Human activities accelerated the degradation of saline seepweed red beaches by amplifying top‐down and bottom‐up forces

Salt marshes dominated by saline seepweed (Suaeda heteroptera) provide important ecosystem services such as sequestering carbon (blue carbon), maintaining healthy fisheries, and protecting shorelines. These salt marshes also constitute stunning red beach landscapes, and the resulting tourism significantly contributes to the local economy. However, land use change and degradation have led to a substantial loss of the red beach area. It remains unclear how human activities influence the top‐down and bottom‐up forces that regulate the distribution and succession of these salt marshes and lead to the degradation of the red beaches. We examined how bottom‐up forces influenced the germination, emergence, and colonization of saline seepweed with field measurements and a laboratory experiment. We also examined whether top‐down forces affected the red beach distribution by conducting a field survey for crab burrows and density, laboratory feeding trials, and waterbird investigations. The higher sediment accretion rate induced by human activities limited the establishment of new red beaches. The construction of tourism facilities and the frequent presence of tourists reduced the density of waterbirds, which in turn increased the density of crabs, intensifying the top‐down forces such as predators and herbivores that drive the degradation of the coastal red beaches. Our results show that sediment accretion and plant–herbivory changes induced by human activities were likely the two primary ecological processes leading to the degradation of the red beaches. Human activities significantly shaped the abundance and distribution of the red beaches by altering both top‐down and bottom‐up ecological processes. Our findings can help us better understand the dynamics of salt marshes and have implications for the management and restoration of coastal wetlands

Near-Infrared (NIR) Luminescent Homoleptic Lanthanide Salen Complexes Ln(4)(Salen)(4) (Ln = Nd, Yb Or Er)

The series of homoleptic tetranuclear [Ln(4)(L)(2)(HL)(2)(NO3)(2)(OH)(2)]center dot 2(NO3) (Ln = Nd, 1; Ln = Yb, 2; Ln = Er, 3; Ln = Gd, 4) have been self-assembled from the reaction of the Salen-type Schiff-base ligand H2L with Ln(NO3)(3)center dot 6H(2)O (Ln = Nd, Yb, Er or Gd), respectively (H2L: N, N'-bis(salicylidene) cyclohexane-1,2-diamine). The result of their photophysical properties shows that the strong and characteristic NIR luminescence for complexes 1 and 2 with emissive lifetimes in microsecond ranges are observed and the sensitization arises from the excited state (both (LC)-L-1 and (LC)-L-3) of the Salen-type Schiff-base ligand with the flexible linker.National Natural Science Foundation 21173165, 20871098Ministry of Education of China NCET-10-0936Higher Education of China 20116101110003State Key Laboratory of Structure Chemistry 20100014Education Committee Foundation of Shaanxi Province 11JK0588Hong Kong Research Grants Council, P. R. of China HKBU 202407, FRG/06-07/II-16)Hong Kong Research Grants Council, Robert A. Welch Foundation F-816Texas Higher Education Coordinating Board ARP 003658-0010-2006Petroleum Research Fund 47014-AC5Chemistr

A Preliminary Study of the Microbial Resources and Their Biological Activities of the East China Sea

East China Sea is one of the four sea areas in China, which possesses peculiar ecological environment and many kinds of living creatures, especially the microorganisms. We established the East China Sea microorganism library (during 2006–2010) for the first time, which stored about 30000 strains that covered most kinds of the species. In this paper, 395 pure strains of East China Sea microorganism library which belong to 33 different genera were mainly introduced. Sulfitobacter, Halomonas, Bacillus, Pseudoalteromonas, and Idiomarina were the most dominant species. On the large-scale biological activity screening of the 395 strains, 100 strains possess different biological activities based on different screening models, of which 11.4% strains have antibacterial activities, 15.9% have cytotoxicity activities, and 6.1% have antioxidation activities. Besides, the secondary metabolites of 6 strains with strong biological activities were studied systematically; diketopiperazines and macrocyclic lactones are the active secondary metabolites. The species and the biological activity of microorganisms diversity, the abundant structure type of the secondary metabolites, and their bioactivities all indicate that East China Sea is a potent marine microorganisms-derived developing resource for drug discovery

Pedestrian-Aware Supervisory Control System Interactive Optimization of Connected Hybrid Electric Vehicles via Fuzzy Adaptive Cost Map and Bees Algorithm

Electrified vehicles are increasingly being seen as a means of mitigating the pressing concerns of traffic-related pollution. Due to the nature of engine-assisted vehicle exhaust systems, pedestrians in close proximity to these vehicles may experience events where specific emission concentrations are high enough to cause health effects. To minimize pedestrians’ exposure to vehicle emissions and pollutants nearby, we present a pedestrian-aware supervisory control system for connected hybrid electric vehicles by proposing an interactive optimization methodology. This optimization methodology combines a novel fuzzy adaptive cost map and the Bees Algorithm to optimize power-split control parameters. It enables the self-regulation of inter-objective weights of fuel and exhaust emissions based on the real-time pedestrian density information during the optimization process. The evaluation of the vehicle performance by using the proposed methodology is conducted on the realistic trip map involving pedestrian density information collected from the University College Dublin campus. Moreover, two bootstrap sampling techniques and effect of communication quality are both investigated in order to examine the robustness of the improved vehicle system. The results demonstrate that 14.42% mass of exhaust emissions can be reduced for the involved pedestrians, by using the developed fuzzy adaptive cost map

