Télescope comprenant un miroir principal sphérique, à grand champ de vision et à haute résolution optique

Télescope à grand champ de vision, haute résolution optique et continuité du champ de vision comprenant un miroir primaire sphérique, (M1), caractérisé par le fait a) que ledit télescope est équipé d'un système de répartition du champ de vision, b) que ledit système de répartition du champ de vision est placé à proximité du point focal (M1f) du miroir primaire et est constitué d'un miroir (M2) secondaire constitué de surfaces réfléchissantes planes n, (fc1-16) c) que lesdites surfaces réfléchissantes planes n sont contiguës l'une à l'autre et forment un réflecteur continu à facettes prismatiques multiples, de manière à obtenir la continuité du champ de vision sur l'ensemble du champ, d) que lesdites surfaces réfléchissantes planes n sont suivies par un nombre correspondant de correcteurs (C1-n) et de caméras optiques (Rc1 -n) qui forment des portions n d'une image dans des plans focaux n distincts (fp1-n) e) que, sur chaque plan focal n-ième, est positionné un élément collecteur et d'enregistrement

Note Illustrative della Carta geologica d'Italia alla scala 1:50.000 Foglio 204 Portomaggiore. Servizio Geologico d'Italia.

Note illustrative redatte per il Foglio geologico n. 204 Portomaggiore della Carta Geologica d'Italia alla scala 1:50.000. 98 pp

Sexual Functioning and Opioid Maintenance Treatment in Women. Results From a Large Multicentre Study

Opioid maintenance treatment (OMT) is the most widespread therapy for both females and males opioid addicts. While many studies have evaluated the OMT impact on men’s sexuality, the data collected about the change in women’s sexual functioning is still limited despite the fact that it is now well-known that opioids - both endogenous and exogenous - affect the endocrine system and play an important role in sexual functioning. The present study aims to determine how OMT with buprenorphine (BUP) or methadone (MTD) affects sexual health in women; examining also any possible emerging correlation between sexual dysfunction (SD), type of opioid and patients’ mental health. This multi-center study case recruited 258 female volunteers attending Italian public Addiction Outpatients Centers that were stabilized with OMT for at least 3 months. SD was assessed with the Arizona Sexual Experience Scale. The twelve-item General Health Questionnaire was used to assess participants’ mental health conditions. The results show that 56.6% of women receiving OMT for at least 3 months presented SD without significant differences between MTD e BUP groups. The majority of the subjects with SD have a poorer quality of intimate relationships and worse mental health than the average. To the best of our knowledge, the present study is the largest report on the presence of SDs in women as a side effects of MTD and BUP used in OMT. Since SDs cause difficulties in intimate relationships, lower patients’ quality of life and interfere with OMT beneficial outcomes, we recommend that women undertaking an opioid therapy have routine screening for SD and we highlight the importance to better examine opioid-endocrine interactions in future studies in order to provide alternative potential treatments such as the choice of opioid, opioid dose reduction and hormone supplementation

Intravenous misuse of Methadone, Buprenorphine and Buprenorphine-Naloxone in patients under opioid maintenance treatment: a cross-sectional multicentre study

BACKGROUND: The act of intravenous misuse is common in patients under opioid maintenance treatment (OMT), but information on associated factors is still limited. OBJECTIVES: To explore factors associated with (a) intravenous OMT misuse, (b) repeated misuse, (c) emergency room (ER) admission, (d) misuse of different OMT types and (e) concurrent benzodiazepine misuse. METHODS: We recruited 3,620 patients in 27 addiction units in Italy and collected data on the self-reported rate of intravenous injection of methadone (MET), buprenorphine (BUP), BUP-naloxone (NLX), OMT dosage and type, experience of and reason for misuse, concurrent intravenous benzodiazepine misuse, pattern of -misuse in relation to admission to the addiction unit and ER -admissions because of misuse. According to inclusion/exclusion criteria, 2,585 patients were included. RESULTS: Intravenous misuse of OMT substances was found in 28% of patients with no difference between OMT types and was associated with gender, age, type of previous opioid abuse and intravenous benzodiazepine misuse. Repeated OMT misuse was reported by 20% (i.e., 71% of misusers) of patients and was associated with positive OMT misuse experience and intravenous benzodiazepine misuse. Admission to the ER because of misuse complications was reported by 34% of patients, this outcome being associated with gender, employment, type of previous opioid abuse and intravenous benzodiazepine misuse. OMT dosage was lower than the recommended maintenance dosage. CONCLUSIONS: We offered new information on factors associated with intravenous OMT misuse, repeated misuse and ER admission in Italian patients under OMT. Our data indicate that BUP-NLX misuse is not different from that of BUP or MET. Choosing the more expensive BUP-NLX over MET will likely not lead to the expected reduction of the risk of injection misuse of the OMT. Instead of prescribing new and expensive OMT formulations, addiction unit physicians and medical personnel should better focus on patient's features that are associated with a higher likelihood of misuse. Care should be paid to concurrent benzodiazepine and OMT misuse

