DIAGNOSTICS OF LOCAL MAGNETIC FIELDS IN SOLAR FLARES USING FeI 5383 AND MgI 5528 LINES

Main  purpose of  the  present work is  to estimate upper limit of the local magnetic field strength in solar flares  using spectral lines FeI  5383  and MgI  5528. These lines like FeI 5233  have  low  Landé  factors  (1.12 and 1.00,  respectively) and  relatively  large spectral width (0.2–0.3 Ǻ). On this account, even in a case of very strong fields (3-4 kG) they must show the simple picture of the Zeeman splitting, with parallel to each other the bisectors of profiles I+V and I – V.  In  actual  fact,  another picture was found  for  nine flares: bisectors  of  these  lines have maximums of splitting on certain distances from line center, what must not be in the homogeneous magnetic field. In particular, both lines have peak of bisector splitting on distance 150–170 mǺ  from  line center.  If we assume  the Zeeman nature of named peculiarities then necessary fields are11.2 kGfor FeI 5383 and 10.5-11.2 kGfor MgI 5528. Likely, this agreement of field values is a new argument to reality of such very strong magnetic fields in flares.  Main purpose of the present work is to estimate upper limit of the local magnetic field strength in solar flares using spectral lines FeI 5383 and MgI 5528. These lines like FeI 5233 have low Landé factors (1.12 and 1.00, respectively) and relatively large spectral width (0.2–0.3 Ǻ). On this account, even in a case of very strong fields (3-4 kG) they must show the simple picture of the Zeeman splitting, with parallel to each other the bisectors of profiles I+V and I – V. In actual fact, another picture was found for nine flares: bisectors of these lines have maximums of splitting on certain distances from line center, what must not be in the homogeneous magnetic field. In particular, both lines have peak of bisector splitting on distance 150–170 mǺ from line center. If we assume the Zeeman nature of named peculiarities then necessary fields are 11.2 kG for FeI 5383 and 10.5-11.2 kG for MgI 5528. Likely, this agreement of field values is a new argument to reality of such very strong magnetic fields in flares

Proteolysis Inhibitor E-Aminocaproic Acid as Effective Drug for Prevention and Treatment of Influenza, Other Acute Respiratory Viral Infections and their Bacterial Complications

We have established the efficacy of proteolysis inhibitor (PI) aminocaproic acid (ACA) in viral infections as a result of its impact on the etiological factor and pathogenesis of the infection. The Ministry of Health of Ukraine on the basis of our studies and clinical trials allowed using ACA for prophylaxis and treatment of influenza and other acute respiratory viral infections (ARVI). Including ACA to therapeutic complex for the treatment of influenza and other ARVI in children and neonates led to a decrease of the duration of symptoms of intoxication, catarrhal phenomena, and fever as well as to a decrease of the number of complications. The prevention effectiveness of ACA has also been established. The obtained results allow to recommend the use of ACA for the efficient prophylaxis of ARVIs and pneumonia in organized collectives in the period of increased incidences of these infections. Our research has shown that the combined use of drugs with different mechanisms of action - PI ACA and neuraminidase inhibitor Tamiflu - causes a synergistic effect. We also studied the antibacterial action of ACA on S. aureus strains with different sensitivity to antibiotics. ACA inhibits all these strains, and the combined use of ACA with antibiotics magnifies the antibacterial effect

Synthesis and antioxidant and anti-influenza activity of aminomethanesulfonic acids

Aminomethanesulfonic acid (I) and its N-methyl- (II), N-(2-hydroxy)ethyl- (III), N-(tert-butyl)- (IV), N-benzyl- (V), and 4-(N-phenylaminomethyl)phenyl- (VI) derivatives (V and VI not previously reported) were synthesized and characterized by elemental analysis and IR and mass spectroscopy. The in vitro antioxidant activities of aminomethanesulfonic acids I-VI were found to be comparatively weak. Compounds IV and V suppressed statistically significantly reproduction of influenza virus strains A/Hong Kong/1/68 (H3N2) and A/PR/8/34 (H1N1) in chorioallantoic membrane tissue culture

Synthesis, antioxidant and anti-influenza activity of aminomethanesulphonic acids

Синтезированы аминометансульфокислота, а также ее N-метил-(II), N-(2-гидрокси) этил-(III), N-(трет-бутил)-(IV), N-бензил-(V) и 4-(N-фениламинометил) фенил-(VI) производные (V и VI ранее не описаны), которые охарактеризованы методами элементного анализа, ИК-и масс-спектроскопии. Оценена антиоксидантная активность I–VI in vitro, отмечены сравнительно слабые антиоксидантные свойства аминометансульфокислот. Показано, что соединения IV и V статистически значимо подавляют репродукцию вируса гриппа штаммов А/Гонконг/1/68 (H3N2) и А/PR/8/34 (H1N1) на культуре ткани хорион-аллантоисных оболочек.Aminomethanesulphonic acid (I), and its N-methyl (II), N-(2-hydroxy)ethyl (III), N-tert-butyl (IV), N-benzyl (V, and 4-(N-phenylaminomethyl)phenyl (VI) derivatives have been synthesized (V and VI were not previously described) and characterized by elemental analysis, IR, and mass spectroscopy. In vitro investigation of the antioxidant activity of I – VI showed relatively weak antioxidant properties of aminomethanesulphonic acids. It was found that IV and V exhibited statistically significant suppression of A/Hong Kong/1/68 (H3N2) and A/PR/8/34 (H1N1) strains reproduction in tissue culture of chorio-allantoic membranes