46 research outputs found
Transforming medical equipment management in digital public health: a decision-making model for medical equipment replacement
IntroductionIn the rapidly evolving field of digital public health, effective management of medical equipment is critical to maintaining high standards of healthcare service levels and operational efficiency. However, current decisions to replace large medical equipment are often based on subjective judgments rather than objective analyses and lack a standardized approach. This study proposes a multi-criteria decision-making model that aims to simplify and enhance the medical equipment replacement process.MethodsThe researchers developed a multi-criteria decision-making model specifically for the replacement of medical equipment. The model establishes a system of indicators for prioritizing and evaluating the replacement of large medical equipment, utilizing game theory to assign appropriate weights, which uniquely combines the weights of the COWA and PCA method. In addition, which uses the GRA method in combination with the TOPSIS method for a more comprehensive decision-making model.ResultsThe study validates the model by using the MRI equipment of a tertiary hospital as an example. The results of the study show that the model is effective in prioritizing the most optimal updates to the equipment. Significantly, the model shown a higher level of differentiation compared to the GRA and TOPSIS methods alone.DiscussionThe present study shows that the multi-criteria decision-making model presented provides a powerful and accurate tool for optimizing decisions related to the replacement of large medical equipment. By solving the key challenges in this area as well as giving a solid basis for decision making, the model makes significant progress toward the field of management of medical equipment
Assessing the influence of humic acids on the weathering of galena and its environmental implications
Galena weathering often occurs in nature and releases metal ions during the process. Humic acid (HA), a critical particle of natural organic matter, binds metal ions, thus affecting metal transfer and transformation. In this work, an electrochemical method combined with spectroscopic techniques was adopted to investigate the interfacial processes involved in galena weathering under acidic and alkaline conditions, as well as in the presence of HA. The results show that the initial step of galena weathering involved the transformation Pb2+ and regardless of whether the solution was acidic or alkaline. Under acidic conditions, S degrees and Pb2+ further transform into anglesite, and HA adsorbs on the galena surface, inhibiting the transformation of sulfur. HA and Pb (II) ions form bridging complexes. Under alkaline conditions without HA, the sulfur produced undergoes no transformation, whereas Pb2+ will transform into PbO. The presence of HA changes the galena weathering mechanism via ionization effect, and Pb2+ is ultimately converted into anglesite. Higher acidity in acidic conditions or higher alkalinity in alkaline conditions causes galena corrosion when the electrolyte does not contain HA. Conversely, higher pH always accelerates galena corrosion when the electrolyte contains HA, whether the electrolyte is acidic or alkaline. At the same acidity/alkalinity, increasing the concentration of HA inhibits galena weathering. Galena will release 134.7 g m(-2).y(-1) Pb2+ to solution at pH 2.5, and the amount decreases to 28.09 g m(-2).y(-1) in the presence of 1000 mg/L HA. This study provides an in situ electrochemical method for the assessment of galena weathering
Overcapacity-driven regional waste incineration facility network planning with residential land value maximization involved: a case study of Shanghai, China
The effective implementation of garbage classification policies in metropolises appears to bring the government into a new quandary about the overcapacity of regional waste incineration facilities (WIFs). This paper proposes a bi-objective robust optimization model to replan the WIFs’ location and their logistics network toward operational cost minimization and regional residential land value maximization. Shanghai is selected as a real-case, and the garbage classification rate and house price fluctuation coefficient are considered as uncertain parameters. All Pareto solutions depict that the regional residential land value released by WIF's closure and subsequent "Not in My Back Yard" effect mitigation is huge, ranging from 74 to 102 billion yuan. Furthermore, the trade-off's robust solutions show that keeping 3 WIFs in the suburbs essentially maximizes the land value, while keeping 6 WIFs evenly distributed throughout the city has the lowest operating cost. Notably, the robust model has good anti-disturbance and the ability to adapt to external changes. As the population migrates to five new cities from the central city and reaches its peak, similar Pareto solutions are observed as those in the baseline scenario without the influence of policies
