A systematic review and meta-analysis of the diagnostic accuracy of the Phototest for cognitive impairment and dementia

The recently developed Phototest is a simple, easy and very brief test for detecting cognitive impairment or dementia. Objective: To evaluate the diagnostic accuracy of the Phototest for detecting cognitive impairment or dementia. METHODS: We used a manually created database to search for studies evaluating the Phototest diagnostic yield and performed an initial meta-analysis to determine sensitivity (Sn) and specificity (Sp) of diagnostic parameters. We also performed a second meta-analysis of individual participant data. RESULTS: In total, 6 studies were included in the meta-analysis. For dementia, Sn was 0.85 (95% CI, 0.82-0.88) and Sp 0.87 (95% CI, 0.85-0.99); for cognitive impairment, Sn was 0.80 (95% CI, 0.77-0.92) and Sp 0.88 (95% CI, 0.86-0.90). In the individual data meta-analysis, 1565 subjects were included, where best cut-off points for dementia and for cognitive impairment were 26/27 (Sn=0.89 (95% CI 0.85-0.91), Sp=0.84 (95% CI, 0.82-0.91)) and 28/29 (Sn=0.79 (95% CI, 0.76-0.81), Sp=0.88 (95% CI, 0.86-0.90)), respectively. CONCLUSION: Phototest has good diagnostic accuracy for dementia and cognitive impairment. It is brief, simple and can be used in illiterate persons. This makes it suitable for use in primary care settings and/or in subjects with low educational level.Phototest é um teste simples, fácil e muito rápido para detecção de comprometimento cognitivo e demência recentemente desenvolvido. Objetivo: Avaliar a acurácia diagnostica do Phototest para detecção de comprometimento cognitivo e demência. MÉTODOS: Nós usamos um banco de dados manualmente criado para estudos que avaliassem a capacidade diagnóstica do Phototest e realizamos uma meta-análise para determinar a sensibilidade (Sn) e especificidade (Ep) dos parâmetros diagnósticos. Nós também realizamos uma segunda meta-análise dos dados individuais dos participantes. RESULTADOS: Um total de seis estudos foram incluídos na meta-análise. Para demência a Sn foi 0.85 (95% CI, 0,82-0,88) e Ep 0,87 (95% CI, 0,85-0,99); para comprometimento cognitivo a Sn foi 0,80 (95% CI, 0,77-0,92) e Sp 0,88 (95% CI, 0,86-0,90). Na meta-análise de dados individuais, 1565 foram incluídos, os melhores escores de corte para demência e para comprometimento cognitivo foram 26/27 (Sn=0,89 (95% CI 0,85-0,91), Ep=0,84 (95% CI, 0,82-0,91)) e 28/29 (Sn=0,79 (95% CI, 0,76-0,81), Ep=0,88 (95% CI, 0,86-0,90)), respectivamente. CONCLUSÃO: Photest tem boa acurácia diagnostica para demência e comprometimento cognitivo. É breve, simples e pode ser usado em pessoas analfabetas. Tornando-o apropriado para o uso em cuidados primários e/ou sujeitos com baixo nível educacional.Fil: Carnero Pardo, Cristobal. Hospital Universitario Virgen de Las Nieves; España. Fidyan Neurocenter; EspañaFil: Lopez Alcalde Samuel. Fidyan Neurocenter; España. Hospital Universitario Virgen de Las Nieves; EspañaFil: Allegri, Ricardo Francisco. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación para la Lucha Contra las Enfermedades Neurológicas de la Infancia. Instituto de Investigaciones Neurológicas ; ArgentinaFil: Russo, María Julieta. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación para la Lucha Contra las Enfermedades Neurológicas de la Infancia. Instituto de Investigaciones Neurológicas ; Argentin

The Graphicahedron

The paper describes a construction of abstract polytopes from Cayley graphs of symmetric groups. Given any connected graph G with p vertices and q edges, we associate with G a Cayley graph of the symmetric group S_p and then construct a vertex-transitive simple polytope of rank q, called the graphicahedron, whose 1-skeleton (edge graph) is the Cayley graph. The graphicahedron of a graph G is a generalization of the well-known permutahedron; the latter is obtained when the graph is a path. We also discuss symmetry properties of the graphicahedron and determine its structure when G is small.Comment: 21 pages (European Journal of Combinatorics, to appear

La calidad del servicio y su relación con la satisfacción de los clientes en la empresa Electrónica San Miguel SAC, Lima, 2023

Presente investigación se desarrolló teniendo el objetivo de verificar la relación entre calidad de servicio y satisfacción de clientes en la empresa Electrónica San Miguel SAC, Lima, 2023. Para lo cual se tuvo en consideración información obtenida de libros, artículos de revistas confiable, para dar sustentación válida a la investigación. El método ha sido aplicado al considerar la teoría de las variables, el enfoque ha sido cuantitativo, diseño fue no experimental. Muestra sesenta (60) clientes empresa Electrónica San Miguel SAC. Al obtener la data de las encuestas, estas fueron ingresadas en el programa de IBM spssv26 para obtener los resultados descriptivos e inferenciales, con finalidad de obtener el resultado de la prueba no paramétrica que tuvo un valor de significancia menor a 0,05 y los valores del Rho Spearman con coeficiente 0,746 , significa que existe una correlación positiva considerable entre variables planteadas en la investigación, concluyendo que mejor calidad en el servicio brindado en el servicio técnico en la reparación de equipos se incrementa la satisfacción de su clientes.This investigation was developed with the objective of verifying the relationship between quality of service and customer satisfaction in the company Electrónica San Miguel SAC, Lima, 2023. For which information obtained from books, articles from reliable magazines were taken into consideration, to give valid support for the research. The method has been applied when considering the theory of the variables, the approach has been quantitative, the design was non-experimental. It shows sixty (60) clients of the company Electrónica San Miguel SAC. When obtaining the data from the surveys, they were entered into the IBM spssv26 program to obtain the descriptive and inferential results, in order to obtain the result of the non-parametric test that had a significance value of less than 0.05 and the values of Rho Spearman with a coefficient of 0.746, means that there is a considerable positive correlation between variables raised in the investigation, concluding that better quality in the service provided in the technical service in the repair of equipment increases the satisfaction of its clients