The effect of chemotherapy combined with recombination mutant human tumor necrosis factor on advanced cancer

BACKGROUND: Past studies suggested that tumor necrosis factor (TNF) assisted anti-tumor treatment and intensified the sensitivity of chemotherapy. However its clinical application has been curbed because of its low purity, high dosage, and strong toxicity. This research, through perspective random clinical control experiment, observed the therapeutic effect of the treatment of late malignant tumor through the injection of recombinant mutant human tumor necrosis factor (rmhTNF) combined with general chemotherapy and its adverse reactions. METHODS: 105 patients with advanced malignant tumor were randomly divided into trial group, 69 patients, and control group, 36 patients. Injection of rmhTNF 4 × 10(6)u/m(2 )was given to the trial group, from the 1(st )to 7(th )days, the 11(th )to 17(th )days combined with chemotherapy course. The chemotherapy plan was as follows: CAP for patients with the NSCLC; FAM for patients with gastric cancer; FC for patients with colorectal cancer. One treatment cycle lasted for 21 days and two cycles were scheduled. The control group was given only the same chemotherapy as the trial group. RESULTS: In the trial group there was 1 CR case and 12 PR cases, and the response rate is 13/69 (18.84%); in the control group 1 PR case, the response rate 1/36 (2.78%). The response rate of the trial group was significantly higher than that of the control group (P = 0.022). The response rate for NSCLC in the trial group was 8/17 (47.06%), and 1/6 (16.67%) in the control group. The response rates for gastric cancer and colorectal cancer in the trial groups also were higher than those of the control groups. After the treatment the KPS is 89.00 ± 9.92 in the trial group, and 84.17 ± 8.84 in the control group, with a significant difference between the two groups (P = 0.028). The adverse reactions of rmhTNF injection included: pain in the injection area, chill, hardening and swelling and redness in the injection area, fever, ostealgia and myosalgia, and cold-like symptoms. All these adverse reactions were mild and bearable. CONCLUSIONS: The administration of rmhTNF injection in combination with general chemotherapy is an effective and secure means in treating advanced malignant tumor

Biostratigraphy of the Small Shelly Fossils From the Upper Maidiping Formation (Terreneuvian) at the Fandian Section, Sichuan Province, South China

Small shelly fossils (SSFs) are a useful and critical tool for subdivision and correlation of the Cambrian Terreneuvian stratigraphy. The Maidiping Formation in southern Sichuan is a well-known Terreneuvian lithologic unit with rich SSFs. Here, the upper Maidiping Formation at the Fandian section, an important supplementary section of the classic Maidiping section, is studied for understanding its SSF assemblages and stratigraphic implication. There are 26 genera, 24 species, and 3 undetermined species recovered from the Fandian section, and Watsonella crosbyi was discovered from this section for the first time. Two SSF biozones of the Yangtze Platform, i.e., the possible Paragloborilus subglobosus–Purella squamulosa Assemblage Zone (? Zone II) and the W. crosbyi Assemblage Zone (Zone III), can be recognized. Comparing with the Maidiping section, the Fandian section has a relatively successive SSF biostratigraphy and carbon isotope stratigraphy in the upper Maidiping Formation. The SSF Zone II (?) and Zone III from the Fandian section can be, respectively, correlated to the same zones from the upper Maidiping Formation of the nearby Maidiping section (only Zone III), the upper Zhongyicun and Dahai members of the Zhujiaqing Formation in eastern Yunnan, the top Kuanchuanpu Formation in southern Shaanxi and northern Sichuan, and the beds 4 and 5 (or units 3 and 4) of the Yanjiahe Formation in western Hubei. The almost cosmopolitan distribution and nearly synchronous earliest appearance of W. crosbyi strengthen the applicability of its first appearance data (FAD) to define the base of Cambrian Stage 2 in South China (Xiaotanian) as well as in other continents. The FAD of W. crosbyi just around the onset of the ZHUCE carbon isotope excursion at the Fandian section also further reinforces the utility of the onset of ZHUCE as an auxiliary maker for defining the base of the Xiaotanian in South China

Improved phase-change characteristics of Zn-doped amorphous Sb₇Te₃ films for high-speed and low-power phase change memory

The superior performance of Zn-doped Sb₇Te₃ films might be favorable for the application in phase change memory. It was found that Zn dopants were able to suppress phase separation and form single stable Sb2Te crystal grain, diminish the grain size, and enhance the amorphous thermal stability of Sb₇Te₃ film. Especially, Zn 30.19(Sb₇Te₃)69.81 film has higher crystallization temperature (∼258 °C), larger crystallization activation energy (∼4.15 eV), better data retention (∼170.6 °C for 10 yr), wider band gap (∼0.73 eV), and higher crystalline resistance. The minimum times for crystallization of Zn 30.19(Sb₇Te₃)69.81 were revealed to be as short as ∼10 ns at a given proper laser power of 70 mW.This work was financially supported by the International Science & Technology Cooperation Program of China (Grant No. 2011DFA12040), the National Program on Key Basic Research Project (973 Program) (Grant No. 2012CB722703), the Natural Science Foundation of China (Grant Nos. 61008041 and 60978058), the CAS Special Grant for Postgraduate Research, Innovation and Practice, the Program for Innovative Research Team of Ningbo city (Grant No. 2009B21007), and sponsored by K. C. Wong Magna Fund in Ningbo University