Red yeast rice preparations for dyslipidemia: An overview of systematic reviews and network meta-analysis
This research was to summarize the comparative efficacy and safety of red yeast rice (RYR) preparations and analyze the treatment ranking of lipid-lowering agents including RYR. Thirty-one systematic reviews (SRs) involving 165 randomized trials with 14,987 dyslipidemia participants were included. All the SRs showed a high overall risk of bias. A Bayesian network meta-analysis was performed. Only five trials reported major adverse cardiovascular events (MACE) and three trials reported lipoprotein(a)[Lp(a)]. Compared to placebo or other lipid-lowering drugs, RYR preparations showed some regulating action on lipids and glucose metabolism, with fewer side effects (P < 0.05). Compared to placebo, RYR showed a tendency to reduce Lp(a) levels. Lipid-lowering agents ranked differently in each outcome. High-quality evidence showed RYR (Zhibituo) lowered total cholesterol and triglyceride levels more than placebo. This study reveals the efficacy and safety ranking of RYR preparations for dyslipidemia, and it’s recommended that future trials should focus on MACE and Lp(a)
Formation of the Chalukou High Fluorine-Type Mo (–Zn–Pb) Deposit, NE China: Constraints from Fluorite and Sphalerite Rare Earth Elements and Sr–Nd Isotope Compositions
Fluorite is a widespread mineral in porphyry and hydrothermal vein Mo-polymetallic deposits. Here, fluorite is utilised as a probe to trace the fluid source and reveal the fluid evolution process in the Chalukou giant Mo (Pb–Zn) deposit, Northeast China, which is characterised as early porphyry Mo and later vein-style Zn–Pb mineralisation. A detailed rare earth element (REE) and Sr–Nd isotope study of fluorite combined with Sr isotopes of sphalerite is conducted for the Chalukou deposit. The chondrite-normalised REE patterns of fluorites from molybdenite veins show light REE (LREE)-enriched patterns, with negative Eu anomalies (δEu = 0.60) and weakly negative Y anomalies (Y/Y* = 0.72). The fluorites associated with sphalerite veins exhibit rare earth element (REE)-flat patterns with negative Eu anomalies (δEu = 0.65 to 0.99) and positive Y anomalies (Y/Y* = 1.37 to 3.08). In addition, during the progression from Mo to Zn–Pb mineralisation, the total concentration of REEs decreases from 839 ppm to 53.7 ppm, and Y/Ho ratios increase from 22.1 to 92.5. These features may be explained by the different mobilities of REE complexes during fluid migration. The Eu anomalies are considered to be inherited from source fluids. All the initial 87Sr/86Sr ratios of fluorite and sphalerite are between those of ore-forming porphyries and wall rocks (rhyolite), with fluorite ratios ranging from 0.706942 to 0.707386 and sphalerite ratios varying from 0.705221 to 0.710417. The majority of εNd(t) values of fluorite varying from −6.4 to −3.6 are also located between the ratios exhibited by ore-forming porphyries and rhyolite, whereas three εNd(t) values of fluorites ranging from −0.26 to 0.36 are close to those of ore-forming porphyries. All the isotopic features indicate that the Sr-Nd isotope ratios of hydrothermal fluid are derived from porphyries and disturbed by fluid–rock reactions. Together with a two-stage Sr–Nd isotope mixing model, we suggest that different sources and fluid–rock interactions (syn-ore intrusions and strata) finally influence the Sr–Nd isotopes of the ore-forming fluids, which are recorded by the majority of fluorite and sphalerite
In situ TEM observation of crystal structure transformation in InAs nanowires on atomic scale
In situ transmission electron microscopy investigation of structural transformation in III-V nanowires is essential for providing direct insight into the structural stability of III-V nanowires under elevated temperature. In this study, through in situ heating investigation in a transmission electron microscope, the detailed structural transformation of InAs nanowires from wurtzite structure to zinc-blende structure at the catalyst/nanowire interface is witnessed on the atomic level. Through detailed structural and dynamic analysis, it was found that the nucleation site of each new layer of InAs and catalyst surface energy play a decisive role in the growth of the zinc-blende structure. This study provides new insights into the growth mechanism of zinc-blende-structured III-V nanowires
