducted looking at the effects of osteopathic manipulative treatment (OMT) on preterm infants. Aim of the Study. This study hypothesized that osteopathic care is effective in reducing length of hospital stay and that early OMT produces the most pronounced benefit, compared to moderately early and late OMT. A secondary outcome was to estimate hospital cost savings by the use of OMT. Methods. 110 newborns ranging from 32- to 37-week gestation were randomized to receive either OMT or usual pediatric care. Early, moderately early, and late OMT were defined as <4, <9, and <14 days from birth, respectively. Result. Hospital stay was shorter in infants receiving late OMT (−2.03; 95% CI −3.15, −0.91; P<0.01) than controls. Subgroup analysis of infants receiving early and moderately early OMT resulted in shorter LOS (early OMT: −4.16; −6.05, −2.27; P<0.001; moderately early OMT: −3.12; −4.36, −1.89; P<0.001). Costs analysis showed that OMT significantly produced a net saving of €740 (−1309.54, −170.33; P=0.01) per newborn per LOS. Conclusions. This study shows evidence that the sooner OMT is provided, the shorter their hospital stay is. There is also a positive association of OMT with overall reduction in cost of care

Impact of a quality improvement intervention on neonatal mortality in a regional hospital in Burkina Faso

The neonatal period is the most vulnerable time in terms of a child's survival, with mortality during this period accounting for approximately half of the deaths before the age of 5 years. The Neonatal Essential Survival Technology (NEST) project is a program aiming to reduce mortality by improving the quality of neonatal care in sub-Saharan Africa. This study presents the evaluation of the first phase of the NEST intervention program at Saint Camille Hospital Ouagadougou (HOSCO), Burkina Faso, in terms of the reduction in neonatal mortality.This is a retrospective analysis, based on "pre-intervention" data collected in 2015, and "post-intervention" data collected in 2018, including all infants admitted to the neonatal unit of HOSCO. The intervention period (2016 and 2017) comprised a structured quality improvement process conducted by a multidisciplinary working group that focused on improving infrastructure, equipment, training and use of clinical protocols, team working within the neonatal unit and with other hospital departments, and communication with referring healthcare facilities. Mortality data were compared pre- vs. post-intervention using a logistic regression model.The analysis included 1427 infants in the pre-intervention period, and 819 post-intervention. In both time periods, more than 75% of admissions were infants with low birth weight, and nearly 50% were very low birth weight. Post-intervention, while there was a decrease in overall admission, the proportion of multiple births increased from 20% to 24% (The first phase of the NEST quality improvement program was associated with a decrease in mortality in outborn infants admitted to the neonatal unit at HOSCO. Long-term assessment is expected to provide a more comprehensive evaluation of the program in a low-income setting

Nati per Leggere. Leggere \ue8 familiare

Il Progetto nazionale "Nati per Leggere" promuove la lettura ad alta voce per i bambini di et\ue0 compresa tra gli 0 e i 6 anni. Il progetto \ue8 inserito tra le azioni di prevenzione primaria della salute del bambino ed \ue8 stato premiato dal Ministero per i Beni e le Attivit\ue0 Culturali come "Migliore manifestazione di promozione del libro e della lettura di rilevanza nazionale\u201

Nati per Leggere nei Servizi territoriali per l'infanzia e per le famiglie

Realizzazione del progetto "Nati per Leggere" nelle Case Famiglia e Centri per la Famiglia della provincia di Macerata. Formazione degli Operatori/Educatori operanti nelle strutture di accoglienza Famiglie e minori

NATI PER LEGGERE: LEGGERE E\u2019 FAMILIARE

Il Progetto nazionale "Nati per Leggere" promuove la lettura ad alta voce per i bambini di et\ue0 compresa tra gli 0 e i 6 anni. Il progetto \ue8 inserito tra le azioni di prevenzione primaria della salute del bambino ed \ue8 stato premiato dal Ministero per i Beni e le Attivit\ue0 Culturali come "Migliore manifestazione di promozione del libro e della lettura di rilevanza nazionale\u201

Nati per Leggere. Leggere \ue8 familiare

Il Progetto nazionale "Nati per Leggere" promuove la lettura ad alta voce per i bambini di et\ue0 compresa tra gli 0 e i 6 anni. Il progetto \ue8 inserito tra le azioni di prevenzione primaria della salute del bambino ed \ue8 stato premiato dal Ministero per i Beni e le Attivit\ue0 Culturali come "Migliore manifestazione di promozione del libro e della lettura di rilevanza nazionale\u201

The Effect of Optimally Timed Osteopathic Manipulative Treatment on Length of Hospital Stay in Moderate and Late Preterm Infants: Results from a RCT

