56 research outputs found

    Synthesis of ultra-narrow PbTe nanorods with extremely strong quantum confinement

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    Monodisperse, high-quality, ultra-narrow PbTe nanorods were synthesized for the first time in a one-pot, hot-injection reaction using trans-2-decenoic acid as the agents for lead precursors and tris(diethylamino)phosphine telluride together with free tris(diethylamino)phosphine as the telluride precursors. High monomer reactivity, rapid nucleation and fast growth rate derived from the new precursors led to the anisotropic growth of PbTe nanocrystals at low reaction temperatures

    High expression of nucleophosmin is closely related to the grade and invasion of colorectal cancer

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    420-426This study explores the differential protein expression in the colorectal cancer (CRC) patients to validate a new biomarker for tumor progression. CRC tissues and their adjacent non-cancerous tissues were analyzed by two-dimensional LC/MS/MS. Nucleophosmin 1 (NPM1) was selected and confirmed its differential expression by Western blot. Immunohistological staining of NPM1 in tissues was performed to validate its correlation with clinicopathologic parameters of CRC patients. There were 39 candidates with significant difference between cancerous tissues and their adjacent non-cancerous tissues, which included 19 increased proteins and 20 decreased proteins in CRC samples. Especially, NPM1 was correlated with poor differentiation, and lymph node metastasis according to the analysis of patients’ clinicopathologic parameters. Increased expression of NPM1 can be as a critical biomarker for clinical diagnosis of tumor progression of CRC patients

    High expression of nucleophosmin is closely related to the grade and invasion of colorectal cancer

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    To explore the differential protein expression in the colorectal cancer (CRC) patients to validate a new biomarker for tumor progression. CRC tissues and their adjacent non-cancerous tissues were analyzed by two-dimensional LC/MS/MS. Nucleophosmin 1 (NPM1) was selected and confirmed its differential expression by Western blot. Immunohistological staining of NPM1 in tissues was performed to validate its correlation with clinicopathologic parameters of CRC patients. There were 39 candidates with significant difference between cancerous tissues and their adjacent non-cancerous tissues, which included 19 increased proteins and 20 decreased proteins in CRC samples. Especially, NPM1 was correlated with poor differentiation, and lymph node metastasis according to the analysis of patients’ clinicopathologic parameters. Increased expression of NPM1 can be as a critical biomarker for clinical diagnosis of tumor progression of CRC patients

    The Temporal Evolution of Coastlines in the Bohai Sea and Its Impact on Hydrodynamics

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    Over the past 40 years, increasing coastal reclamation and natural sedimentation has changed coastline positions and resulted in variation in the hydrodynamic environment in the Bohai Sea (BHS), China. Based on the Landsat series images, an interpretative identifier for identifying the coastline was proposed to assess the hydrodynamic changes caused by the coastline change and was applied to a typical case of the Bohai Sea (BHS), China. We combined a grid-based coastline position with an adjoint data assimilation method to seamlessly map the distribution of the amplitude, phase lag, and tidal current of the M2 tidal constituent along the BHS’s coast from 1985 to 2018. Our findings reveal that the coastline change at long time scales dominated reclamation, and around 72.9% of the coastline of the BHS mapped in 2018 had seaward movement compared with its position in 1985. From 1985 to 2018, the BHS volume decreased by 0.17%, the sea surface area decreased by 4.54%, and the kinetic energy increased by 2.53%. The change in the coastline increased the amplitude of the M2 tidal constituent in the Bohai Bay by 6–14 cm and increased the residual current in the eastern coast of the Liaodong Bay by up to 0.07 (0.01) m/s

    Multi-Physics Multi-Objective Optimal Design of Bearingless Switched Reluctance Motor Based on Finite-Element Method

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    The bearingless switched reluctance motor (BSRM) integrates the switched reluctance motor (SRM) with the magnetic bearings, which avoids mechanical bearings-loss and makes it promising in high-speed applications. In this paper, a comprehensive framework for the multi-physics multi-objective optimal design of BSRMs based on finite-element method (FEM) is proposed. At first, the 2-D electromagnetic model of a fabricated initial design prototype is built and solved by the open-source FEM software, Elmer. The iron loss model in Elmer based on the Fourier series is modified by a transient iron loss model with less computation time. Besides, a simplified lumped-parameter (LP) thermal model of the BSRM is applied to estimate the temperature rise of BSRM in the steady state. Then, the comprehensive framework for the multi-physics multi-objective optimal design of BSRMs based on FEM is proposed. The objectives, constraints, and decision variables for optimization are determined. The multi-objective genetic particle swarm optimizer is utilized to obtain the Pareto front of optimization. The electromagnetic performance of the final optimal design is compared with the initial design. Comparison results show that the average electromagnetic torque and the efficiency are significantly enhanced

