2,098 research outputs found
Tabulator Redux: writing Into the Semantic Web
A first category of Semantic Web browsers were designed to present a given dataset (an RDF graph) for perusal, in various forms. These include mSpace, Exhibit, and to a certain extent Haystack. A second category tackled mechanisms and display issues around linked data gathered on the fly. These include Tabulator, Oink, Disco, Open Link Software's Data Browser, and Object Browser. The challenge of once that data is gathered, how might it be edited, extended and annotated has so far been left largely unaddressed. This is not surprising: there are a number of steep challenges for determining how to support editing information in the open web of linked data. These include the representation of both the web of documents and the web of things, and the relationships between them; ensuring the user is aware of and has control over the social context such as licensing and privacy of data being entered, and, on a web in which anyone can say anything about anything, helping the user intuitively select the things which they actually wish to see in a given situation. There is also the view update problem: the difficulty of reflecting user edits back through functions used to map web data to a screen presentation. In the latest version of the Tabulator project, described in this paper we have focused on providing the write side of the readable/writable web. Our approach has been to allow modification and addition of information naturally within the browsing interface, and to relay changes to the server triple by triple for least possible brittleness (there is no explicit 'save' operation). Challenges which remain include the propagation of changes by collaborators back to the interface to create a shared editing system. To support writing across (semantic) Web resources, our work has contributed several technologies, including a HTTP/SPARQL/Update-based protocol between an editor (or other system) and incrementally editable resources stored in an open source, world-writable 'data wiki'. This begins enabling the writable Semantic Web
Together we do not forget: co-designing with people living with dementia towards a design for social inclusion
Dislocation constriction and cross-slip in Al and Ag: an ab initio study
A novel model based on the Peierls framework of dislocations is developed.
The new theory can deal with a dislocation spreading at more than one slip
planes. As an example, we study dislocation cross-slip and constriction process
of two fcc metals, Al and Ag. The energetic parameters entering the model are
determined from ab initio calculations. We find that the screw dislocation in
Al can cross-slip spontaneously in contrast with that in Ag, which splits into
partials and cannot cross-slip without first being constricted. The dislocation
response to an external stress is examined in detail. We determine dislocation
constriction energy and critical stress for cross-slip, and from the latter, we
estimate the cross-slip energy barrier for the straight screw dislocations
Differentiation of Murine Embryonic Stem Cells to Thyrocytes Requires Insulin and Insulin-like Growth Factor-1
[Abstract] The mechanisms controlling thyrocyte development during embryonic stem (ES) cell differentiation have only been partially elucidated, although previous studies have suggested the participation of thyroid stimulating hormone (TSH) in these processes. To further define the role of TSH in this context, we have studied a murine ES cell line in which green fluorescent protein (GFP) cDNA is targeted to the TSH receptor (TSHR) gene, linking the expression of GFP to the transcription of the endogenous TSHR gene. We demonstrate that, in the initial stages of embryoid body formation, activin A and TSH induce the differentiation of definitive endoderm and thyrocyte progenitors expressing Sox17, Foxa2, and TSHR. These thyrocyte progenitors are then converted into cellular aggregates that, in the presence of insulin and IGF-1, further differentiate into mature thyroglobulin-expressing thyrocytes. Our data suggest that, despite the fact that TSH is important for the induction and specification of thyrocytes from ES cells, insulin and IGF-1 are crucial for thyrocyte maturation. Our method provides a powerful in vitro differentiation model for studying the mechanisms of early thyrocyte lineage development.United States. National Institutes of Health; DK06805
A Human Situation Awareness Support System to Avoid Technological Disasters
In many complex technological systems, accidents have primarily been attributed to human error. In the majority of these accidents the human operators were striving against significant challenges. They have to face data overload, the challenge of working with a complex system and the stressful task of understanding what is going on in the situation. Therefore, to design and implement complex technological systems where the information flow is quite high, and poor decisions may lead to serious consequences, Situation Awareness (SA) should be appropriately considered. A level 1 SA is highly supported in these systems through the various heterogeneous sensors and signal-processing methods but, for levels 2 and 3 there is still a need for concepts and methods. This work develops a system called the Human Situation Awareness Support System (HSASS) that supports the safety operators in an ever increasing amount of available risky status and alert information. The proposed system includes a new dynamic situation assessment method based on risk, which has the ability to support the operators understanding of the current state of the system, predict the near future, and suggest appropriate actions. The proposed system does not control the course of action and allows the human to act at his/her discretion in specific contexts
Identifying factors for personalized strategies to motivate seniors to adopt a more active lifestyle
