148 research outputs found
Order-Preserving Abstractive Summarization for Spoken Content Based on Connectionist Temporal Classification
Connectionist temporal classification (CTC) is a powerful approach for
sequence-to-sequence learning, and has been popularly used in speech
recognition. The central ideas of CTC include adding a label "blank" during
training. With this mechanism, CTC eliminates the need of segment alignment,
and hence has been applied to various sequence-to-sequence learning problems.
In this work, we applied CTC to abstractive summarization for spoken content.
The "blank" in this case implies the corresponding input data are less
important or noisy; thus it can be ignored. This approach was shown to
outperform the existing methods in term of ROUGE scores over Chinese Gigaword
and MATBN corpora. This approach also has the nice property that the ordering
of words or characters in the input documents can be better preserved in the
generated summaries.Comment: Accepted by Interspeech 201
Study of \Lambda - \Lambdabar Oscillation in quantum coherent \Lambda\Lambdabar state by using J/\psi \to \Lambda \bar{\Lambda}$ decay
We discuss the possibility of searching for the \Lam - \Lamb oscillations
for coherent \Lam\Lamb production in the J/\psi \to \Lam \Lamb decay
process. The sensitivity of measurement of \Lam -\Lamb oscillation in the
external field at BES-III experiment is considered. These considerations
indicate an alternative way to probe the amplitude in addition to
neutron oscillation experiments. Both coherent and time-dependent information
can be used to extract the \Lam-\Lamb oscillation parameter. With one year's
luminosity at BES-III, we can set an upper limit of \delta m_{\Lam \Lamb} <
10^{-15} MeV at 90% confidence level, corresponding to about s of
\Lam-\Lamb oscillation time.Comment: 4 pages, no figure, minor corrections to improve grammar, published
in Phys.Rev.D as Rapid Communication
DIALGEN: Collaborative Human-LM Generated Dialogues for Improved Understanding of Human-Human Conversations
Applications that could benefit from automatic understanding of human-human
conversations often come with challenges associated with private information in
real-world data such as call center or clinical conversations. Working with
protected data also increases costs of annotation, which limits technology
development. To address these challenges, we propose DIALGEN, a
human-in-the-loop semi-automated dialogue generation framework. DIALGEN uses a
language model (ChatGPT) that can follow schema and style specifications to
produce fluent conversational text, generating a complex conversation through
iteratively generating subdialogues and using human feedback to correct
inconsistencies or redirect the flow. In experiments on structured
summarization of agent-client information gathering calls, framed as dialogue
state tracking, we show that DIALGEN data enables significant improvement in
model performance
Bcp1 is the nuclear chaperone of Rpl23 in Saccharomyces cerevisiae
Eukaryotic ribosomes are composed of rRNAs and ribosomal proteins. Ribosomal proteins are translated in the cytoplasm and imported into the nucleus for assembly with the rRNAs. It has been shown that chaperones or karyopherins responsible for import can maintain the stability of ribosomal proteins by neutralizing unfavorable positive charges and thus facilitate their transports. Among 79 ribosomal proteins in yeast, only a few are identified with specific chaperones. Besides the classic role in maintaining protein stability, chaperones have additional roles in transport, chaperoning the assembly site, and dissociation of ribosomal proteins from karyopherins. Bcp1 has been shown to be necessary for the export of Mss4, a phosphatidylinositol 4-phosphate 5-kinase, and required for ribosome biogenesis. However, its specific function in ribosome biogenesis has not been described. Here, we show that Bcp1 dissociates Rpl23 from the karyopherins and associates with Rpl23 afterward. Loss of Bcp1 causes instability of Rpl23 and deficiency of 60S subunits. In summary, Bcp1 is a novel 60S biogenesis factor via chaperoning Rpl23 in the nucleus
Comparative and functional genomics reveals genetic diversity and determinants of host specificity among reference strains and a large collection of Chinese isolates of the phytopathogen Xanthomonas campestris pv. campestris
Construction of a microarray based on the genome of Xanthomonas campestris pv.campestris (Xcc), and its use to analyse 18 other virulent Xcc strains, revealed insights into the genetic diversity and determinants of host specificity of Xcc strains
The small molecule raptinal can simultaneously induce apoptosis and inhibit PANX1 activity