    The Temporal Evolution of Coastlines in the Bohai Sea and Its Impact on Hydrodynamics

    No full text
    Over the past 40 years, increasing coastal reclamation and natural sedimentation has changed coastline positions and resulted in variation in the hydrodynamic environment in the Bohai Sea (BHS), China. Based on the Landsat series images, an interpretative identifier for identifying the coastline was proposed to assess the hydrodynamic changes caused by the coastline change and was applied to a typical case of the Bohai Sea (BHS), China. We combined a grid-based coastline position with an adjoint data assimilation method to seamlessly map the distribution of the amplitude, phase lag, and tidal current of the M2 tidal constituent along the BHS’s coast from 1985 to 2018. Our findings reveal that the coastline change at long time scales dominated reclamation, and around 72.9% of the coastline of the BHS mapped in 2018 had seaward movement compared with its position in 1985. From 1985 to 2018, the BHS volume decreased by 0.17%, the sea surface area decreased by 4.54%, and the kinetic energy increased by 2.53%. The change in the coastline increased the amplitude of the M2 tidal constituent in the Bohai Bay by 6–14 cm and increased the residual current in the eastern coast of the Liaodong Bay by up to 0.07 (0.01) m/s

    Effects of ocean eddies on the tropical storm Roanu intensity in the Bay of Bengal.

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    A tropical storm (TS) Roanu occurred in northern Sri Lanka in 2016, which transported northwards along the west coast of the Bay of Bengal (BoB). During the development of the TS, ocean eddies on its track had an important effect on the intensity of Roanu. The dynamic mechanism was investigated with multisource reanalysis and Argo float data in this study. The results show that ocean eddies were the main reason why Roanu first enhanced, weakened, and then enhanced again. Warm eddy W1 supports the initial development of the TS, cold eddy C1 weakens Roanu, and warm eddy W2 continues to support Roanu. On May 19, 2016, the maximum average latent heat flux over W1 was 260.85 w/m2, while that of C1 was only 200.71 w/m2. After the passage of Roanu, the tropical cyclone heat potential (TCHP) of eddies significantly decreased. The TCHP of W1, W2, C1 and C2 decreased by 20.95 kJ/cm2, 11.07 kJ/cm2, 29.82 kJ/cm2, 9.31 kJ/cm2, respectively. The mixed layer of warm eddies deepened much more than that of cold eddies, supporting Roanu development. In addition, changes in potential vorticity (PV) values caused by the disturbance of eddies may also reflect changes in the TS intensity. This study offers new insights on the influence of ocean eddies in regulating the development of tropical cyclone (TC) in the BoB

    A Magnetic Record of Heavy Metal Pollution in the Yangtze River Subaqueous Delta

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    The rapid industrial development in the Yangtze River watershed over the last several decades has drawn great attention with respect to heavy metal pollution to the Yangtze River estuary and nearby coastal areas. In this study, a 236cm long sediment core was retrieved from the Yangtze River subaqueous delta (122°36\u27 E, 31°00\u27 N) in 2008 and analyzed for magnetic properties and geochemical compositions to investigate heavy metal pollution history. The activity of 137Cs peaked at depth 140cm, with a broad plateau between 120cm and 140cm, suggesting an average sedimentation rate of 3.11cmyr-1 for the upper 140cm layer. Magnetic susceptibility (χ), saturation isothermal remanent magnetization (SIRM), anhysteretic remanent magnetization (χARM) and heavy metal enrichment factors (EF) all showed an upward increase trend above depth 140cm, suggesting that increased ferrimagnetic mineral concentration was accompanied by heavy metal enrichment in the sediment. Geochemical and granolumetric analyses showed that sediment sources and particle sizes played minor roles in the variations of magnetic properties. The effect of diagenesis, which can lead to the selective removal of magnetic minerals, was noticeable in the lower part of the core (140-236cm). Co-variation between magnetic properties (χ, SIRM and χARM) and EF of Cu and Pb suggests that the elevated ferrimagnetic mineral concentration can be used as an indicator of heavy metal pollution in the reconstruction of environmental changes in estuarine and coastal settings
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