Purpose Sedentary lifestyles threaten the independence and wellbeing of the rapidly growing senior population1. This lack of physical activity contributes to symptoms of frailty2. Maintaining or increasing physical activity has many benefits3 and can increase senior independence3. The value of personal profiling (context of work, personal traits ...e tc.) according to personal drivers toward behavioral intention i s accepted. User profiling relates to the goal that the user aims to reach, while psychological factors relate to motivation towards behavior changes6. It is therefore necessary to investigate which profiling factors are important to create personalized motivational strategies for promotion of physical activities. Method In this observational study, community dwelling senior members of a local Dutch senior community center were asked to wear the Xiaomi Band step counters and record their daily activities in diary-like cultural probe with both open and closed questions. Personal trait information, including age, gender, their perceived age, perceived health, participant stage of change7 and their Regulatory Focus8, was collected at the beginning and end of the 3-month test period. Results & Discussion Of the 52 seniors initially recruited, 44 submitted diaries and 15 yielded complete step data. To explore the relationship between participant's personal traits and activities, a word search on the qualitative data from the diaries was done to find how often participants mentioned high, moderate and low intensity physical activity. The number of references which male and female participants made about these levels of physical activity was compared using a non-parametric test correlation analysis using Spearman's rho correlation efficient. With 95% confidence, this analysis implied that female participants undertook a higher diversity of physical activity in terms of intensity compared to male participants (Spearman's rho=0.878). This result suggests that gender is one important profiling factor concerning the promotion of physical activity. A similar analysis was conducted to examine the level of physical activity reported compared to participant's level of perceived health. This analysis indicated, with 99% confidence (Spearman's rho=0.698), that participants with higher perceived health undertook activities with more diverse levels of physical intensity. Further research is needed to see if health or self-efficacy could cause this correlation. In a linear regression analysis, no significant difference was found between the number of steps participants with a different regulatory focus8 (promotion or prevention) made. The number of steps participants completed was correlated with the months that the steps were taken in (February, March, or April). This could be possibly due to the improved weather and could suggest that personalized strategies addressing participant's environment or context can also increase motivation to physical activity
The generalized second law for the interacting generalized Chaplygin gas model
We investigate the validity of the generalized second law (GSL) of
gravitational thermodynamics in a non-flat FRW universe containing the
interacting generalized Chaplygin gas with the baryonic matter. The dynamical
apparent horizon is assumed to be the boundary of the universe. We show that
for the interacting generalized Chaplygin gas as a unified candidate for dark
matter (DM) and dark energy (DE), the equation of state parameter can cross the
phantom divide. We also present that for the selected model under thermal
equilibrium with the Hawking radiation, the GSL is always satisfied throughout
the history of the universe for any spatial curvature, independently of the
equation of state of the interacting generalized Chaplygin gas model.Comment: 8 page
Revisiting Generalized Chaplygin Gas as a Unified Dark Matter and Dark Energy Model
In this paper, we revisit generalized Chaplygin gas (GCG) model as a unified
dark matter and dark energy model. The energy density of GCG model is given as
,
where and are two model parameters which will be constrained by
type Ia supernova as standard candles, baryon acoustic oscillation as standard
rulers and the seventh year full WMAP data points. In this paper, we will not
separate GCG into dark matter and dark energy parts any more as adopted in the
literatures. By using Markov Chain Monte Carlo method, we find the result:
and .Comment: 6 pages, 4 figure
Combined constraints on modified Chaplygin gas model from cosmological observed data: Markov Chain Monte Carlo approach
We use the Markov Chain Monte Carlo method to investigate a global
constraints on the modified Chaplygin gas (MCG) model as the unification of
dark matter and dark energy from the latest observational data: the Union2
dataset of type supernovae Ia (SNIa), the observational Hubble data (OHD), the
cluster X-ray gas mass fraction, the baryon acoustic oscillation (BAO), and the
cosmic microwave background (CMB) data. In a flat universe, the constraint
results for MCG model are,
()
,
()
,
()
,
()
, and ()
.Comment: 12 pages, 1figur
Distribution and density of the partition function zeros for the diamond-decorated Ising model
Exact renormalization map of temperature between two successive decorated
lattices is given, and the distribution of the partition function zeros in the
complex temperature plane is obtained for any decoration-level. The rule
governing the variation of the distribution pattern as the decoration-level
changes is given. The densities of the zeros for the first two
decoration-levels are calculated explicitly, and the qualitative features about
the densities of higher decoration-levels are given by conjecture. The Julia
set associated with the renormalization map is contained in the distribution of
the zeros in the limit of infinite decoration level, and the formation of the
Julia set in the course of increasing the decoration-level is given in terms of
the variations of the zero density.Comment: 8 pages,8figure
- …