Fast Synthetic Dataset for Kitchen Object Segmentation in Deep Learning

Object recognition has been widely investigated in computer vision for many years. Currently, this process is carried out through neural networks, but there are very few public datasets available with mask and class labels of the objects for the training process in usual applications. In this paper, we address the problem of fast generation of synthetic datasets to train neural models because creating a handcraft labeled dataset with object segmentation is a very tedious and time-consuming task. We propose an efficient method to generate a synthetic labeled dataset that adequately combines background images with foreground segmented objects. The synthetic images can be created automatically with random positioning of the objects or, alternatively, the method can produce realistic images by keeping the realism in the scales and positions of the objects. Then, we employ Mask-RCNN deep learning model, to detect and segment classes of kitchen objects using images. In the experimental evaluation, we study both synthetic datasets, automatic or realistic, and we compare the results. We analyze the performance with the most widely used indexes and check that the realistic synthetic dataset, quickly created through our method, can provide competitive results and accurately classify the different objects

Advanced Speech Communication System for Deaf People

This paper describes the development of an Advanced Speech Communication System for Deaf People and its field evaluation in a real application domain: the renewal of Driver’s License. The system is composed of two modules. The first one is a Spanish into Spanish Sign Language (LSE: Lengua de Signos Española) translation module made up of a speech recognizer, a natural language translator (for converting a word sequence into a sequence of signs), and a 3D avatar animation module (for playing back the signs). The second module is a Spoken Spanish generator from sign writing composed of a visual interface (for specifying a sequence of signs), a language translator (for generating the sequence of words in Spanish), and finally, a text to speech converter. For language translation, the system integrates three technologies: an example based strategy, a rule based translation method and a statistical translator. This paper also includes a detailed description of the evaluation carried out in the Local Traffic Office in the city of Toledo (Spain) involving real government employees and deaf people. This evaluation includes objective measurements from the system and subjective information from questionnaire

High risk serotypes of the human papillomavirus (hpv) in patients With exofitic lesions in the oral cavity

Introduction: Oral squamous cell carcinoma has been associated with risk factors such as: tobacco consumption, alcohol and human papillomavirus, the authors determined the prevalence of high-risk serotypes of human papillomavirus infection in exofitic lesions of the oral cavity in a Cartagena hospital during the year 2014-2015. Material and Methods: an observational, descriptive, prospective and cross-sectional study was performed on 73 patients with verrucous lesions in the oral cavity, in which socio- demographic characteristics and the clinical and histopathological diagnosis were determined, and high-risk HPV was identified. The study complied with legal and ethical standards. The results were analyzed using descriptive statistics with the Stata v13.2 program. Results: The prevalence of HPV in the study population during the period 2014-2015 was 9.59% (n: 7). in none of the positive HPV cases in the histopathological study, any high-risk genotype was identified by the real-time multiplex PCR assay. HPV infection was more prevalent in patients in the third decade of life (29.5 years, DS ± 10.60), mean age was 62.8 years SD ± 17.74. The population came mainly from the rural area. The most common site was the labial mucosa. There was a relationship between smoking and the presence of HPV. Discussions: In the present study, no relationship of high risk HPV genotypes was found in the evaluated samples

Best available technologies for the heat and cooling market in the European Union

Every year, over 40% of the total energy consumed in Europe is used for the generation of heat for either domestic or industrial purposes whereas the cooling demand is growing exponentially. The importance of the heat and cooling sector is underlined in the EU energy policy initiatives. This emphasize the role of technologies based on renewable energy sources combined with high-efficiency energy technologies, to meet the heat and cooling demand in Europe more sustainably in the future. In this context, the JRC led study, which was undertaken with two partners , to identify the current best available technologies (BATs) which can contribute to improve the energy efficiency and reduce the CO2 emission in the heat and cooling market in the EU.JRC.F.6-Energy systems evaluatio

La conservación del patrimonio agroindustrial. Propuestas para la reutilización de los antiguos mataderos municipales y análisis de costes

La creciente demanda de alimentos en las áreas urbanas, junto con los avances en los transportes y la aparición de nuevas fuentes de energía propiciaron a finales del siglo XIX la construcción de diversas industrias agroalimentarias en el medio rural español. Un ejemplo de este patrimonio agroindustrial son los antiguos mataderos municipales, edificados en un gran número de localidades de la geografía española con el objetivo de evitar sacrificios clandestinos de ganado y de mejorar las condiciones higiénicas de la carne. Las cada vez mayores exigencias técnicas y sanitarias para este tipo de construcciones a partir de la década de los 70 y la progresiva sustitución de las instalaciones municipales por mataderos privados más modernos y de mayor capacidad provocaron el cierre y posterior abandono de muchos de estos edificios en las décadas siguientes. En el presen te trabajo se muestran cuatro propuestas concretas para la reutilización de este tipo de construcciones. A partir de la información recopilada de varios proyectos fin de carrera desarrollados por alumnos de la Escuela Técnica Superior de Ingenieros Agrónom os de Madrid, se describen las actuaciones y trabajos de rehabilitación necesarios en cada caso y se ofrece un estudio comparativo de costes entre proyectos de reutilización y obra nuev