9,288 research outputs found
Ultrafast Relaxation Dynamics of Photoexcited Dirac Fermion in The Three Dimensional Dirac Semimetal Cadmium Arsenide
Three dimensional (3D) Dirac semimetals which can be seen as 3D analogues of
graphene have attracted enormous interests in research recently. In order to
apply these ultrahigh-mobility materials in future electronic/optoelectronic
devices, it is crucial to understand the relaxation dynamics of photoexcited
carriers and their coupling with lattice. In this work, we report ultrafast
transient reflection measurements of the photoexcited carrier dynamics in
cadmium arsenide (Cd3As2), which is one of the most stable Dirac semimetals
that have been confirmed experimentally. By using low energy probe photon of
0.3 eV, we probed the dynamics of the photoexcited carriers that are
Dirac-Fermi-like approaching the Dirac point. We systematically studied the
transient reflection on bulk and nanoplate samples that have different doping
intensities by tuning the probe wavelength, pump power and lattice temperature,
and find that the dynamical evolution of carrier distributions can be retrieved
qualitatively by using a two-temperature model. This result is very similar to
that of graphene, but the carrier cooling through the optical phonon couplings
is slower and lasts over larger electron temperature range because the optical
phonon energies in Cd3As2 are much lower than those in graphene
Impurity resonance states in electron-doped high T_c superconductors
Two scenarios, i.e., the anisotropic s-wave pairing (the s-wave scenario) and
the d-wave pairing coexisting with antiferromagnetism (the coexisting scenario)
have been introduced to understand some of seemingly s-wave like behaviors in
electron doped cuprates. We considered the electronic structure in the presence
of a nonmagnetic impurity in the coexistence scenario. We found that even if
the AF order opens a full gap in quasi-particle excitation spectra, the mid-gap
resonant peaks in local density of states (LDoS) around an impurity can still
be observed in the presence of a d-wave pairing gap. The features of the
impurity states in the coexisting phase are markedly different from the pure AF
or pure d-wave pairing phases, showing the unique role of the coexisting AF and
d-wave pairing orders. On the other hand, it is known that in the pure s-wave
case no mid-gap states can be induced by a nonmagnetic impurity. Therefore we
proposed that the response to a nonmagnetic impurity can be used to
differentiate the two scenarios.Comment: 5 pages, two-column revtex4, 5 figures, author list correcte
A Transmissive X-ray Polarimeter Design For Hard X-ray Focusing Telescopes
The X-ray Timing and Polarization (XTP) is a mission concept for a future
space borne X-ray observatory and is currently selected for early phase study.
We present a new design of X-ray polarimeter based on the time projection gas
chamber. The polarimeter, placed above the focal plane, has an additional rear
window that allows hard X-rays to penetrate (a transmission of nearly 80% at 6
keV) through it and reach the detector on the focal plane. Such a design is to
compensate the low detection efficiency of gas detectors, at a low cost of
sensitivity, and can maximize the science return of multilayer hard X-ray
telescopes without the risk of moving focal plane instruments. The sensitivity
in terms of minimum detectable polarization, based on current instrument
configuration, is expected to be 3% for a 1mCrab source given an observing time
of 10^5 s. We present preliminary test results, including photoelectron tracks
and modulation curves, using a test chamber and polarized X-ray sources in the
lab
Effect of sevoflurane post-conditioning on apoptosis and the expressions of Bcl-2 and Bax in lung tissue of cardiopulmonary bypass dogs
Purpose: To investigate the effects of sevoflurane post-conditioning on the expressions of Bcl-2 and Bax in lung tissues of cardiopulmonary bypass (CPB) dogs.
Methods: Twelve healthy hybrid mongrels were divided into control (C) and sevoflurane postconditioning (S) groups. All dogs were subjected to thoracotomy in order to establish CPB. Ischemiareperfusion was conducted in the left lung of both groups. Thereafter, sevoflurane post-conditioning was given to group S. Femoral artery blood specimens were obtained prior to CPB (T1), as the left pulmonary artery was opened (T2), and 2 h after CPB (T3), for blood gas analysis. Respiration index (RI), oxygenation index (OI), and dynamic lung compliance (Cd) were calculated.