Phase boundary and annealing dependent piezoelectricity in lead-free (K,Na)NbO3 nanorod arrays
Orthorhombic (K,Na)NbO3 (KNN) nanorod arrays with the [110]-orientation were grown on SrTiO3 substrates by the hydrothermal method. The nanorods exhibited greatly enhanced piezoelectric performance, with the d33 piezoelectric coefficient increasing from 140 pm/V to 360 pm/V, after annealing in oxygen at temperatures ranging from 500 °C to 800 °C. The high temperature annealing process was accompanied by severe volatilization of K, which modified the K/Na ratio closer to 1:1. Thus, orthorhombic-tetragonal (O-T) phase boundaries appeared, which improved the piezoelectric property. Moreover, surface oxygen vacancies were passivated in the high-temperature oxygen atmosphere, which would reduce the charge density in the nanorods and contribute to the enhanced piezoelectricity. Therefore, excellent piezoelectricity in the KNN nanorod arrays was driven by the combination of the O-T phase boundaries and the oxygen vacancy passivation. This work demonstrates that KNN has great potential in piezoelectric materials area
Long Non-Coding RNA <i>ENST00000508435</i> Promotes Breast Cancer Chemoresistance Through Pyroptosis Inhibition
A microfluidic system simulating physiological fluid environment for studying the degradation behaviors of magnesium-based materials
Magnesium (Mg)-based materials have excellent potential for application in biodegradable vascular stents. Before application, all these materials need to be screened and optimized, especially the screening of corrosion resistance, which is one of the key indicators for stent material screening. Based on the characteristics of the structure of the stent, we focus on the study of the corrosion and degradation behavior of the micron-scale stent struts in the simulated in vivo environment. The struts are simplified into Mg-based wires, and a microfluidic system is established to provide near physiological conditions. A flow-induced shear stress (FISS) of approximately 0.68 Pa close to the wall shear stress of the human coronary artery is applied to the sample surface relying on the microfluidic system. The degradation behaviors of Mg-based wire samples close to the size of struts are studied simultaneously parallel under FISS conditions using this microfluidic system. The immersion test and in vivo experiments demonstrated the feasibility of this microfluidic system for studies of the degradation behavior of Mg-based materials under simulated physiological conditions. In addition, it was also investigated that the effect of degradation products produced under dynamic conditions on vascular cell behavior. The results show that the degradation rate is significantly accelerated under the effect of FISS in the in vitro study, the degradation rate is obviously higher than that in vivo, and AZ31 has the fastest degradation rate compared with pure magnesium and Mg–Zn–Y–Nd alloys. Taken together, this microfluidic system can be used to evaluate and screen the corrosion resistance of Mg-based materials, providing a basis for the design and optimization of Mg-based cardiovascular stent materials
Evolution of the composition, structure, and piezoelectric performance of (K1-xNax)NbO3nanorod arrays with hydrothermal reaction time
Lead-free (K,Na)NbO 3 (KNN) nanorod arrays were synthesized with the assistance of a Nb: SrTiO 3 single-crystal substrate through the hydrothermal process. The evolutions of the morphology, composition, and structure of the as-synthesized KNN nanorods with the increase in reaction time were investigated. The results confirmed that the increase in reaction time up to 3 h led to the increase in the length and aspect ratio of the well-aligned KNN nanorods. All samples have K-rich orthorhombic crystal structures, while the diffraction peaks shifted towards a higher degree. The peak shifts should be attributed to the increase in the Na content in the KNN lattice, which could decrease the lattice parameters owing to the small ionic radius of Na + than that of K + . Moreover, the increase in reaction time also resulted in the suppression of oxygen vacancies on the surface of the KNN nanorods. These evolutions of the composition and crystal structure, as well as the decrease in the defect content, lead to great enhancement of the nanorod\u27s piezoelectric response, as their d 33 value was increased from 19 to 64 pm/V. These results demonstrated the significant impact of reaction time on the hydrothermal growth of high-performance lead-free KNN one-dimensional nanomaterials