Association between adult attention deficit/hyperactivity disorder and intravenous misuse of opioid and benzodiazepine in patients under opioid maintenance treatment: a cross-sectional multicentre study

BACKGROUND: Intravenous misuse and attention-deficit/hyperactivity disorder (ADHD) are common in patients under opioid maintenance treatment (OMT), who often misuse benzodiazepine (BZD). OBJECTIVES: To explore the rate of adult ADHD among patients under OMT in Italy and whether screening positive for adult ADHD is associated with OMT and BZD misuse and emergency room (ER) admission because of misuse. METHODS: We recruited 1,649 patients from 27 addiction units (AUs) in Italy and collected data on the self-reported rate of OMT intravenous misuse (prevalence, repeated misuse, main reason, temporal pattern in relation to AU access, experience), concurrent intravenous and intranasal BZD misuse (prevalence, type of misused BZD), ADHD and ER admissions because of misuse complications. RESULTS: Screening positive for adult ADHD was found in 11.2% patients (ADHD+), with a significant gender difference (women: 15.3%, men: 10.3%). OMT misuse was reported by 24.4 and 18.5% patients during lifetime and in the previous 6 months respectively. BZD misuse was reported by 20.0 and 8.6% patients for intravenous and intranasal route respectively. Misuse was significantly more common in ADHD+ (OMT 27.4-33.1%, BZD 14.5-31.5%) than ADHD- group (OMT 17.4-23.3%, BZD 7.9-18.3%). The multivariate logistic regression model showed positive screening for ADHD to be significantly associated with intravenous OMT misuse in the previous 6 months, and intravenous/intranasal BZD misuse, independently of age, gender and route of previous heroin administration. CONCLUSIONS: Screening positive for adult ADHD was associated with OMT and BZD misuse. AU physicians and medical personnel should focus on OMT patient's features that are associated with a higher likelihood of misuse, in particular ADHD

An Innovative Compact System to Measure Skiing Ground Reaction Forces and Flexural Angles of Alpine and Touring Ski Boots

Skiing is a popular winter activity spanning various subdisciplines. Key hardware are ski boots, bindings, and skis, which are designed to withstand loads generated during skiing. Obtaining service forces and moments has always been challenging to researchers in the past. The goal of the present study is to develop and test a lightweight and compact measurement system to obtain the Ground Reaction Forces and the kinematics for ski touring and alpine ski. To do so, we adapted two six-axis load cells to fit into ski touring and alpine skis adding 20 mm height and 500 g weight to the original ski. To measure kinematics, we created custom angular sensors from rotary potentiometers. The system was tested indoors using a force platform and motion capture system before a first set of field tests in which the sensors were used to measure ski touring and alpine skis kinetics and kinematics. Validation trials showed maximum errors of 10% for kinetics and 5% for kinematics. Field tests showed data in agreement with previous findings on the topic. The results of this study show the possibility of using our system to study biomechanics and equipment performances for ski touring, alpine skiing, and possibly other disciplines

Conduction disorders after aortic valve replacement with rapid-deployment bioprostheses: early occurrence and one-year evolution

Rapid-deployment bioprostheses represent one of the newest aortic valve substitutes introduced into clinical practice. The aim of this retrospective single-center study was to evaluate the occurrence of conduction disorders (CDs) after rapid-deployment aortic valve implantation at discharge and at 1-year follow-up, and to identify risk factors for CDs and permanent pacemaker implantation (PPI)

Attivazione di un Sistema Epidemiologico di Sorveglianza (SEI) nella ULSS 18 della Regione Veneto.

Il monitoraggio delle malattie in una dimensione di popolazione sta diventando sempre pi\uf9 una necessit\ue0 dei Sistemi Sanitari moderni per fronteggiare adeguatamente i complessi compiti derivanti dall\u2019invecchiamento della popolazione e dalle emergenze sanitarie. In questo ambito l\u2019utilizzo, a scopo epidemiologico, degli archivi sanitari elettronici esistenti presso le ULSS pu\uf2 rappresentare un nuovo e potente strumento integrato di sorveglianza dello stato di salute della popolazione. Vengono qui presentati i risultati preliminari di un progetto di attivazione di un SEI nell\u2019ULSS 18 di Rovigo nella quale sono stati estratti dagli archivi i dati riguardanti i ricoveri ospedalieri (SDO) comprendenti i day-hospital e la mobilit\ue0 passiva, i certificati di morte (CM), i referti anatomopatologici (AP) e le prescrizioni farmaceutiche (PF). Nel periodo 1995-2006 sono state estratte e sottoposte a verifiche di qualit\ue0 984944 AP, nel periodo 1996-2006 24353 CM, nel periodo 1997-2006 13166897 PF e nel periodo 1999-2006 282902 SDO (esclusa la mobilit\ue0 passiva), per una popolazione media annuale di 233891 assistiti nel periodo 1999-2006. Attraverso un record- linkage deterministico a cascata verranno agganciate tutte le fonti informative all\u2019anagrafe sanitaria per la costruzione di un sistema di monitoraggio delle malattie nella popolazione generale