Results: When T1 was compared with T2 and T3, their OI and Cd were significantly decreased in both groups, while RI showed the opposite trend (p < 0.05). Values of OI and Cd at T3 in group S were increased significantly, relative to group C, while RI decreased (p < 0.05). There were less lung tissue inflammation and structural disorder at T3 in Group S than in group C. Protein expressions and positive integral of Bcl-2 and Bax, and apoptosis at T2 and T3 in dog lung tissues of both groups were higher than those at T1 (p < 0.05).
Conclusion: Post-conditioning with sevoflurane is lung-protective in CPB dogs. The underlying mechanism may be based on the promotion of Bcl-2 expression and inhibition of Bax expression, thereby reducing apoptosis in dog lung tissue. Further investigations to determine its suitability for clinical applications in humans are, however, required.
Keywords: Sevoflurane; Cardiopulmonary bypass; Bcl-2, Bax; Apoptosis; Pulmonary ischemiareperfusion injur
Crystal structure of tubulin folding cofactor A from Arabidopsis thaliana and its β-tubulin binding characterization
AbstractMicrotubules are composed of polymerized α/β-tubulin heterodimers. Biogenesis of assembly-competent tubulin dimers is a complex multistep process that requires sequential actions of distinct molecular chaperones and cofactors. Tubulin folding cofactor A (TFCA), which captures β-tubulin during the folding pathway, has been identified in many organisms. Here, we report the crystal structure of Arabidopsis thaliana TFC A (KIESEL, KIS), which forms a monomeric three-helix bundle. The functional binding analysis demonstrated that KIS interacts with β-tubulin in plant. Furthermore, mutagenesis studies indicated that the α-helical regions of KIS participate in β-tubulin binding. Unlike the budding yeast TFC A, the two loop regions of KIS are not required for this interaction suggesting a distinct binding mechanism of TFC A to β-tubulin in plants.Structured summaryMINT-7968902, MINT-7968915, MINT-7968951, MINT-7968966: KIS (uniprotkb:O04350) physically interacts (MI:0915) with Tub9 (uniprotkb:P29517) by anti tag coimmunoprecipitation (MI:0007)MINT-7968928: KIS (uniprotkb:O04350) and Tub9 (uniprotkb:P29517) physically interact (MI:0915) by bimolecular fluorescence complementation (MI:0809
Electrons dynamics control by shaping femtosecond laser pulses in micro/nanofabrication: modeling, method, measurement and application
During femtosecond laser fabrication, photons are mainly absorbed by electrons, and the subsequent energy transfer from electrons to ions is of picosecond order. Hence, lattice motion is negligible within the femtosecond pulse duration, whereas femtosecond photon-electron interactions dominate the entire fabrication process. Therefore, femtosecond laser fabrication must be improved by controlling localized transient electron dynamics, which poses a challenge for measuring and controlling at the electron level during fabrication processes. Pump-probe spectroscopy presents a viable solution, which can be used to observe electron dynamics during a chemical reaction. In fact, femtosecond pulse durations are shorter than many physical/chemical characteristic times, which permits manipulating, adjusting, or interfering with electron dynamics. Hence, we proposed to control localized transient electron dynamics by temporally or spatially shaping femtosecond pulses, and further to modify localized transient materials properties, and then to adjust material phase change, and eventually to implement a novel fabrication method. This review covers our progresses over the past decade regarding electrons dynamics control (EDC) by shaping femtosecond laser pulses in micro/nanomanufacturing: (1) Theoretical models were developed to prove EDC feasibility and reveal its mechanisms; (2) on the basis of the theoretical predictions, many experiments are conducted to validate our EDC-based femtosecond laser fabrication method. Seven examples are reported, which proves that the proposed method can significantly improve fabrication precision, quality, throughput and repeatability and effectively control micro/nanoscale structures; (3) a multiscale measurement system was proposed and developed to study the fundamentals of EDC from the femtosecond scale to the nanosecond scale and to the millisecond scale; and (4) As an example of practical applications, our method was employed to fabricate some key structures in one of the 16 Chinese National S&T Major Projects, for which electron dynamics were measured using our multiscale measurement system
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