Introduction. Little research has been conducted looking at the effects of osteopathic manipulative treatment (OMT) on preterm infants. Aim of the Study. This study hypothesized that osteopathic care is effective in reducing length of hospital stay and that early OMT produces the most pronounced benefit, compared to moderately early and late OMT. A secondary outcome was to estimate hospital cost savings by the use of OMT. Methods. 110 newborns ranging from 32-to 37-week gestation were randomized to receive either OMT or usual pediatric care. Early, moderately early, and late OMT were defined as &lt;4, &lt;9, and &lt;14 days from birth, respectively. Result. Hospital stay was shorter in infants receiving late OMT (−2.03; 95% CI −3.15, −0.91; &lt; 0.01) than controls. Subgroup analysis of infants receiving early and moderately early OMT resulted in shorter LOS (early OMT: −4.16; −6.05, −2.27; &lt; 0.001; moderately early OMT: −3.12; −4.36, −1.89; &lt; 0.001). Costs analysis showed that OMT significantly produced a net saving of C740 (−1309.54, −170.33; = 0.01) per newborn per LOS. Conclusions. This study shows evidence that the sooner OMT is provided, the shorter their hospital stay is. There is also a positive association of OMT with overall reduction in cost of care

[Prenatal screening and the prevalence of hepatitis B infection in pregnant women in the Marche Region (Central Italy): differences between ethnic groups]

OBJECTIVES: to evaluate the epidemiology of hepatitis B infection in pregnant women living in the Marche Region (Central Italy), according to the Country of origin. DESIGN: cross sectional observational study conducted from May 2011 to April 2012, which involved 13 of the 15 birthing centres in the Marche region. SETTING AND PARTICIPANTS: serological data of hepatitis B infection were obtained during the execution of mandatory prenatal screening. The total number of pregnant women was of 10,232 of which 7,669 were Italian (74.9%) and 2,563 were foreign (25.1%). MAIN OUTCOME MEASURES: rate of adherence to prenatal serologic screening and prevalence of hepatitis B infection in Italian and foreign pregnant women. The 95% confidence intervals were calculated using the exact method for proportions. The test for proportions was applied to make comparisons between groups significance level: 0.05). RESULTS: the rate of adherence to prenatal serologic screening and the overall prevalence of hepatitis B infection in pregnancy ware 98.6% and 0.8%, respectively. In foreign women, compared to native ones, differences of adherence to screening and the prevalence of infection were significant (96.7% vs. 99.3% and 2.7% vs. 0.2%). The highest prevalence was observed in pregnant women who came from the Western Pacific Region, Eastern Europe, and Africa (7.0%, 4.0%, and 3.3%, respectively). More than half of the cases of pregnant women, positive for hepatitis B surface antigen, were originating in Albania and China (60.6%). The prevalence of hepatitis B infection was significantly higher in pregnant women from China (8.1%), Albania (7.7%), Ukraine (7.2%), and Senegal (6.1%). CONCLUSIONS: the study emphasises the need to organise targeted interventions to facilitate access to prenatal screening programmes to foreign women for better control of hepatitis B infection in the Marche Region

A Multicenter, Randomized, Controlled Trial of Osteopathic Manipulative Treatment on Preterms

<div><p>Background</p><p>Despite some preliminary evidence, it is still largely unknown whether osteopathic manipulative treatment improves preterm clinical outcomes.</p><p>Materials and Methods</p><p>The present multi-center randomized single blind parallel group clinical trial enrolled newborns who met the criteria for gestational age between 29 and 37 weeks, without any congenital complication from 3 different public neonatal intensive care units. Preterm infants were randomly assigned to usual prenatal care (control group) or osteopathic manipulative treatment (study group). The primary outcome was the mean difference in length of hospital stay between groups.</p><p>Results</p><p>A total of 695 newborns were randomly assigned to either the study group (n= 352) or the control group (n=343). A statistical significant difference was observed between the two groups for the primary outcome (13.8 and 17.5 days for the study and control group respectively, p<0.001, effect size: 0.31). Multivariate analysis showed a reduction of the length of stay of 3.9 days (95% CI -5.5 to -2.3, p<0.001). Furthermore, there were significant reductions with treatment as compared to usual care in cost (difference between study and control group: 1,586.01€; 95% CI 1,087.18 to 6,277.28; p<0.001) but not in daily weight gain. There were no complications associated to the intervention.</p><p>Conclusions</p><p>Osteopathic treatment reduced significantly the number of days of hospitalization and is cost-effective on a large cohort of preterm infants.</p></div

Description of the study population at the enrollment.

<p>RDS: respiratory distress syndrome. DRG: diagnosis related groups at discharge. PROM: premature rupture of membrane. Numbers are mean(sd). P value from t-test.</p><p>*n(%), p value from chi-square test.</p><p>^§complications were classified according to ICD-9 codes.</p><p>^§§pregnancy data were classified according to ICD-9 diagnosis codes.</p><p>**n(%), p value from Fisher exact test.</p><p>Description of the study population at the enrollment.</p