Mesoscopic numerical simulation of the mechanical properties of concrete creep

In order to carry out creep mechanism research on concrete under mesoscopic scales, Monte Carlo method has been used to put forward the meshing method of aggregate and mortar under mesoscopic scales, while combining the theory of mixture and the porous medium theory to establish the composite material model of aggregate, cement mortar and the moisture content under mesoscopic scales. Concrete aggregate random distribution and meshing program and concrete creep simulation analysis program under meso-scale have been prepared. The simulation analysis shows that the program can effectively simulate law of creep motion inside the concrete

An Extended Virtual Aperture Imaging Model for Through-the-wall Sensing and Its Environmental Parameters Estimation

Through-the-wall imaging (TWI) radar has been given increasing attention in recent years. However, prior knowledge about environmental parameters, such as wall thickness and dielectric constant, and the standoff distance between an array and a wall, is generally unavailable in real applications. Thus, targets behind the wall suffer from defocusing and displacement under the conventional imag¬ing operations. To solve this problem, in this paper, we first set up an extended imaging model of a virtual aperture obtained by a multiple-input-multiple-output array, which considers the array position to the wall and thus is more applicable for real situations. Then, we present a method to estimate the environmental parameters to calibrate the TWI, without multiple measurements or dominant scatter¬ers behind-the-wall to assist. Simulation and field experi¬ments were performed to illustrate the validity of the pro¬posed imaging model and the environmental parameters estimation method

Protein-Protein Affinity Determination by Quantitative FRET Quenching.

The molecular dissociation constant, Kd, is a well-established parameter to quantitate the affinity of protein-protein or other molecular interactions. Recently, we reported the theoretical basis and experimental procedure for Kd determination using a quantitative FRET method. Here we report a new development of Kd determination by measuring the reduction in donor fluorescence due to acceptor quenching in FRET. A new method of Kd determination was developed from the quantitative measurement of donor fluorescence quenching. The estimated Kd values of SUMO1-Ubc9 interaction based on this method are in good agreement with those determined by other technologies, including FRET acceptor emission. Thus, the acceptor-quenched approach can be used as a complement to the previously developed acceptor excitation method. The new methodology has more general applications regardless whether the acceptor is an excitable fluorophore or a quencher. Thus, these developments provide a complete methodology for protein or other molecule interaction affinity determinations in solution

The Effects of the Tractor and Semitrailer Routing Problem on Mitigation of Carbon Dioxide Emissions

The incorporation of CO2 emissions minimization in the vehicle routing problem (VRP) is of critical importance to enterprise practice. Focusing on the tractor and semitrailer routing problem with full truckloads between any two terminals of the network, this paper proposes a mathematical programming model with the objective of minimizing CO2 emissions per ton-kilometer. A simulated annealing (SA) algorithm is given to solve practical-scale problems. To evaluate the performance of the proposed algorithm, a lower bound is developed. Computational experiments on various problems generated randomly and a realistic instance are conducted. The results show that the proposed methods are effective and the algorithm can provide reasonable solutions within an acceptable computational time

The spin measurement of MAXI J1348-630 using the Insight-HXMT data

We report the results of fitting Insight-HXMT data to the black hole X-ray binary MAXI J1348-430, which was discovered on January 26th, 2019, with the Gas Slit Camera (GSC) on-board MAXI. Several observations at the beginning of the first burst were selected, with a total of 10 spectra. From the residuals of fits using disk plus power law models, X-ray reflection signatures were clearly visible in some of these observations. We use the state-of the-art relxill series reflection model to fit six spectra with distinct reflection signatures and a joint fit to these spectra. In particular, we focus on the results for the black hole spin values. Assuming Rin = RISCO, the spin parameter is constrained to be 0.82+0.04-0.03 with 90% confidence level (statistical only).Comment: Revisions to MNRAS are submitted, and comments are welcome