Discovery of new small molecules that can activate distinct programmed cell death pathway is of significant interest as a research tool and for the development of novel therapeutics for pathological conditions such as cancer and infectious diseases. The small molecule raptinal was discovered as a pro-apoptotic compound that can rapidly trigger apoptosis by promoting the release of cytochrome c from the mitochondria and subsequently activating the intrinsic apoptotic pathway. As raptinal is very effective at inducing apoptosis in a variety of different cell types in vitro and in vivo, it has been used in many studies investigating cell death as well as the clearance of dying cells. While examining raptinal as an apoptosis inducer, we unexpectedly identified that in addition to its pro-apoptotic activities, raptinal can also inhibit the activity of caspase-activated Pannexin 1 (PANX1), a ubiquitously expressed transmembrane channel that regulates many cell death-associated processes. By implementing numerous biochemical, cell biological and electrophysiological approaches, we discovered that raptinal can simultaneously induce apoptosis and inhibit PANX1 activity. Surprisingly, raptinal was found to inhibit cleavage-activated PANX1 via a mechanism distinct to other well-described PANX1 inhibitors such as carbenoxolone and trovafloxacin. Furthermore, raptinal also interfered with PANX1-regulated apoptotic processes including the release of the 'find-me' signal ATP, the formation of apoptotic cell-derived extracellular vesicles, as well as NLRP3 inflammasome activation. Taken together, these data identify raptinal as the first compound that can simultaneously induce apoptosis and inhibit PANX1 channels. This has broad implications for the use of raptinal in cell death studies as well as in the development new PANX1 inhibitors
The LAMOST Survey of Background Quasars in the Vicinity of the Andromeda and Triangulum Galaxies -- II. Results from the Commissioning Observations and the Pilot Surveys
We present new quasars discovered in the vicinity of the Andromeda and
Triangulum galaxies with the LAMOST during the 2010 and 2011 observational
seasons. Quasar candidates are selected based on the available SDSS, KPNO 4 m
telescope, XSTPS optical, and WISE near infrared photometric data. We present
509 new quasars discovered in a stripe of ~135 sq. deg from M31 to M33 along
the Giant Stellar Stream in the 2011 pilot survey datasets, and also 17 new
quasars discovered in an area of ~100 sq. deg that covers the central region
and the southeastern halo of M31 in the 2010 commissioning datasets. These 526
new quasars have i magnitudes ranging from 15.5 to 20.0, redshifts from 0.1 to
3.2. They represent a significant increase of the number of identified quasars
in the vicinity of M31 and M33. There are now 26, 62 and 139 known quasars in
this region of the sky with i magnitudes brighter than 17.0, 17.5 and 18.0
respectively, of which 5, 20 and 75 are newly-discovered. These bright quasars
provide an invaluable collection with which to probe the kinematics and
chemistry of the ISM/IGM in the Local Group of galaxies. A total of 93 quasars
are now known with locations within 2.5 deg of M31, of which 73 are newly
discovered. Tens of quasars are now known to be located behind the Giant
Stellar Stream, and hundreds behind the extended halo and its associated
substructures of M31. The much enlarged sample of known quasars in the vicinity
of M31 and M33 can potentially be utilized to construct a perfect astrometric
reference frame to measure the minute PMs of M31 and M33, along with the PMs of
substructures associated with the Local Group of galaxies. Those PMs are some
of the most fundamental properties of the Local Group.Comment: 26 pages, 6 figures, AJ accepte
Proton-Boron Fusion Yield Increased by Orders of Magnitude with Foam Targets
A novel intense beam-driven scheme for high yield of the tri-alpha reaction
11B(p,{\alpha})2{\alpha} was investigated. We used a foam target made of
cellulose triacetate (TAC, C_9H_{16}O_8) doped with boron. It was then heated
volumetrically by soft X-ray radiation from a laser heated hohlraum and turned
into a homogenous, and long living plasma. We employed a picosecond laser pulse
to generate a high-intensity energetic proton beam via the well-known Target
Normal Sheath Acceleration (TNSA) mechanism. We observed up to 10^{10}/sr
{\alpha} particles per laser shot. This constitutes presently the highest yield
value normalized to the laser energy on target. The measured fusion yield per
proton exceeds the classical expectation of beam-target reactions by up to four
orders of magnitude under high proton intensities. This enhancement is
attributed to the strong electric fields and nonequilibrium thermonuclear
fusion reactions as a result of the new method. Our approach shows
opportunities to pursue ignition of aneutronic fusion
Laboratory observation of ion acceleration via reflection off laser-produced magnetized collisionless shocks
Fermi acceleration by collisionless shocks is believed to be the primary
mechanism to produce high energy charged particles in the Universe,where
charged particles gain energy successively from multiple reflections off the
shock front.Here,we present the first direct experimental evidence of ion
energization from reflection off a supercritical quasi perpendicular
collisionless shock,an essential component of Fermi acceleration in a laser
produced magnetized plasma. We observed a quasi monoenergetic ion beam with 2,4
times the shock velocity in the upstream flow using time of flight method. Our
related kinetic simulations reproduced the energy gain and showed that these
ions were first reflected and then accelerated mainly by the motional electric
field associated with the shock. This mechanism can also explain the quasi
monoenergetic fast ion component observed in the Earth's bow shock
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